I’ve had some trials and tribulations with HR on Reta.
My biggest concern was my max HR during intense exercise. It was registering almost 220 on my farming Fenix. I never felt my HR acting k like that. I got a chest strap and this concocted has abated, I am back exactly where I should be, 188.
After 5 months, my RHR is drifting slowly back down. I had been 48-53 ish, but it went up to 65-68. Now on steady 4mg for about 3 months, my RHR down at 62 and I expect it to drop below 60 over time.