How soon did you start feeling effects after first dose?

I considered reta, but I read that it could increase heart rate, which freaked me out a little.

On the positive side, higher heart rate can partly be from lower blood pressure. LDL may be better with reta than tirz. Also:

I switched from tirzepatide to Reta and until I moved up to 7 mgs had no appetite control. I added cagril and I can tell you it’s powerful I had to make myself eat. Also my bio markers also improved, normal bp, cholesterol numbers improved also recently has an echocardiogram done because I had a heart attack about 5 years ago. It showed a major improvement in left ventricular refraction the ability to pump blood. It has gone from 39 percent 2 years ago to 61 percent 3 weeks ago. That is in the normal range of a healthy heart. My cardiologist was amazed at the improvement and noted it in the report. He said it likely will be used to treat heart failure. Anyway that’s my experience and I’ve lost 96lbs in about 10 months.

There is also using tirz for ghetto reta (stacking with survo or maz) or stacking tirz with reta. For stacking though, cagri is a cleaner option. In any case, I will always be a tirz fan and still have more hoarded than reta.
 
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I considered reta, but I read that it could increase heart rate, which freaked me out a little. What made you want to make the switch from tirz to reta in the first place?
The added fat burning effect. But honestly it’s been eh. Working about the same as Tirz for me with a little extra heartburn. My resting HR went up about 10 beats a minute. From 70-80. My workout rate didn’t change. I max out at 160 and haven’t ever gone higher so Reta hasn’t affected that.
 
Odd one for me. I went to lunch ~1 hour after my first pin and got a meal I usually get. Got about half way through and had pretty bad onset nausea to the point where I couldn’t even fathom taking another spoon. Interestingly, I haven’t had that sort of sensation again even though my overall appetite is less, and I actually went back and had that meal a few weeks later with no major issues.

Was either first time exposure, or that I somehow injected straight into a subcut capillary or incredible placebo effect but spooked my initially.
 
Been on tirz for 6 months now. it's going to sound crazy, but day 2 is when I first noticed I had 0 interest in eating snacks, & really didn't want to have dinner either. Almost 6 months later, for me, I can barely eat. I definitely get protein & nutrient shakes in, & have very small meals from time to time. I'm trying to be better with it.
 

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