I think I might be dumb….

[Longstory]

Hi!

I’m so sorry, I just have one question that I need an answer to. I’ve read loads but I don’t seem to be able to find an answer that I understand. Here goes…

So my rats dosage of tirz is 15mg weekly.
You can buy tirz in 15mg vials. If I fill it up with 3ml bac water then the rat would use the full vial once per week.

I get that you could buy tirz 30mg and use half the dose.

If you bought 120mg tirz you would use 1/4 weekly out of the vial and the vial would last 4 weeks.

However, when reconstituted- does the vial last more than 4 weeks in the fridge?

Also I’ve seen some buy 300mg tirz and I’m wondering how you can draw a small enough dose out of the vial to administer if you can only add 3ml of bac water to a vial?

Obviously, buying in larger quantities is the most economical option. But I’m trying to figure out how you dose that small for something like tirz 300mg.

I’m sorry if I’m being stupid. I’ve tried some dosage calculators and don’t seem to understand them.

Can you put more than 3ml bac in a vial? Is that the answer? Or are the larger mg vials larger in actual size to accommodate more water?

I haven’t even got to bitcoin yet. Are there any vendors that accept different methods of payment? I’ve seen PayPal mentioned but when I look on vendors posts the say bitcoin only.

Thank you everyone for all the information so far, I think if I get my head around this question then I will be ok. 😊

 

[lessthanhalf]

I would suggest double checking your maths, for these medications or any medication it is pretty important to get it right.
"If you bought 120mg tirz you would use 1/4 weekly out of the vial and the vial would last 4 weeks."
This would be a dose of 30mg, which probably won't kill you but could give you a very unpleasant week or so with nausea and vomiting, with a not tiny risk of needing to be hospitalised for dehydration if the vomiting would not stop quickly, the half life of a week is a definite problem if you go too high in dosage too quickly or make a mistake. This is actually a real problem with grey peptides, poison call centers have had a lot of calls about dosing errors for glp medications, with the expensive brand name pens it is harder but not impossible to get it really wrong, but when you are mixing it up yourself, then getting it wrong by a factor of 2 or 10 is very easy. Thankfully they are safer than something like morphine where a 2 or 10 x dose error might actually kill you outright.
There are some online tools with peptide dosage/reconstitution calculators, that I do not have direct links for but would be easy to find with google, and would be a very good idea to double check and make sure you are not making dosing errors, especially if you are fairly new to this.
To answer your question the general advice is to use a vial in 30 days, but I personally would not be concerned using a 120 mg vial of tiz at 15mg/week for 8 weeks if it was kept refrigerated, you would lose a tiny amount to peptide degradation , and if you were careful with sterile technique and used bac water , risks of bacterial or fungal growth in 8 weeks in the fridge would be pretty low. Often the cost per mg is fairly similar for 60mg and 120mg vials in which case you might as well get the 60mg one and use it for 4 weeks.

 

[MsGizmo]

Use a peptide calculator. This is the one I use .. ---> Click here <---
Example
Input dose (15mg) lets say the amount in the vial is (60mg vial) Mixed with (2ml) of BAC and then it tells you to load 4 syringes with 50 units each or if you use a pen its 50 clicks.

 

[Longstory]

I would suggest double checking your maths, for these medications or any medication it is pretty important to get it right.
"If you bought 120mg tirz you would use 1/4 weekly out of the vial and the vial would last 4 weeks."
This would be a dose of 30mg, which probably won't kill you but could give you a very unpleasant week or so with nausea and vomiting, with a not tiny risk of needing to be hospitalised for dehydration if the vomiting would not stop quickly, the half life of a week is a definite problem if you go too high in dosage too quickly or make a mistake. This is actually a real problem with grey peptides, poison call centers have had a lot of calls about dosing errors for glp medications, with the expensive brand name pens it is harder but not impossible to get it really wrong, but when you are mixing it up yourself, then getting it wrong by a factor of 2 or 10 is very easy. Thankfully they are safer than something like morphine where a 2 or 10 x dose error might actually kill you outright.
There are some online tools with peptide dosage/reconstitution calculators, that I do not have direct links for but would be easy to find with google, and would be a very good idea to double check and make sure you are not making dosing errors, especially if you are fairly new to this.
To answer your question the general advice is to use a vial in 30 days, but I personally would not be concerned using a 120 mg vial of tiz at 15mg/week for 8 weeks if it was kept refrigerated, you would lose a tiny amount to peptide degradation , and if you were careful with sterile technique and used bac water , risks of bacterial or fungal growth in 8 weeks in the fridge would be pretty low. Often the cost per mg is fairly similar for 60mg and 120mg vials in which case you might as well get the 60mg one and use it for 4 weeks.

Thank you for this.
Sorry I meant a 60mg would last 4 weeks..
I had just got out of bed !

If the cost per mg is similar then yes I suppose it would make sense to get the 60mg depending on other costs like postage.

So are the people who are buying 300mg keeping the vials in the fridge for a longer period? As you said I think I might worry about contamination and degradation at that point.

So I think I’ll go with 60 or 120 to be on the safe side.

Thank you for your help.

Next stop supplies!

 

[Longstory]

Use a peptide calculator. This is the one I use .. ---> Click here <---
Example
Input dose (15mg) lets say the amount in the vial is (60mg vial) Mixed with (2ml) of BAC and then it tells you to load 4 syringes with 50 units each or if you use a pen its 50 clicks.

Thank you, I’ll take a look at that. 🙂

 

[cldfront]

Firsties - People who are buying 300mg Tirz are buying what is called a "kit", which is ten vials of 30mg each.

Second - If you are going to reconstitute a 15mg vial, I would only use 1ml BAC water because who wants to inject 3ml at once? That's a lot.

 

[Longstory]

Firsties - People who are buying 300mg Tirz are buying what is called a "kit", which is ten vials of 30mg each.

Second - If you are going to reconstitute a 15mg vial, I would only use 1ml BAC water because who wants to inject 3ml at once? That's a lot.

Ah! Ok!

Thank you so much for your help 😉

 

[chmuse]

Something I haven't seen mentioned-

If you do a 15mg vial, don't recon with 3ml. That's a huge amount of liquid for one dose- unless you're using a gigantic syringe you'll probably be doing 3-6 shots for one dose.

Name brand doses are .5 ml each regardless of mg.

 

[indolent]

1. At 15 mg per week, you'd want to buy a kit of 60mg (or more!) vials. Vendors will list 60mg for $x, but it's really a total of 600mg for that single price when you buy a kit.
2. You need to understand lab testing (and group testing) because (among other reasons) the contents are sometimes overfilled by up to 30%. You'd adjust at reconstitution.
3. The official recommendation is 4 weeks max refrigerated after reconstitution. Many here are comfortable with up to 12 weeks refrigerated for tirzepatide (assuming vigilant alcohol-swabbing). Prominent compounding pharmacies (this is a USA thing) send out a three-month supply of basically the same reconstituted vials, with instructions to keep them refrigerated.
4. Don't use a peptides calculator. Use a reverse peptides calculator. Stop the insanity!
5. Opinions differ, but I'd aim for 10-40 unit shots and let that guide your recon calculation. Less is more; your body has its own water to slowly dilute what you pin subcutaneously.
6. Walk away from the mindset that you're dividing a vial into x doses; run away from the mindset that you're adding a nice round number of mL of bac. Embrace a nice round number of units for injection, that being a numbered point on your syringes.
7. My current routine is to reconstitute the whole kit at once, then freeze all [big pharma advises not to freeze because of the mechanisms in their autoinjectors], keeping active-use vial in fridge (or even freezer, with quick thaw before each dosing). Then freezing the leftover bac for future use. Your comfort level might vary, and a downside to this is if you get into more elaborate protocols in the future (e.g. a smaller dose, but every 5 days) so carefully label or otherwise keep track of details like actual mg and bac volume in the vials.

 

[fatty33]

Firsties - People who are buying 300mg Tirz are buying what is called a "kit", which is ten vials of 30mg each.

Second - If you are going to reconstitute a 15mg vial, I would only use 1ml BAC water because who wants to inject 3ml at once? That's a lot.

How do you know how much bac water to use per vial?

 

[Mr. Blonde]

You can technically use as much or little bac per vial as you choose. Think basing it off how much you want to inject. Reconstitute with 1ml or 3ml (just examples) and one is a lot less liquid your blasting into your body.

Google peptide calculator. You can play around with dosages. It allows you to input mg of peptides, ml of bac water, and shows how much you would be injecting based on #s input.

 

[indolent]

How do you know how much bac water to use per vial?

Use the reverse calculator in my signature, shooting for a number of units per dose that corresponds with a marked number on your syringe between 10 and 30, such that anticipated increases in your dosage in mg will also fall on a marked number. The amount of bac water you add will probably not be a nice round number, but each time you draw a dose it'll be easier.

 

[cldfront]

How do you know how much bac water to use per vial?

It depends. Two schools of thought to consider:
1. Less BAC means less to inject, and less is more.
2. More BAC means less room for error, and more is more.
Choose your own adventure.
Or post your current dose amount and mg per vial of your meds and someone here will give you tips. We're (mostly) friendly. 🙂

 

[fatty33]

It depends. Two schools of thought to consider:
1. Less BAC means less to inject, and less is more.
2. More BAC means less room for error, and more is more.
Choose your own adventure.
Or post your current dose amount and mg per vial of your meds and someone here will give you tips. We're (mostly) friendly. 🙂

I have been looking at a lot of sites to try and figure out how it's done. I'm SLOWLY figuring it out but I am afraid to do it wrong. I don't want to be sick for a week. :/

I have used the dosage calculators but they confuse me. Maybe it's because I don't have a syringe to compare it to. I may have some syringes at work I can bring home to look at for reference.

Thank you for responding!!

 

[indolent]

I have been looking at a lot of sites to try and figure out how it's done. I'm SLOWLY figuring it out but I am afraid to do it wrong. I don't want to be sick for a week. :/

I have used the dosage calculators but they confuse me. Maybe it's because I don't have a syringe to compare it to. I may have some syringes at work I can bring home to look at for reference.

Thank you for responding!!

Use the reverse calculator instead. Insulin syringes basically come in 1.0 mL (100 units), 0.5 mL (50 units), and 0.3 mL (30 units) ... you can find photos online with a simple search. Pay attention to 1 unit vs 2 unit increments for the tick marks.

 

[lillypriceincrese]

Given that a Vial can be over filled, is it best do half or quarter what is stated to test it is not dangerously over filled. I know for example 10 mg feels like so if I did half even quarter and it felt Normal and no adverse effects,a week later do what should be 10mg .Of course the vial could be underfilled too .However that is not dangerous, just bad luck .

 

[MsGizmo]

Firsties - People who are buying 300mg Tirz are buying what is called a "kit", which is ten vials of 30mg each.

Second - If you are going to reconstitute a 15mg vial, I would only use 1ml BAC water because who wants to inject 3ml at once? That's a lot.

I think a person buying 15mg vials would be taking a lower dose. I personally wouldn't even buy vials smaller than a month supply each. If I was taking 10mg of Tirz per week for example .. the smallest I would buy are the 40mg vials.

 

[peptideusername]

Given that a Vial can be over filled, is it best do half or quarter what is stated to test it is not dangerously over filled. I know for example 10 mg feels like so if I did half even quarter and it felt Normal and no adverse effects,a week later do what should be 10mg .Of course the vial could be underfilled too .However that is not dangerous, just bad luck .

I'm sorry, what?
This guessing game can be avoided by having your peptides tested!

 

[cheaperseeker]

Keep in mind that many peptide calculators will have you enter the dose you want to take in MICROgrams (mcg), not milligrams (mg). 1 mg = 1000 mcg, so for a 15 mg dose you would enter 15000 mcg.

 

[chmuse]

Given that a Vial can be over filled, is it best do half or quarter what is stated to test it is not dangerously over filled. I know for example 10 mg feels like so if I did half even quarter and it felt Normal and no adverse effects,a week later do what should be 10mg .Of course the vial could be underfilled too .However that is not dangerous, just bad luck .

Please don't do this. It's not uncommon to be sent the wrong pep.

 

[Laxfinity]

Given that a Vial can be over filled, is it best do half or quarter what is stated to test it is not dangerously over filled. I know for example 10 mg feels like so if I did half even quarter and it felt Normal and no adverse effects,a week later do what should be 10mg .Of course the vial could be underfilled too .However that is not dangerous, just bad luck .

This is playing with fire and you can get very sick. Only buy tested vials and reconstitute to the amount on the COA.

 

[Garbo]

I'm sorry, what?
This guessing game can be avoided by having your peptides tested!

Do you ever get the sinking feeling you're fighting a losing battle ...

 

[MsGizmo]

Keep in mind that many peptide calculators will have you enter the dose you want to take in MICROgrams (mcg), not milligrams (mg). 1 mg = 1000 mcg, so for a 15 mg dose you would enter 15000 mcg.

So don't choose one of those.

 

[Carsten]

I would suggest thinking about this a different way. Less about how much of a bottle to take and more of a MG per ML dilution. Ultimately no matter what MG vial you buy, you are diluting the peptide with BAC water. The dilution is what matters.

So for example if you had a 30mg vial, you could dilute in 1ML (100 Units or 1 CC) and then your dose would be 50 Units ( .5 ML or .5 CC).

However the standard way most people would dilute a 30mg would be to use 3ML ( 300 Units or 3CC) so that the dilution is 10mg per 1ML. This makes the dosing easy because each 10 Units is 1mg. This of course would make your dosing difficult because you are on 15mg which at this dilution would be 150 units. Which is more than a standard insulin syringe can hold.

The only factor here that matters is MG per ML dilution. You can create any MG per ML dilution you wish,.

 

[lillypriceincrese]

This is playing with fire and you can get very sick. Only buy tested vials and reconstitute to the amount on the COA.

But how do I know ,just cause one viak is tested the other 9 will be the same weight. Surely it is better to take a smaller amount to test or am I missing something here .

 

[lillypriceincrese]

I would suggest thinking about this a different way. Less about how much of a bottle to take and more of a MG per ML dilution. Ultimately no matter what MG vial you buy, you are diluting the peptide with BAC water. The dilution is what matters.

So for example if you had a 30mg vial, you could dilute in 1ML (100 Units or 1 CC) and then your dose would be 50 Units ( .5 ML or .5 CC).

However the standard way most people would dilute a 30mg would be to use 3ML ( 300 Units or 3CC) so that the dilution is 10mg per 1ML. This makes the dosing easy because each 10 Units is 1mg. This of course would make your dosing difficult because you are on 15mg which at this dilution would be 150 units. Which is more than a standard insulin syringe can hold.

The only factor here that matters is MG per ML dilution. You can create any MG per ML dilution you wish,.

I kind of understand how to do the math based on what it says on the vial ,but say my 30mg vial was over or underfilled .Testing only counts for the one vial tested. I am just trying make sure I don't take too much .I can work out the calculations based on the vial but we have no way of telling if the vial is true weight or am I missing something .

 

[Carsten]

I kind of understand how to do the math based on what it says on the vial ,but say my 30mg vial was over or underfilled .Testing only counts for the one vial tested. I am just trying make sure I don't take too much .I can work out the calculations based on the vial but we have no way of telling if the vial is true weight or am I missing something .

So in this case there is no way to know exactly if the vial is over or under filled. Even batch testing from the same batch doesnt account for if a particular vial is over or under filled. Even if the powder contains the correct amount of active product, you can't be sure that each vial gets exactly the same weight worth of product. But order with a supply who has a good reputation and this should be less of an issue. Ultimately though we are all taking a small risk of if the vial is correctly filled. Sometimes it's an entirely different peptide, when the lab mixes things up.

Rare, but it happens.

 

[MsGizmo]

I kind of understand how to do the math based on what it says on the vial ,but say my 30mg vial was over or underfilled .Testing only counts for the one vial tested. I am just trying make sure I don't take too much .I can work out the calculations based on the vial but we have no way of telling if the vial is true weight or am I missing something .

Exactly. ALL of us are taking a risk just by injecting ourselves with something .. even if you get your GLP-1 from a pharmacy. Then there are the compounded versions. Then the grey market. Do we rely on the tests provided by the vender? Do we test as a group? Do we pay for our own tests. And yes .. even if we do our own tests the other 9 vials are going to be slightly different.

My personal risk level is buying from a well established vender and trusting their tests. I base my dosage on the mg listed in those tests. Sure, I am probably taking a tiny bit more or a tiny bit less. But its not enough to do anything to me.

For example .. lets say you have a goal of 15mg of tirz a week and you buy vials that are labeled as 60mg. So that vial is 4 doses. But .. let's say that vial is actually overfilled and is really 70mg. Each dose you take is really going to be 17.5mg. How much of a difference is an extra 2.5mg going to make assuming that your body was already used to getting 15mg?

 

[Carsten]

Exactly. ALL of us are taking a risk just by injecting ourselves with something .. even if you get your GLP-1 from a pharmacy. Then there are the compounded versions. Then the grey market. Do we rely on the tests provided by the vender? Do we test as a group? Do we pay for our own tests. And yes .. even if we do our own tests the other 9 vials are going to be slightly different.

My personal risk level is buying from a well established vender and trusting their tests. I base my dosage on the mg listed in those tests. Sure, I am probably taking a tiny bit more or a tiny bit less. But its not enough to do anything to me.

For example .. lets say you have a goal of 15mg of tirz a week and you buy vials that are labeled as 60mg. So that vial is 4 doses. But .. let's say that vial is actually overfilled and is really 70mg. Each dose you take is really going to be 17.5mg. How much of a difference is an extra 2.5mg going to make assuming that your body was already used to getting 15mg?

This is the same mindset I enter with. We are all taking some risk. Though, unless the vial is accidentally filled with insulin (Which would be completely insane mistake). Than its not going to kill you.

There is a chance you are 10% over or under dosed. I mean maybe even more than 10% if your supplier is exceedingly bad. The odds of getting the wrong dose? low to medium risk. The risk of immediate death upon injection? 0.0000000000000001%

 

[chmuse]

A t30 kit is like $100.
At 7.5mg that's about 9 months. 9 months of a 1200/month med for $100 TOTAL.
Do the test. It's worth it. If you don't want to join the like 10 testing servers that exist now, you can arrange with other people in the vendors server, the vendor doesn't give a crap especially if you let them poach your results to prove they're good. Or just choose a domestic lab, just research which ones don't suck.

If you want to go all in without paying for testing, good for you, but OP is clearly new and we don't need to add another level of things that can go wrong!