Igf -1 level (score ) before and after

Probably a dumb question, but if GH is what we are trying to raise here, why don’t we check for that too?

I get that the Igf-1 test is indirectly checking how our bodies handle the increase in GH, but it seems odd to not check that too (though it does look like a kinda expensive test)
 
Probably a dumb question, but if GH is what we are trying to raise here, why don’t we check for that too?

I get that the Igf-1 test is indirectly checking how our bodies handle the increase in GH, but it seems odd to not check that too (though it does look like a kinda expensive test)
Because it’s fleeting. Natural GH is released in pulses lasting seconds. rHGH peaks after a few hours then declines. IGF-1 is fairly stable over the entire day, and used by endocrinologists as the primary biomarker to diagnose GH deficiency or excess, and to monitor effectiveness of treatment with rHGH.
 
Because it’s fleeting. Natural GH is released in pulses lasting seconds. rHGH peaks after a few hours then declines. IGF-1 is fairly stable over the entire day, and used by endocrinologists as the primary biomarker to diagnose GH deficiency or excess, and to monitor effectiveness of treatment with rHGH.
So, is there much of a reason to ever check GH directly outside of suspected direct pituitary malfunction?
 

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