I'm switching from tirz 10 mg to sema, need some help

[tknhm]

Hello, i'm switching from tirz to sema since it was too strong for me, i lost 10 kg in two months with exercise and diet (cool), but the vomit, pain and stinky breath was too much.
I bought sema 15 mg.
1. How long has anyone kept it in the fridge after reconstitution? I think 30 days (quite standard, it's safe) but tbh after doing the math i bought too much even so.
2. Has anyone noticed less effectivity? switching from tirz to sema and with time in the fridge
Thanks.

 

[bbrewer]

If you were at 10 mg if Triz after 2 months, no wonder you have problems. There is no benefit in dosing that high so fast. If you try that with sema your likey to have even more problems. Just back off to the recommended dosing schedule.

 

[fetefille]

Like the other person said, it reads like you went too far too fast. You probably don’t need to change to sema, just back waaaay down on the tirz. And let me second this, if you go that far that fast with sema it will be much worse.

What dosing schedule did you follow on tirz? If following the “official” one, by the end of 2 months, you’d only be ready to start 7.5mgs.

Everyone goes at their own pace, but if you’re having GI problems like that, you need to slow way down. There are some folks that never go above 2.5 or 5mgs of tirz and say they’ve continued to lose. Your body is talking to you, listen.

 

[brentm]

Like the other person said, it reads like you went too far too fast. You probably don’t need to change to sema, just back waaaay down on the tirz. And let me second this, if you go that far that fast with sema it will be much worse.

What dosing schedule did you follow on tirz? If following the “official” one, by the end of 2 months, you’d only be ready to start 7.5mgs.

Everyone goes at their own pace, but if you’re having GI problems like that, you need to slow way down. There are some folks that never go above 2.5 or 5mgs of tirz and say they’ve continued to lose. Your body is talking to you, listen.

Great advice here...

Sema seems to be much more likely to cause you issues than Tirz will. If you decide to stick it out with Sema... absolutely follow the official titration schedule. Semaglutide is strong enough that you really need to build up to levels that others (like myself) can tolerate with little sides.