Injection Site Reactions Starting after 3 months

[CreepyZebra]

I've been running the following since March 18th and have never had a site reaction other than to the GHKcu. Now, 3 months later, I get ISR even with Reta. The reaction is an itchy welt similar to that of GHKcu but the Reta ISR occurs about 48hrs after pinning. I do not pin Reta and GHKCU in the same place as one another, and I rotate injections spots. I've tried reconstituting new vials of each, new BAC water, taking an antihistamine, and took a full week of all peps while I traveled. Has anyone had a similar experience?

Reta: split dose since 3/18 - Pinned in belly
NAD+: 3x a week since since 3/31
GHKcu: daily pinned in upper glute/love handles since 4/20

 

[UghItsStupidNIHateIT]

I've been running the following since March 18th and have never had a site reaction other than to the GHKcu. Now, 3 months later, I get ISR even with Reta. The reaction is an itchy welt similar to that of GHKcu but the Reta ISR occurs about 48hrs after pinning. I do not pin Reta and GHKCU in the same place as one another, and I rotate injections spots. I've tried reconstituting new vials of each, new BAC water, taking an antihistamine, and took a full week of all peps while I traveled. Has anyone had a similar experience?

Reta: split dose since 3/18 - Pinned in belly
NAD+: 3x a week since since 3/31
GHKcu: daily pinned in upper glute/love handles since 4/20

Are you wiping the tops with alcohol and yourself with alcohol prior to injecting? And do you filter?

 

[CreepyZebra]

Are you wiping the tops with alcohol and yourself with alcohol prior to injecting? And do you filter?

I do filter and wipe all the things before and after with fresh wipes. It's so bizarre.

 

[medavaca]

Try pinning with just your BAC water as a test.

 

[lessthanhalf]

I think the above comment is worth a try, but what you are describing are localised allergic injection site reactions, and are far more likely to be due to the peptides. Starting a while later is normal, your immune system has to get exposed to it to develop an allergy and it can take days to years. In the studies injection site reactions to GLP's are around 5% or so, and are mostly harmless but irritating. So long as there is no evidence of a systemic reaction, then it is just a question of putting up with it or changing to a different glp. There do seem to be some people who get reactions more than others as you are describing it from multiple peptides, there was one person on this forum who got them from sema , tirz and reta, and had done the bac water only test to confirm it. Sometimes injecting a bit deeper into the subcutaneous fat can reduce the reactions as there are lots of immune cells in the skin and less in the fat. One good thing is that although antibodies to GLP drugs are very common , they rarely effect the drug so are not neutralising, this is not the case with most other biological therapies.