Intermittent Fasting on glp

[casprow]

When you stop eating insulin drops, when insulin drops your body switches from sugar burning to fat burning.

So does that mean fasting everyday for like 4+ hours gives better results at burning fat ? Or is it just calorie game at the end of the day

And adding Retatrutide to it should boost the effects as well if I’m not mistaken

 

[Skidude]

I remember reading about fasting benefits as well as many controversial issues ; including as it relates to efficacy for men vs women.

I personally chose to use it as a tool to reach my goals and did 16/8 throughout my weight loss journey. My main motivation was the removal of visceral fat as I had the iconic old man pot belly shape..
Everything I read supporting it said 12 hours was a good starting point 12/12 and real benefits increased after that.
I did combine that with calorie reduction and minimum movement goals. (10k steps)

There are a few subreddits that can be read and lots of info online.
The online results might provide a more balanced view of pros and cons.
I did not have diabetes or pre-diabetes so that was not a concern.

 

[Good-Heart6425]

When you stop eating insulin drops, when insulin drops your body switches from sugar burning to fat burning.

So does that mean fasting everyday for like 4+ hours gives better results at burning fat ? Or is it just calorie game at the end of the day

And adding Retatrutide to it should boost the effects as well if I’m not mistaken

I’ve been intermittently fasting for >10 years to control reflux . I endorse its benefits wholeheartedly . The main drawback is that I cannot eat supper with friends, so socializing is limited.

 

[sheilarae74]

I have done OMAD quite a few days since I started reta back in January but I never saw any extra weight loss from it.

 

[Smiter]

Fasting is excellent if you can make it work. But weight loss will only depend on calorie deficit. Though the effects of fasting might make weight loss easier.

 

[FartfulCodger]

I find that OMAD comes naturally to me on Tirzepatide, at least while there's still enough concentration in my blood. I use split-dosing to keep that concentration more consistent. I know I haven't been getting enough protein, but I really wanted to focus on losing weight. Once I reach goal weight, my plan is to still eat light during the day, focusing on protein and nutrition in general.

 

[ColdSmoke]

Fasting is excellent if you can make it work. But weight loss will only depend on calorie deficit. Though the effects of fasting might make weight loss easier.

Of ffs. How many doctors have proven this to be untrue? 1,000? I can’t believe folks are still pitching the CICO nonsense.

 

[Smiter]

Of ffs. How many doctors have proven this to be untrue? 1,000? I can’t believe folks are still pitching the CICO nonsense.

paraphrasing another member here, Thermodynamics remain undefeated.

 

[ColdSmoke]

Folks on GLP-1s have mis regulated hormone/metabolism/etc… While you’re correct that you likely won’t lose weight without a calorie deficit, it’s certainly is not as simple as that.

The risk with running IF on GLP-1s is not getting your protein requirements in your small eating window. You’ll have to eat bigger meals to get you macros. This is a problem with you’re not hungry and have a sensitive stomach. Plus, the main purpose of IF is to drop glucose so you burn fat. GLP-1s do that on their own. So, I’m not seeing much benefit. I just listened to podcast about this. I’ll track it down.

 

[ScienceHippo]

I've been intermittent fasting on tirz most days, but no on purpose. I eat breakfast, I eat lunch, and then I'm not usually hungry in the evening. So I don't eat.

 

[ColdSmoke]

See attached from Apple Podcasts.

 

[Estarossa19]

Folks on GLP-1s have mis regulated hormone/metabolism/etc… While you’re correct that you likely won’t lose weight without a calorie deficit, it’s certainly is not as simple as that.

The risk with running IF on GLP-1s is not getting your protein requirements in your small eating window. You’ll have to eat bigger meals to get you macros. This is a problem with you’re not hungry and have a sensitive stomach. Plus, the main purpose of IF is to drop glucose so you burn fat. GLP-1s do that on their own. So, I’m not seeing much benefit. I just listened to podcast about this. I’ll track it down.

I'm on GLP's because I eat too much. GLP's have helped me eat less. Meaning less calories consumed = weight loss?

🤔

 

[Smiter]

The risk with running IF on GLP-1s is not getting your protein requirements in your small eating window.

I completely agree. Fasting while successfully losing weight on GL-1s is next to impossible, especially for long fasting windows.

Plus, the main purpose of IF is to drop glucose so you burn fat

Huh? I never thought of it like that. IF might drop insulin secretion but I always thought that the associated autophagy was the main goal of IF.

 

[ColdSmoke]

I’ve always thought of it as fat burning once blood sugar is gone and insulin is no longer running amuck. Autophagy doesn’t kick in until like 20-24 hours, maybe longer.

 

[ultima thule]

I'm on IF for nearly 3 years now, and when started Reta it's much more easy to do. Eat 2 meals per day. First one around noon, and second around 7pm. Once a week I do 24h fasting. It's Monday, cuz my busiest day in a week and don't do workouts then. The only downside now, when on Reta is providing sufficient amount of protein in 2 meals only. But whey protein powder is very handy to sort that issue. Anyway, I get used to that eating style. Just do the exceptions while on Holiday or some events like Xmas...then all hell breaks loose 😁

 

[Lear00]

Different perspective to those mentioned here already, I personally think IF could be quite dangerous whilst on these medications, especially if you do not currently have any degree of insulin insensitivity.

My baseline BGLs are around 6-8 mmol/L, and on Reta 4mg I’ve dropping to <3.5mmol quite consistently when I haven’t had anything to eat over 6+ hours.

Have a read about my experience here

Post in thread 'Blood sugar drop on Reta?'
https://glp1forum.com/threads/blood-sugar-drop-on-reta.10750/post-168250

 

[yrrdead]

I pretty much did this for my entire weight loss on Reta. Last calories before 0000. Then nothing until about 1500 when I get up (work nights). Most days were protein shake > small meal > small meal > protein shake in my 8-9 hour "feed" window.

I don't know that it had any effect. I didn't really notice anything positive or negative.

 

[onwuz1234]

Fasting is excellent if you can make it work. But weight loss will only depend on calorie deficit. Though the effects of fasting might make weight loss easier.

doesn’t fasting result in calorie deficit?

 

[Smiter]

doesn’t fasting result in calorie deficit?

not by itself...If folks overeat during their eating window...they would be in excess

 

[lessthanhalf]

I think there is some evidence of health benefits from intermittent fasting , it does reduce metabolic derangements, ( insulin resistance, liver fat etc ) but in the context of a low calorie diet on GLP's, I doubt it really changes the amount or rate of weight loss, assuming the number of total calories is the same.
CICO is absolutely true, so long as you are actually accurately measuring intake and output, thermodynamics is a bitch and cannot be gotten around. But in the real world no one ever measures intake accurately , calorie estimates are notoriously bad, and output is almost impossible to measure, except by back calculating energy consumption based on weight loss and 7700kcal/kg of fat lost.
CICO often seems wrong as a simplistic use of it does not take into account the huge amount of individual variation in energy expenditure, and usually fails to adequately account for drops in energy expenditure with weight loss, especially metabolic adaptation to chronic low calorie input. And the standard age / weight / calories used per day are just not really accurate enough to be that much use. I personally experienced energy expenditure drop 50% over 10 months of weight loss from 145kg to 75 kg, 50% is more than the standard formulas would suggest. And was the difference between losing 6kg per month and 0 kg per month on the same calorie input.

 

[Sloth1]

See attached from Apple Podcasts.

Thanks for this one, was just looking for something to listed to and this fits perfectly.

 

[Skidude]

The thing I find so interesting in this hobby is how much people are different, whether it be their reactions to the peptides, symptoms, goals, or their methods for reaching them.

Personally I kept a food journal to manage macros and monitor progress.

Although my methods may not work for all, it is hard to argue the benefits I have had.

in my first 31 weeks I averaged 9.5k steps a day, +/- 100 grams protein, +/- 1200 calories
I drank only water and black coffee in the morning with a calorie window between noon and 8pm.
This, combined with supplements and glp1s, allowed me to go from +/- 40" waist to 30-32"
I went from obese (226lb) to normal (163lb).

So does CICO, IF, GLP1s work? one or all did for me- I have maintained for 1 year now and am working on composition through increased calorie and protein, combined with some resistance.
YMMV

Here is a sample week from Sep 2024:

 

[kobeanbry24]

I started IF (like sikdude, water and coffee in am till I got hungry ) about 3 years ago to get my blood sugar levels down because I was prediabetic, which based on my labs has worked. Now that I've started reta, I think I'll go back to checking my blood sugar periodically.