Jeep Reta

I'm interested in testing. Started 1 month ago at 0.5mg. 6ft 290lbs male. Had no appmall. For 2 days. Next week did 1mg. Then 2 and last week 3mg. Felt no appetite suppression so far. Scale hasn't moved down but I feel like my body comp has been changing a bit (I workout 4-5 days a week). Should I jump to 6mg this week?
 
Tator said:
I'm interested in testing. Started 1 month ago at 0.5mg. 6ft 290lbs male. Had no appmall. For 2 days. Next week did 1mg. Then 2 and last week 3mg. Felt no appetite suppression so far. Scale hasn't moved down but I feel like my body comp has been changing a bit (I workout 4-5 days a week). Should I jump to 6mg this week?
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If I'm reading this right, you've only been on reta for 3-4 weeks with no consistent dose? No, you shouldn't jump to 6mg. Reta has a half life of six days, you need to build up to effective blood levels over time.

If you need appetite supression, try 2mg twice a week. Twice weekly dosage is effective for me. Be aware that this dose might make you sick since you haven't titrated up or followed any logic in your dosing at all.

For reference, I started at 0.5mg... I pinned that four times in a week to maintain appetite suppression, which took me to the starting dose of 2mg a week, which I continued at by dosing 1mg every 3 or 4 days. Now as I go into week 5, I'm doubling that by dosing 2mg twice weekly.
 
Tator said:
I'm interested in testing. Started 1 month ago at 0.5mg. 6ft 290lbs male. Had no appmall. For 2 days. Next week did 1mg. Then 2 and last week 3mg. Felt no appetite suppression so far. Scale hasn't moved down but I feel like my body comp has been changing a bit (I workout 4-5 days a week). Should I jump to 6mg this week?
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After overshooting and going way too high, I restarted my Reta journey at 4mg, mainly to figure out how to manage my side effects. At that dose, I basically stayed the same weight. At 5mg, same.

At 6mg - for me - I have dropped weight very quickly. YMMV, obviously. I’m 5 4 and weigh(ed) 167 lbs when I went to 6mg. But my experience is consistent with what I’ve been hearing – that for many people 6 mg is when things start to happen. After that, I hear it’s either 8 or 9 mg. I have not looked at any of the titration studies that were conducted. I can only speak regarding this N of 1.
 
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Retazempic said:
After overshooting and going way too high, I restarted my Reta journey at 4mg, mainly to figure out how to manage my side effects. At that dose, I basically stayed the same weight. At 5mg, same.

At 6mg - for me - I have dropped weight very quickly. YMMV, obviously. I’m 5 4 and weigh(ed) 167 lbs when I went to 6mg. But my experience is consistent with what I’ve been hearing – that for many people 6 mg is when things start to happen. After that, I hear it’s either 8 or 9 mg. I have not looked at any of the titration studies that were conducted. I can only speak regarding this N of 1.
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Thats a pretty high dosage. Anything over 2mg for me and I get very cold plus my skin gets very sensitive.
 
maven8518 said:
Its wild. The more posts I read about people's doses and sides and losses. The less reta makes sense lol.
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I think a lot of people enjoy exaggerating and using extreme language when describing the effects of these drugs. Probe their claims a bit and more often than not you'll hear that "an absolutely horrendous anhedonia" was actually them scratching an itchy spot a couple times a day.
 
maven8518 said:
Its wild. The more posts I read about people's doses and sides and losses. The less reta makes sense lol.
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My side effects are some heartburn on pin days. I and my wife are both on 6mg. Not sure how much difference this has made, but we've stuck with Lilly's test schedule. Started 2mg for 4 weeks, then bumped up 2mg every 4 weeks. Everyone is different. YMMV
 
RetCurious said:
Y'all are filtering that Jeep reta, right?

JEEP Reta 30mg Batch number: JP20250821

Sterility: TAMC - FAIL, TYMV - FAIL
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So, the TAMC and TYMV means bacterial and fungus contamination?

Would filtering even remove this?

Newbie here. I know nothing, but am curious; How common and How dangerous?
 
This was from a local group test I was a part of. The buyer of the batch is eating it sadly. As far as filtering...filtering removes 99.9% supposedly. That's fine for double checking a batch that tested ok or under limits. That's not enough for me with something KNOWN to have crap in it. Of course everyone has their own comfort level.

Note that when filtering....the filters have a limit of the contaminant they can clean. Without knowing how much (janoshik doesn't say) contaminant there is, you can't know whether filtering would possibly mitigate it.
 
RetCurious said:
Y'all are filtering that Jeep reta, right?

JEEP Reta 30mg Batch number: JP20250821
Mass and Purity: 33.24mg 99.865%

Endotoxins: 1.294 EU/Vial

Sterility: TAMC - FAIL, TYMV - FAIL
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This is a punch to the gut for someone who's been waiting on a Jeep shipment for over 3 weeks. I don't think I'd be confident in taking something that failed sterility like this, even with filtering. Is it really too much to ask for some semblance of safety standards with this stuff?
 
kj4otu said:
This was from a local group test I was a part of. The buyer of the batch is eating it sadly. As far as filtering...filtering removes 99.9% supposedly. That's fine for double checking a batch that tested ok or under limits. That's not enough for me with something KNOWN to have crap in it. Of course everyone has their own comfort level.

Note that when filtering....the filters have a limit of the contaminant they can clean. Without knowing how much (janoshik doesn't say) contaminant there is, you can't know whether filtering would possibly mitigate it.
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…I have 2 kits of this in route ask we speak. Lesson learned. Can’t just go by the mass and purity test COAs..
 
RJ760 said:
This is a punch to the gut for someone who's been waiting on a Jeep shipment for over 3 weeks. I don't think I'd be confident in taking something that failed sterility like this, even with filtering. Is it really too much to ask for some semblance of safety standards with this stuff?
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I had been waiting for several weeks, also. Sorry this happened to you.
💰💰💰💰💰🚽
 
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RetCurious said:
Y'all are filtering that Jeep reta, right?

JEEP Reta 30mg Batch number: JP20250821
Mass and Purity: 33.24mg 99.865%

Endotoxins: 1.294 EU/Vial

Sterility: TAMC - FAIL, TYMV - FAIL
Click to expand...
Low endotoxins would suggest a low level of contamination would it not? I would think this would be good if filtered and used with BAC water. There hasn't been a lot of testing for this until recently, but my suspension is that these results would probably be fairly common in what we have been using. Am I wrong in any of that?
 
5byfive said:
Low endotoxins would suggest a low level of contamination would it not? I would think this would be good if filtered and used with BAC water. There hasn't been a lot of testing for this until recently, but my suspension is that these results would probably be fairly common in what we have been using. Am I wrong in any of that?
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I think some folks might be ok with the endos, but from what I’ve heard it’s the TAMC and TYVM fails (bacteria, and fungal) that draw the most concern.
Veterans, correct me if I am wrong.
 
JoonyO said:
If, for instance, I'm filtering a 30mg vial with 3ml of BAC I will first recon the vial with only 2 or 2.5 BAC then filter that and use the remaining 1 or .5 BAC water necessary to reach a total of 3ml to "flush" any remaining pep left, from filtering, in the filter into the vial..I hope. Or at least that's my "strategery".
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Mine too, usually into a cartridge, or split into two for klow80
 
I think the standard view tends to be assume nothing is steril and filter everything. If that's the view, then knowing something has failed shouldn't really matter. It hits different when you see it, but I feel like, if we are being consistsnt, it shouldn't matter. Endos look low to me. I don't think it would be as big a concern if Jeep hadn't failed endo spectacularly recently. Like I said, I think this is likely typical of what we have been using and we just haven't had the proof.
 
5byfive said:
I think the standard view tends to be assume nothing is steril and filter everything. If that's the view, then knowing something has failed shouldn't really matter. It hits different when you see it, but I feel like, if we are being consistsnt, it shouldn't matter. Endos look low to me. I don't think it would be as big a concern if Jeep hadn't failed endo spectacularly recently. Like I said, I think this is likely typical of what we have been using and we just haven't had the proof.
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Yeah I hear you and I appreciate you guys saying it straight.

If the baseline is “assume nothing is sterile and filter everything,” then technically this doesn’t change much… it just hits different when you actually see a fail instead of assuming it in the background.

Endos didn’t really jump out to me either. I think a lot of the reaction is just timing after that recent mess, Same data, different feeling.

From what I’m hearing it’s sounding like this probably is what we’ve been using all along… We just didn’t have the results before.
 
Danger1212 said:
So, the TAMC and TYMV means bacterial and fungus contamination?

Would filtering even remove this?

Newbie here. I know nothing, but am curious; How common and How dangerous?
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The fact it is no longer sterile would mean bateria microorganisms would grow and endotoxins would build up which could lead to you getting ill or even septic shock if the amount reached unsafe levels and no filtering will remove endotoxins that I'm aware of.
 
QueenMuntha said:
Interesting. Here is Jeep's test for that same batch number. https://verify.janoshik.com/tests/80925-R30_8YSG7F76GKG2
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Makes me wonder why they only published mass and purity.

5byfive said:
I think the standard view tends to be assume nothing is steril and filter everything. If that's the view, then knowing something has failed shouldn't really matter. It hits different when you see it, but I feel like, if we are being consistsnt, it shouldn't matter.
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It does matter, TAMC and TYVM fails indicate an unsanitary half assed finishing process.
High endos seem to typically be from bad raws bought on the cheap, this one is considered okay but questionable for pharma grade by US standards.
"Good enough" quality controls would get your product recalled and factory shut down in the US.
 
RetCurious said:
Use a good filter and Hospira Bac and you'll probably never know someone sneezed on the open vials. 😆
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sick jim carrey GIF
 
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