Maybe it's time to create a forum topic for elorantide

[keangkong]

@ZippityDooDah Maybe it's time to create a new category for eloralintide. It's an amylin-based weight loss drug.

Right now, most weight loss drugs are what are referred to as GLP-1 drugs, including drugs that only work on the GLP-1 system and drugs that also work on the glucagon and/or GIP systems.

Here is a study describing a 48 week phase two study on elorantide. It produced a 20% weight loss over the 48 weeks in those who took the maximum dose.

Billings, et al. (pre-publication, 2025). Eloralintide, a selective amylin receptor agonist for the treatment of obesity - a 48-week phase 2, multicentre, double-blind, randomised, placebo-controlled trial. Lancet, doi-10.1016/S0140-6736(25)02155-5, https://1drv.ms/b/c/d63cedb6db1eefc3/Efm5F9RRts5JnrKihcpJoN0B1BE1tSjoKK_VUYjg43vc4Q?e=potceA.

I look forward to seeing other options for people who can't tolerate GLP-1 drugs, those who receive little benefit from them, and those who will need to take additional medication to meet their health goals.

 

[keangkong]

See also Hsia, et al (poster presentation, Obesity Week 2025). Eloralintide Phase 2 Study in Adult Participants With Overweight or Obesity - Design and Study Population, https://assets.ctfassets.net/mpejy6...AYS_ELORALINTIDE_SYMPOSIUM_DV-033298_V3.2.pdf.

 

[ZippityDooDah]

I don't see why not, but give me a chance to read up on it and consider if it's time for a new section over the weekend.