My doctor changed my TRT to Reandron

Omxxl

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Hey all.


47-year-old male. On TRT since 2022 — started in the US on 200 mg cypionate weekly. After moving back to Spain, I was prescribed 125 mg enanthate weekly.


I've been on this protocol for 4 months. Bloodwork is dialed in and I've dropped from 26% to 14% body fat. For the last 3 weeks I've also been running HGH at 2 IU/day, and I'm really happy with the physical changes.


Today I had my follow-up with my endocrinologist on the Spanish public health system and I left pretty pissed off: he took me off weekly enanthate and switched me to Reandron (testosterone undecanoate) 1000 mg every 3 months.


What's your take? Is it worth accepting the Reandron switch, or better to source enanthate/cypionate on my own and stick with what was working?
 
Hey all.


47-year-old male. On TRT since 2022 — started in the US on 200 mg cypionate weekly. After moving back to Spain, I was prescribed 125 mg enanthate weekly.


I've been on this protocol for 4 months. Bloodwork is dialed in and I've dropped from 26% to 14% body fat. For the last 3 weeks I've also been running HGH at 2 IU/day, and I'm really happy with the physical changes.


Today I had my follow-up with my endocrinologist on the Spanish public health system and I left pretty pissed off: he took me off weekly enanthate and switched me to Reandron (testosterone undecanoate) 1000 mg every 3 months.


What's your take? Is it worth accepting the Reandron switch, or better to source enanthate/cypionate on my own and stick with what was working?
I would switch to my own. I have a doctor prescribed vial so I can comfortably pack it on long trips (took a shot in hotel yesterday), but otherwise source it myself, because it is way cheaper that way. I personally wouldn’t want a such a long acting shot. I don’t think the 3 months schedule is even right either. I thought you have to take more frequent injections at first. And then you don’t know how fast your body will basically metabolize it, so the 3 months would even require dialing likely. I like to have much more control with bi-weekly shots. I don’t know any doctors in the USA that recommend that anymore either. I thought it was primarily just for convenience.
 
The previous dosage of 200mg weekly seems off...not the standard dosage for TRT.
Standard dosage is up to 125mg weekly. Anything more than that is for body building normally. The higher dosage will also cause higher estrogen levels, which in turn give you man-boobs.

As suggested, rather source your own test. It is more cost effective and you control the dosage.

Personally I like test cypionate.
 
On the positive side, a big advantage of test-u is (eventually) more stable test levels, with less stress on the cardiovascular system and less elevation of hematocrit.
 
On the positive side, a big advantage of test-u is (eventually) more stable test levels, with less stress on the cardiovascular system and less elevation of hematocrit.
Do you think that even if you were to compare to subq daily shots? They always say that about R but i think the problem is on the tail end and that is why people have to dial in whether it is every 10, 12, 14 weeks etc. I don’t have personal experience with R myself so don’t frankly know.
 
I would personally source my own. I don't know why your doctor would make such a drastic change. If it isn't broken, don't fix it. I didn't even know people still prescribed/used test-u.
 
The previous dosage of 200mg weekly seems off...not the standard dosage for TRT.
Standard dosage is up to 125mg weekly. Anything more than that is for body building normally. The higher dosage will also cause higher estrogen levels, which in turn give you man-boobs.

As suggested, rather source your own test. It is more cost effective and you control the dosage.

Personally I like test cypionate.
In the US, TRT dosages range from 70mg all the way up to 250mg a week. Everyone is different and requires different a dose. I take 150mg test-c and am at 1100 total test with an e2 of 50. My friend takes 250mg and sits around 850 total with 35 e2. There is no one size fits all protocol and forcing one is how we get problems like the OP is experiencing. His doctor has a protocol that he thinks is best and is prescribing it without tailoring it for his patient.
 
In the US, TRT dosages range from 70mg all the way up to 250mg a week. Everyone is different and requires different a dose. I take 150mg test-c and am at 1100 total test with an e2 of 50. My friend takes 250mg and sits around 850 total with 35 e2. There is no one size fits all protocol and forcing one is how we get problems like the OP is experiencing. His doctor has a protocol that he thinks is best and is prescribing it without tailoring it for his patient.
Wow, I took 250mg/week of testosterone cyp and my total t was 2028ng/dl but e2 was high at 118pg/ml
 
Wow, I took 250mg/week of testosterone cyp and my total t was 2028ng/dl but e2 was high at 118pg/ml
This makes the point how variable e2 it too. Just went back and looked at my e2 was still a bit under 50 when I was around 400mg. Even then, to me, a .125 Armidex on pins day was plenty. Yet some doctors now just prescribe AI as regular part of any 200mg trt. Curious what was your bfp when your e2 ran that high?
 
This makes the point how variable e2 it too. Just went back and looked at my e2 was still a bit under 50 when I was around 400mg. Even then, to me, a .125 Armidex on pins day was plenty. Yet some doctors now just prescribe AI as regular part of any 200mg trt. Curious what was your bfp when your e2 ran that high?
My bfp is high, 30.4% according to my "smart scale" but that's all I have to go off of. Currently only taking 100mg/week. Going to retest with my primary doc and go from there. The 250mg was self prescribed UGL. After seeing my e2 I realized I'm too fat for high dose at the moment. Will reasses after I lose more weight (Im down to 195lbs from 235 in January)
 
My bfp is high, 30.4% according to my "smart scale" but that's all I have to go off of. Currently only taking 100mg/week. Going to retest with my primary doc and go from there. The 250mg was self prescribed UGL. After seeing my e2 I realized I'm too fat for high dose at the moment. Will reasses after I lose more weight (Im down to 195lbs from 235 in January)
You read my mind. I was going to say too high of bfp though…. Yes, you should see wildly different e2 numbers after cutting down. Good luck!
 
You read my mind. I was going to say too high of bfp though…. Yes, you should see wildly different e2 numbers after cutting down. Good luck!
Yeah, I knew that but did anecdotally like the high total and free testosterone level. But gonna have to wait till I lose more fat
 
De vorige dosering van 200 mg per week lijkt niet te kloppen... dat is niet de standaarddosering voor TRT.
De standaarddosering is maximaal 125 mg per week. Alles daarboven wordt doorgaans gebruikt voor bodybuilding. Een hogere dosering leidt ook tot hogere oestrogeenwaarden, wat op zijn beurt kan leiden tot borstvorming bij mannen.

Zoals al gesuggereerd, is het beter om zelf een test aan te schaffen. Dat is kosteneffectiever en je hebt zelf de controle over de dosering.

Persoonlijk geef ik de voorkeur aan testosteroncypionaat.
Dikke onzin . Als je shbg waarde hoog is heb je meer testosteron nodig om goede waarde te krijgen. En als je op 200 mg last Krijgt van borst vorming ben je gewoon te dik. Op 15 a 16 procent vetpercentage heb je nergens last van . Erboven wel doordat vetcellen oestrogeen bezitten. En dit vrijkomt door de synergie met testosteron. Probeer bloed te prikken en ga rond 900 tot 1000 pmol/ l te gaan zitten. Dan heb je de testosteron spiegel te pakken net als toen je 21 jaar oud was. 125 mg testosteron kan voor iemand wel voldoende zijn maar het is zeker geen one size fits all oplossing.
 
On the positive side, a big advantage of test-u is (eventually) more stable test levels, with less stress on the cardiovascular system and less elevation of hematocrit.
I am struggling with higher hematocrit at any dose and am curious if you have any first hand knowledge or experiences to share concerning "less elevation of hematocrit"? Thank you.
 
I am struggling with higher hematocrit at any dose and am curious if you have any first hand knowledge or experiences to share concerning "less elevation of hematocrit"? Thank you.
My 2 personal experiences - blood donation once every 3 months and making sure you don’t run b12 too high.
 
My 2 personal experiences - blood donation once every 3 months and making sure you don’t run b12 too high.
Let me add, most people don’t believe excessive b12 raises hemocrit, but you asked for personal experience. But trt doctors do teach the blood donation one.
 
Might be better to source your own. That way you can control your levels better and avoid huge dips and spikes.
 
Hey all.


47-year-old male. On TRT since 2022 — started in the US on 200 mg cypionate weekly. After moving back to Spain, I was prescribed 125 mg enanthate weekly.


I've been on this protocol for 4 months. Bloodwork is dialed in and I've dropped from 26% to 14% body fat. For the last 3 weeks I've also been running HGH at 2 IU/day, and I'm really happy with the physical changes.


Today I had my follow-up with my endocrinologist on the Spanish public health system and I left pretty pissed off: he took me off weekly enanthate and switched me to Reandron (testosterone undecanoate) 1000 mg every 3 months.


What's your take? Is it worth accepting the Reandron switch, or better to source enanthate/cypionate on my own and stick with what was working?

Honest opinion. if you are going to be on long term TRT and not interested in cycling and want medical replacement, Reandron is a great choice for anyone who wants to avoid being pinned frequently.

Heres where your doctor is making a poor decision. Check out the blood concentration levels of Reandron, a drug with a 53 day half life, while adminstering 1000mg every 90 days.

The swings and valleys are wild man, nothing wrong with Reandron but your doc needs to even out those hormonal swings, over the course of 1 year you swing from 1500s to 400-500

Screenshot 2026-04-30 at 2.49.35 PM.webp


Monthly injections of 333 looks much more sensible
Screenshot 2026-04-30 at 2.55.20 PM.webp
 
Last edited:
Let me add, most people don’t believe excessive b12 raises hemocrit, but you asked for personal experience. But trt doctors do teach the blood donation one.
I have my primary doctor overseeing my TRT but I have a hematologist for phlebotomies when necessary. Big problem is it crashes my iron/ferritin and causes a plethora of negative symptoms. I have also read high b12 helps formulate more red blood cells causing hematocrit to rise. Thx for reminder!
 

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