My doctor just told me to stack Tirz and Sema

[Vacation4us]

Just saw my endocrinologist yesterday. I am currently on Zepbound 15 mg ( actually taking amopure T60 while I stockpile). BMI is 25 and he wants me under. Since switching from Wegovy to Zepbound it’s slow going. So he offered me a sample pen of Oz to add .25 mg and titrate up as needed to achieve some more weight loss.

I'm told him I had leftover 2.4 mg Wegovy pens and we discussed me cracking open those pens and using them.

Just thought those stacking or thinking of stacking might be interested.

 

[flannel]

Considering that sema has such a higher affinity for GLP-1, it's not crazy, but it's also not a great first suggestion on his behalf. Metformin increases intrinsic GLP-1 activity while lowering your sugar/insulin and appetite... Bupropion would increase your metabolism and decrease your appetite while increasing energy levels. There's a ton of augmentation you can do before going off the reservation.