Sounds like you might be someone who like myself generally tolerates substances in large amounts. I feel ya. The strategy I’ve landed on is cycling from one to the next to the next—high-dose sema to tirz to reta and back to sema again—so there is always somewhere else to go. If you keep just piling more on top, eventually you’re just going to have a massive tolerance to everything, nothing will work anymore, and then what do you do?
Slow down, it’s a marathon not a sprint. Switch to reta for a while, be prepared for some weight gain while it gets spun up, and stick with it for a few months. Eventually, if you plateau, instead of adding a bunch of crap just switch to sema.