Nexaph T30 Failed Sterility (T30 pre sale Christmas batch)

[Grogu]

mind sharing your thoughts? I'm interested.

My thoughts are mostly surrounding the weak links in a lot of the things we do involving grey. We really don't know a lot about most things. We don't know who or how these peptides are manufactured, how vendors manage their inventory systems, or how lab professionals are trained or how they operate. When we participate in groups, we don't know if the individuals running them are related to vendors or have other motivations. And all of this is conducted under a veil of anonymity with disposable accounts and mostly untraceable exchange of funds.

So, the conflicting results actually raise more questions than answers.

• Can we trust either lab's results?
• Can we trust the manufacturing process?
• Can we trust the independence of testing groups?
• Can we trust that the anonymity protecting participants isn't equally protecting bad actors?

So, as distrubing as this may sound, it might actually have been better for Jano's second set of tests to confirm the original results and those of TrustPointe. I'm not sure what people are supposed to think with this second round of testing. In my mind, a sense of relief shouldn't be it.

 

[Turbo-Farmer]

A failed sterility test could have been what is called a "false positive" and may have been due to laboratory error. This is often due to the skill/ experience of the tech performing the test. This can also be due to a variance in the testing supplies or environmental conditions. I'm not sure of the iso certification status or GLPs in place at any of the laboratories in discussion. There's too many variables in play to compare one lab to another.

 

[tncc_rn]

No sure if anyone has been following, but back in January an independent test group tested a Nexaph batch of T30 (2TZ3012242025-20) and received a failed sterility TYMC (Yeast/Mold) result from Jano. This was for the Christmas 12/23 Tirz 30mg Pre-Order. The cap/crimp colors are red/green. There are a bunch of different red colors caps.

A group over on TG collected another 40 vials (I think) for additional sterility testing and sent some to TrustPointe and some to Jano. The results from TrustPointe recently came back and 3 out of 4 batches failed sterility. I think everyone was hoping that the failed sterility result on the one vial from the independent group was a one-off (perhaps a failed seal or lack of vacuum on a specific vial), but the issue appears more widespread.

I personally didn't buy this batch, but have other Nexaph products. So, I contributed to the additional testing costs, but the group is open to everyone over on TG if anyone has this batch.

Why is anyone surprised. A large chunk of that batch T30/60 from MIXX was bought by a reseller right around the time Nexaph ran out of the same. Then the sterility issues came out about MIXXs T30/60. Figure Kane bought what he could from whom he could to keep his customers happy. This is probably T from the MIXX batch. Even ABC had sterility failures with their T30/60 a few months ago. If one company fails, chances are they all will since almost all of these peptides are sources from the same manufacturers.

 

[staffn1]

Are there any reports of infections from injecting grey peptides that could be caused by sterility fails?

 

[Turbo-Farmer]

Biologix® 13mm Sterile PES Syringe Filter, 0.22µm, 100/pk

High-throughput Biologix® sterile PES syringe filters. Ideal for biological fluid filtration. >98.5% protein recovery. Multiple diameters. Shop now!

biologixusa.com

Wish they sold 4mm filters. But they don't. (That said, if you're filtering 3ml vials, as I expect most of us are, The 13mm is the correct size filter. 4mm for up to 1ml, 13mm for 1 to 5ml)

Sterile, price point one of the best I could find ($.51/ea), free shipping, and 5 days from order to on the doorstep.

Not a dirtball shape-shifting sleazy Amazon seller who may or may not be selling counterfeit product.

Gotta admit, I'm kinda fed up with Amazon lately.

Biomed Solution Sterile Syringe Filter, PES/Nylon/PTFE Membrane 0.22/0.45um Pore Size, 4mm Membrane Diameter,Individually Packaged (PES 0.22um, 100pcs): Amazon.com: Industrial & Scientific

Biomed Solution Sterile Syringe Filter, PES/Nylon/PTFE Membrane 0.22/0.45um Pore Size, 4mm Membrane Diameter,Individually Packaged (PES 0.22um, 100pcs): Amazon.com: Industrial & Scientific

a.co

4mm 0.22 u syringe filters on the zon. They are more pricey, but the individual blister packaging is nice

 

[tncc_rn]

Seriously? You have the presumption of quality when buying medical grade product to inject. When the facts change, I change my mind. That's why.


Well said.

Keep in mind, all these peptides sold by ALL these distributors are sold " FOR RESEARCH PURPOSES ONLY. NOT TO BE USED FOR HUMAN OR ANIMAL CONSUMPTION." The idea that they would be worried about supplying contaminated peptides to the market is laughable. The ONLY time these drug dealers care is if their actions significantly cut into their sales and profits. The only time.

 

[YoYoFat]

failed sterility TYMC (Yeast/Mold) result from Jano.

The organism ID is: Staphylococcus pasteuri

Who identified the organism ID? Because that’s bacteria, not yeast/mold. Bacteria isn’t found via TYMC testing. TAMC is.

That said, staphylococcus pasteuri is not typically dangerous. It’s found on almost all of our skin, and can be transferred to a vial simply by handling it. That is to say, this could be from those who sent in the vial, from Jano, who knows.

 

[YoYoFat]

Nexaph is the vendor. I believe that Nexaph claims to manufacturer themselves in the US, but I’m not so sure about that.

Manufacturing is a multi step process.

They import the raws from China, they don’t make the raws themselves. Then they lyophilize and finish in the U.S.

 

[CNCCurrency]

Biomed Solution Sterile Syringe Filter, PES/Nylon/PTFE Membrane 0.22/0.45um Pore Size, 4mm Membrane Diameter,Individually Packaged (PES 0.22um, 100pcs): Amazon.com: Industrial & Scientific

Biomed Solution Sterile Syringe Filter, PES/Nylon/PTFE Membrane 0.22/0.45um Pore Size, 4mm Membrane Diameter,Individually Packaged (PES 0.22um, 100pcs): Amazon.com: Industrial & Scientific

a.co

4mm 0.22 u syringe filters on the zon. They are more pricey, but the individual blister packaging is nice

The biologix ones are individually sealed also

 

[Turbo-Farmer]

Who identified the organism ID? Because that’s bacteria, not yeast/mold. Bacteria isn’t found via TYMC testing. TAMC is.

That said, staphylococcus pasteuri is not typically dangerous. It’s found on almost all of our skin, and can be transferred to a vial simply by handling it. That is to say, this could be from those who sent in the vial, from Jano, who knows.

My guess is defective stoppers, so many variables. I have see this one on a lio run at a fill finish facility. I'm basing this on my own experience and meantion of failed sterility from another supplier

 

[deluge]

The idea that they would be worried about supplying contaminated peptides to the market is laughable.

One word for you: "Staphylococcus_pasteuri".

[maybe 2 words. Or 2 with a hyphen?].

Either way, you first.

Here's a fun read:

Staphylococcus pasteuri infective endocarditis: A case report - PMC

Staphylococcus pasteuri is a coagulase negative bacterium which although formally described in 1993, has only recently become possible to reliably speciate in diagnostic microbiology laboratories. S. pasteuri remains an extremely infrequent cause of ...

pmc.ncbi.nlm.nih.gov

Staphylococcus Pasteuri Infective Endocarditis
TLDR; It's rare. He didn't die. Aortic valve replacement. 3 year prognosis "retains pre- morbid function". Laughable?

​

 

[Grogu]

Who identified the organism ID? Because that’s bacteria, not yeast/mold. Bacteria isn’t found via TYMC testing. TAMC is.

That said, staphylococcus pasteuri is not typically dangerous. It’s found on almost all of our skin, and can be transferred to a vial simply by handling it. That is to say, this could be from those who sent in the vial, from Jano, who knows.

I should have be clearer.

TrustPointe identified the organism.


The original fail from Jano was on TYMC


The original fail resulted in the collection of multiple vials for further sterility testing. I'm not a lab technician, but I would think that there should be some type of protocol so that bacteria on the outside of vials doesn't end up in the testing medium. But this could have something to do with it. I'm not sure that the individual vials sent to the labs were from the same collector.

 

[Grogu]

On a somewhat related note, I just read on TG that recent batches of T40 and T60 from Alice failed sterility testing and in response the group buy organiz3r offered refunds to her customers. She is also selling the failed T40 kits at a discounted price of $85, with full disclosure of the sterility failure. Thank you, but no thank you, but there will probably be some takers.

 

[peppystrings80]

His business model was to build a reputation with pre-sale testing, low-ish prices, and quality guarantees, and then getting away with raising prices while reducing quality and service because of the inertia of said reputation. I’ll admit, my expectations of the guy are extremely low but not replacing a batch that fails sterility surprises even me.

Anyway, the higher price point you’re paying is pure manipulation, he offers exactly nothing exceptional. This was foreseeable from the very beginning of his little endeavor.

I agree with you 💯

 

[Turbo-Farmer]

One word for you: "Staphylococcus_pasteuri".

[maybe 2 words. Or 2 with a hyphen?].

Either way, you first.

Here's a fun read:

Staphylococcus pasteuri infective endocarditis: A case report - PMC

Staphylococcus pasteuri is a coagulase negative bacterium which although formally described in 1993, has only recently become possible to reliably speciate in diagnostic microbiology laboratories. S. pasteuri remains an extremely infrequent cause of ...

pmc.ncbi.nlm.nih.gov

Staphylococcus Pasteuri Infective Endocarditis
TLDR; It's rare. He didn't die. Aortic valve replacement. 3 year prognosis "retains pre- morbid function". Laughable?

​

Definitely immune compromised,

 

[cldfront]

The mods on Nexa TG have multiple times cited that all products are "lyophilized in a Level 5 ISO clean room" which is part of the reason why I've always been willing to pay more for Nexa product and never filter (even though I own filters) and have recommended them to people who are not smart enough to learn the details of making sure their meds are legit. I thought they were idiot-proof and sent them idiots. Now I feel like the idiot... one of my friends purchased for the first time in late November and now has an itchy/inflamed site reaction on the third and four vial. Rawr.

 

[CNCCurrency]

The mods on Nexa TG have multiple times cited that all products are "lyophilized in a Level 5 ISO clean room" which is part of the reason why I've always been willing to pay more for Nexa product and never filter (even though I own filters) and have recommended them to people who are not smart enough to learn the details of making sure their meds are legit. I thought they were idiot-proof and sent them idiots. Now I feel like the idiot... one of my friends purchased for the first time in late November and now has an itchy/inflamed site reaction on the third and four vial. Rawr.

I doubt the red itchy is from the batch, just a histamine reaction which usually goes away eventually from what I have seen.

 

[fatty33]

Who identified the organism ID? Because that’s bacteria, not yeast/mold. Bacteria isn’t found via TYMC testing. TAMC is.

That said, staphylococcus pasteuri is not typically dangerous. It’s found on almost all of our skin, and can be transferred to a vial simply by handling it. That is to say, this could be from those who sent in the vial, from Jano, who knows.

interesting

 

[Habibibi]

I should have be clearer.

TrustPointe identified the organism.
View attachment 18028

The original fail from Jano was on TYMC
View attachment 18029

The original fail resulted in the collection of multiple vials for further sterility testing. I'm not a lab technician, but I would think that there should be some type of protocol so that bacteria on the outside of vials doesn't end up in the testing medium. But this could have something to do with it. I'm not sure that the individual vials sent to the labs were from the same collector.

Is that from the same vial?

 

[yrrdead]

Biologix® 13mm Sterile PES Syringe Filter, 0.22µm, 100/pk

High-throughput Biologix® sterile PES syringe filters. Ideal for biological fluid filtration. >98.5% protein recovery. Multiple diameters. Shop now!

biologixusa.com

Wish they sold 4mm filters. But they don't. (That said, if you're filtering 3ml vials, as I expect most of us are, The 13mm is the correct size filter. 4mm for up to 1ml, 13mm for 1 to 5ml)

Sterile, price point one of the best I could find ($.51/ea), free shipping, and 5 days from order to on the doorstep.

Not a dirtball shape-shifting sleazy Amazon seller who may or may not be selling counterfeit product.

Gotta admit, I'm kinda fed up with Amazon lately.

I hear you on amazon but with this specific product I ordered on amazon but got it direct from biologixusa. Which I thought was strange but I'll take it.

 

[Grogu]

Is that from the same vial?

Different vials, but reportedly same batch.

 

[Habibibi]

Different vials, but reportedly same batch.

Ah OK, I'm not sure what conclusions can be drawn here since sterility varies from vial to vial, and can fail in multiple ways .

 

[conzopiriani]

Can we not say PGB anymore?? Am I about to find another Easter egg??

 

[chmuse]

I agree with you 💯

I learned a while ago that bee is almost always right

 

[deluge]

Manufacturing is a multi step process.

They import the raws from China, they don’t make the raws themselves. Then they lyophilize and finish in the U.S.

I don't doubt that they import from Chyna, and don't make the raw products.

That said, give me any proof whatsoever that they do the lyophilizing/finishing in the US. I'd love it if they did. But I doubt it.

They are a simple reseller. Nothing more. (My opinion only. Prove me wrong).

 

[CNCCurrency]

I don't doubt that they import from Chyna, and don't make the raw products.

That said, give me any proof whatsoever that they do the lyophilizing/finishing in the US. I'd love it if they did. But I doubt it.

They are a simple reseller. Nothing more. (My opinion only. Prove me wrong).

 

[deluge]

I hear you on amazon but with this specific product I ordered on amazon but got it direct from biologixusa. Which I thought was strange but I'll take it.

Can you provide a link? I'd love to see a BiologixUSA product sold on Amazborg. Especially a 4mm PES filter.

 

[yrrdead]

Can you provide a link? I'd love to see a BiologixUSA product sold on Amazborg. Especially a 4mm PES filter.

This is what I bought ; https://www.amazon.com/dp/B0BCFRX3PN

Sold by biologixusa, came shipped in their box.

No luck on the 4mm though that I found, I got some off of undergroundsupply.

 

[Grogu]

There was a recent Alice TFC T40 batch that failed sterility and the group buy vendor offered refunds to buyers, but also put the ~70 vials she had up for sale for $85 and they sold out in a day. The vendor fully disclosed the test results, so there is a market for these despite the sterility testing.

 

[chewonmysac]

Just picked up two kits on the pre-sale. Might pick up 3 more. This batch will likely be the most tested batch in this company's history. They know they need to step their game back up. I am here for it. Sometimes the best time to fish is after the storm.