I have a question for you guys, I'm finding lots of information on what different peptides do and dosing information. But I'm not finding good information on shelf life and proper storage. I've asked Chat GPT (I know, not always reliable that's why I'm taking it with a grain of salt) about storage and shelf life for semax. Chat GPT says semax is only good for 24 - 48 hrs in the fridge. This can't be right. Shouldn't a whole vial last until it's gone? Is this even the right place to be asking this? Just trying to figure out exactly what to purchase and how much because I don't want my peps going bad and me flushing what little money I have down the toilet.
Peptide shelf life
- Thread starter eydiz
- Start date
zpped
Moderator
That chart is both extremely conservative (most peptides last WAY longer in each situation) and also not nuanced enough (i.e. HGH cannot be frozen once, tirz can)
There is no actual answer to your question because every batch can perform different, but the guidelines above are fine. But more importantly, the vendor will sell anything that someone will buy. That should answer this question.
Its only speaking of freezing lyopholized peptides. You shouldn’t be freezing anything that’s been reconstituted. You are 100% correct about HGH but I don’t think the OP is at that level yet.
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zpped
Moderator
You should read that chart again if that's what you think. The last row is frozen reconstituted
zpped
Moderator
You're the one posting a chart that recommends it...
It’s been corrected.
I saw this today and now I’m questioning a lot…
“What confuses people is they assume 0c (32f) is the freezing temp, and their freezer is well below that. So despite temp variation of a few degrees, there's no risk of freeze/thaw.
0c is the freezing temp of *pure* water. When there are solutes present, freezing temp is lower. Like salt on road ice.
Realistically that means a freezing temp range of -10c to -60c for almost all peptides.
So if your freezer is set to -20c, but swings between -17c and -22c, and your peptide residual moisture freezes at some temp within that range, like -18c, you're freezing and thawing it multiple times a day, for years.
Without knowing this ice transition temp, essentially impossible. refrigeration is safer as long as the time in storage is reasonably short like a year or so.”
“What confuses people is they assume 0c (32f) is the freezing temp, and their freezer is well below that. So despite temp variation of a few degrees, there's no risk of freeze/thaw.
0c is the freezing temp of *pure* water. When there are solutes present, freezing temp is lower. Like salt on road ice.
Realistically that means a freezing temp range of -10c to -60c for almost all peptides.
So if your freezer is set to -20c, but swings between -17c and -22c, and your peptide residual moisture freezes at some temp within that range, like -18c, you're freezing and thawing it multiple times a day, for years.
Without knowing this ice transition temp, essentially impossible. refrigeration is safer as long as the time in storage is reasonably short like a year or so.”
GLP1Pharmacist
Recently Joined
I have seen some post about not freezing NAD+, anyone have data to suggest refrigerator or freezer?
zpped
Moderator
That person is horribly confused about what they are talking about. Lyophilized peptides cannot be "frozen" or "thawed" because they have no water content. They are already a solid and would require EXTREME heat to transition to a liquid.
Unless they are talking about freezing reconstituted peptides?
nonyabizznez
GLP-1 Specialist
Had me up until "peptide residual moisture". Where are we seeing this exists in lyophilized GLPs? This would defy the definition of lyophilization.
(I had to narrow that down to GLPs because of recent NAD+ that looks more like what you'd find on the rim of a Margarita! 🤣)
(I had to narrow that down to GLPs because of recent NAD+ that looks more like what you'd find on the rim of a Margarita! 🤣)
Calm Logic
GLP-1 Specialist
For me, the problem with refrigeration (compared to freezing) for lyophilized is more potential for moisture from the fridge to get into the vial through any gaps in the vial. I assume no seal is perfect, given enough time anyway. But desiccants near the vial could help.
