Peptides for just Food Noise suppression?

[healthyanon]

I've just started tirz for a month and its working like crazy, started with the usual 2.5mg but I'm down to 1.25mg now at week 3 since I'm struggling to eat enough to have energy during the day.

I love the mental food noise suppression, its making me eat incredibly healthy and stops the impulsive binge eating but the delayed gastric emptying is causing my stomach to feel like its got knots in it for 2-3 days after injection even at the 1.25mg dose. I want to lose about 5kg more before maintaining but staying on tirz seems kind of overkill and not so desirable considering the side effects...

Are there any alternative peptides that just target food noise?

 

[MsGizmo]

The side effects fade after a bit. If its too much for you to take then lower your dose again. Try 1mg or even .75mg for couple of weeks. None of the peptides that reduce hunger are going to be side effect free.

 

[healthyanon]

The side effects fade after a bit. If its too much for you to take then lower your dose again. Try 1mg or even .75mg for couple of weeks. None of the peptides that reduce hunger are going to be side effect free.

Sure, I'll continue reducing the dose for now, was just wondering if there was any alternatives out of curiosity that have maybe less side effects by affecting less things within the body.

 

[Abrakebabra]

Cagrilintide is an option people sometimes turn to supress appetite - although that's not its sole purpose. Plenty of discussion about its use on these forums to have a look at.

 

[MsGizmo]

Sure, I'll continue reducing the dose for now, was just wondering if there was any alternatives out of curiosity that have maybe less side effects by affecting less things within the body.

As far as I know tirz has the least amount of side effects which is why I didn't try to suggest anything.

 

[Sid the SeaGull]

Cagrilintide is an option people sometimes turn to supress appetite - although that's not its sole purpose. Plenty of discussion about its use on these forums to have a look at.

I looked at this myself . I got a bit overwhelmed reading about reconstituting challenges with BAC and pH that's different. I ended up giving up and just sticking to Reta. Shame , I would have liked to try it

 

[Chili777]

I have some Cagri on order for when I go to maintenance mode. I hope it works out. I have Hospira, but it sounds like I'll need some AA also.

From https://pep-pedia.org/peptides/cagrilintide

Important: pH CRITICAL: Cagrilintide requires acidic pH (3.5-4.5) to prevent fibril formation. Standard BAC water (pH 5.5-6) is acceptable for short-term use (<30 days). For optimal long-term stability, acidify to pH ~4.0 with 0.6% acetic acid.

 

[CNCCurrency]

I have some Cagri on order for when I go to maintenance mode. I hope it works out. I have Hospira, but it sounds like I'll need some AA also.

From https://pep-pedia.org/peptides/cagrilintide

Important: pH CRITICAL: Cagrilintide requires acidic pH (3.5-4.5) to prevent fibril formation. Standard BAC water (pH 5.5-6) is acceptable for short-term use (<30 days). For optimal long-term stability, acidify to pH ~4.0 with 0.6% acetic acid.

debatable on ph in aftermarket versions.

 

[tubby]

Sure, I'll continue reducing the dose for now, was just wondering if there was any alternatives out of curiosity that have maybe less side effects by affecting less things within the body.

This is one of those "be careful what you wish for" situations. Just about anyone who has attempted a very-low calorie diet (independent of GLPs) will tell you that the symptoms that come along for the ride there (even setting hunger aside) aren't generally preferable to the common GLP symptoms.

Not to say you shouldn't try another approach like cagrilintide. In fact I kind of hope you do because I think solo-cagrilintide therapy would be interested to read about on here. Just that the grass over there may not be as green as what you're looking for.

 

[dirtyharry]

So Retarutide is the only GLP I have experiance with at the moment but I do plan on ordering some Tirzepitide to maybe stack the two.

On Retarutide I do still get hungry, but it isnt impulsive. As in, the hunger isnt some compelling force of nature that demands satiation like it did before. The only time I get REALLY hungry is after exerting myself either at the gym or when I go for a walk. Now, I can litteraly feel my body fueling up when I eat, and then using that fuel when I hit the gym.

With that said, the food noise supression isnt too overwelming so I definitely don't have trouble eating when I need to. For referance, I'm currently doing 3mg a week.

 

[healthyanon]

This is one of those "be careful what you wish for" situations. Just about anyone who has attempted a very-low calorie diet (independent of GLPs) will tell you that the symptoms that come along for the ride there (even setting hunger aside) aren't generally preferable to the common GLP symptoms.

Not to say you shouldn't try another approach like cagrilintide. In fact I kind of hope you do because I think solo-cagrilintide therapy would be interested to read about on here. Just that the grass over there may not be as green as what you're looking for.

Yeah thats my issue as well. I'm not significantly overweight (maybe 5kg), nor am I looking to diet down to crazy body fat percentages. I just want to suppress food noise so I'm not magically drawn to consuming trash food all the time. I just want less sugar/fat cravings.

So Retarutide is the only GLP I have experiance with at the moment but I do plan on ordering some Tirzepitide to maybe stack the two.

On Retarutide I do still get hungry, but it isnt impulsive. As in, the hunger isnt some compelling force of nature that demands satiation like it did before. The only time I get REALLY hungry is after exerting myself either at the gym or when I go for a walk. Now, I can litteraly feel my body fueling up when I eat, and then using that fuel when I hit the gym.

With that said, the food noise supression isnt too overwelming so I definitely don't have trouble eating when I need to. For referance, I'm currently doing 3mg a week.

Hmm yeah might be a thing to try though I'm not sure I want the heart rate increase that comes with it. I've dropped the tirz to 1.25mg now and the knot my stomach resolves the next day but its still a bit shitty because I usually sleep bad that night. Sadly the food noise suppression is also considerably weaker after 3 days. I still can't eat very much but the craving for sweet/intense stuff is definitely more present which is kind what I wanted to dodge... I thought about injecting twice a week but that still 2 nights of bad sleep a week.

 

[randompersonrandom]

Maybe consider Survo. I can't speak to what Survo is like without tirz, because I've never done it, but I stack it lightly against my Tirzepatide in part because the effect it has for me is that food is just not all that interesting. Tirz alone has that effect, but there was a big jump in that "meh" when I added Survo.

 

[lavender]

I have some Cagri on order for when I go to maintenance mode. I hope it works out. I have Hospira, but it sounds like I'll need some AA also.

From https://pep-pedia.org/peptides/cagrilintide

Important: pH CRITICAL: Cagrilintide requires acidic pH (3.5-4.5) to prevent fibril formation. Standard BAC water (pH 5.5-6) is acceptable for short-term use (<30 days). For optimal long-term stability, acidify to pH ~4.0 with 0.6% acetic acid.

Why switch to cagri for maintenance?

 

[Chili777]

Why switch to cagri for maintenance?

It's part of the calculation I'm doing in my head for when I reach goal weight. It's not so much a switch as it is an addition, as I titrate down on Reta. I'm one of the responders that gets almost complete appetite suppression from Reta and I want to maintain that. So as I titrate Reta downwards, I'll compensate by slowly adding Cagri, starting around 500 mcg, and adding another 500 mcg for each 2.5-3 mg of Reta I reduce.

I'm sure I'll have to make adjustments on the way, and I might be overthinking it, but I'm trying to create a transition so that I can keep my appetite in check as I've heard quite a few stories of that not happening. Eventually, I'd like to get to 1-2 mg of Reta per week and stay there for all the benefits I've received, over and above weightloss.

 

[HereKittyKitty]

Sure, I'll continue reducing the dose for now, was just wondering if there was any alternatives out of curiosity that have maybe less side effects by affecting less things within the body.

I didn't have much in the way of side effects on sema. Sema was great for my food noise. Had the testing results of higher doses of sema been released (or if I had been aware) I likely wouldn't have switched to Tz.

Food noise is real. And really disruptive.