Personal blog on Reta

[AngieHolmes]

Stats:

32M – 174 cm – 95 kg – BMI: 31

Bought two 5 mg vials from a Dutch website. I'm seriously overpaying, but at least I don't have to worry about customs seizing the package.

First dose: 0.5 mg of Retatrutide, injected on Sunday at 9 PM.

I went to bed about two hours later and didn't sleep at all that night. The next day, I skipped breakfast (which is normal for me). For lunch, I ordered something that I would normally finish in a couple of minutes, but I couldn't finish the entire plate. The same thing happened at dinner. My appetite was a little reduced.

The second night, I slept a little better, but still not as well as I should have.

However, by then my hunger had returned to normal. The cravings never really left.

Today, I slept better with some assistance, although I still could have used a few more hours of sleep. Hunger remains about the same, and the cravings are still haunting me.

I'm currently contemplating increasing the dose to 1 mg this coming Sunday.


*Translated and polished with AI 🙂

I'm doubtful you'll get better appetite suppression by increasing reta. Could you try adding some tirz instead?

 

[ZetsuM]

I'm doubtful you'll get better appetite suppression by increasing reta. Could you try adding some tirz instead?

I could, but tirz already has some of the components/mechanisms that reta has. How would it work better? Or am I misunderstanding something?

I've also been looking into Cagri for hunger suppression.

 

[AngieHolmes]

I could, but tirz already has some of the components/mechanisms that reta has. How would it work better? Or am I misunderstanding something?

I've also been looking into Cagri for hunger suppression.

From my mass intake of comments lol, my impression is tirz offers better appetite suppression compared to reta. That might especially be the case if you want to keep the reta at a relatively low dose. Doubling up on 2/3 receptors provides better appetite suppression, plus the glucagon benefits of reta. I guess I am biased towards tirz vs cagri as it seems less extreme in its effects, and has a greater research foundation. In fact, you might decide tirz gets you all of what you need. It's cheaper, too.

Since it sounds like this is your first GLP1, you may or not be someone who responds to low doses; that seems to be the luck of the draw. I wish you the best.

 

[ZetsuM]

From my mass intake of comments lol, my impression is tirz offers better appetite suppression compared to reta. That might especially be the case if you want to keep the reta at a relatively low dose. Doubling up on 2/3 receptors provides better appetite suppression, plus the glucagon benefits of reta. I guess I am biased towards tirz vs cagri as it seems less extreme in its effects, and has a greater research foundation. In fact, you might decide tirz gets you all of what you need. It's cheaper, too.

Since it sounds like this is your first GLP1, you may or not be someone who responds to low doses; that seems to be the luck of the draw. I wish you the best.

I've been reading multiple perspectives both on and off this forum. There's so much information out there that it's hard to know what's accurate and what's not.

I've never taken anything remotely comparable to peptides or weight-loss drugs before (I tried metformin, but it made me shit my brains out so i stopped after a few days).

So I wanted to be careful with dosing something that basically requires me to trust information from the internet. 🙂

 

[AngieHolmes]

I've been reading multiple perspectives both on and off this forum. There's so much information out there that it's hard to know what's accurate and what's not.

I've never taken anything remotely comparable to peptides or weight-loss drugs before (I tried metformin, but it made me shit my brains out so i stopped after a few days).

So I wanted to be careful with dosing something that basically requires me to trust information from the internet. 🙂

I get it. Given that, you might be better off with a substance that, if you get a pure supply, is well-researched and has a relatively low risk profile like tirz. The info behind it isn't "from the internet," it's from numerous well-done studies.

I'm not on commission for tirz, I swear! For some reason I want to steer you towards the least risky stuff. Going straight to reta . . . isn't that. And adding cagri especially isn't that.

Reta is the strongest GLP1 we have semi-easy access to, and something a lot of people reserve for when tirz stops working, not the first out of the gate solution. Body builders with lots of experience have good results, but it's probably not necessary for GLP1 virgins.

 

[ZetsuM]

I get it. Given that, you might be better off with a substance that, if you get a pure supply, is well-researched and has a relatively low risk profile like tirz. The info behind it isn't "from the internet," it's from numerous well-done studies.

I'm not on commission for tirz, I swear! For some reason I want to steer you towards the least risky stuff. Going straight to reta . . . isn't that. And adding cagri especially isn't that.

Reta is the strongest GLP1 we have semi-easy access to, and something a lot of people reserve for when tirz stops working, not the first out of the gate solution. Body builders with lots of experience have good results, but it's probably not necessary for GLP1 virgins.

I understand what you're saying.

I'll probably finish my current vials first (I paid a lot for them) and see where they get me.

I'll hold off on adding Cagri if the risks outweigh the benefits, and instead consider stacking tirz while keeping the reta dose low.

My girlfriend has taken Mounjaro, but she didn't experience huge effects either. The weight loss seemed to stall after the first week or so, which was probably mostly water weight anyway.

That's actually one of the reasons I decided to make the jump to reta. 🙂

 

[Crowreap]

I've been looking into cagri aswell but i don't want to overdo it. As soon as i finish my D.D.... I might order a few more peps i've been looking into.

Yeah, definitely do not want to overdo it because cagri is super strong with its main effects and side effects. But if you were to try out stacking reta and cagri, just know that you're gonna be full all day and bowel movements get slowed down like crazy which I guess is a good thing cause it keeps you satiated. And start small with cagri. I started with 266 micrograms and post-injection day, I get slightly fatigued. And I've injected it twice now. And the effects are still going very strong. I'm gonna have to monitor it for the next month or two. And most likely will not have to titrate up and will remain on this maintenance dose. But only time will tell.

 

[lessthanhalf]

I am just going to put this in to disagree with anyone recommending adding extra peptides to a super tiny dose of reta. Until you have been on the drug at least a few months and got the dose up to 4mg at least ( unless you respond well to low doses and do not need to increase that much ) , you are not going to have much of an idea of how well it will work for you in terms of controlling appetite and in terms of side effects. Everyone saying reta has less appetite suppression than tirz might be accurate, but the difference is actually small, the simple fact that reta causes more weight loss than tirz makes it basically impossible for it to cause less or at least much less appetite reduction, even accounting for the glucagon agonism pushing up energy expenditure 100-200 kcal/day at higher doses.

Reta is currently the most effective GLP there is for weight loss, so if you start it you should give it an adequate trial to see how well it works, and at current doses it should not be causing much appetite reduction, doses will need to go up. Adding in extra peptides at this stage is going to make it extremely hard to work out which peptide is having the effect you want or side effects making future dose decisions more difficult. And even if the risk is only a few percent , drug allergies are not that rare and doubling or tripling your risks for no real benefit is not a great idea.

I have no issues with using combinations for severe obesity when further weight loss is needed at maximum doses of one GLP, and sometimes it is useful if doses are limited by side effects, but hunger is still a problem, but this mainly applies to adding in low dose cagri as it is the only one working on different receptor systems. I think a lot of the people on middling doses of tirz plus reta would do just as well on a larger dose of one or the other.

What you want to achieve, reducing food noise and the compulsion to eat should be very achievable, not sure how overweight you are, but assuming side effects are tolerable gradual dose increases should get you there. If reta specific side effects are a major issue, due to sympathetic nervous system stimulation causing issues like insomnia, switching to tirz would be a better solution than adding it to reta. Not going to help much if the side effects are more general GLP ones like GI side effects.