Personal blog to record my Sema + Reta journey

TinyPCOSgirl

GLP-1 Apprentice
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Mar 28, 2026
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Hello,

I will use this thread as a personal blog to record my sema+reta journey.

I am stacking with 2.4mg of wegovy (semaglutide) and 0.5mg retatrutide.

I JUST administered my shot with Reta 20 minutes ago.

I am stacking sema and reta because I don’t want my prescription to go to waste. I am using sema on Monday nights and Reta on Thursday nights.

My starting point is 104.8 lbs (I am 4ft 9in tall.) My goal is to be around 94-96 lbs in four weeks, since I have an event to attend.
 

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Progress looks great!

0.5mg reta is a great stacking dose, but if you ever transition to reta completely you should probably increase your dose sharply if you want to maintain the appetite suppression and avoid bouncing back.

I'm a fella, and this is anecdotal, but I find that myo and d-chiro inositol in the morning seems to aid in reducing my appetite as well – and I understand it's often suggested for PCOS. (Don't buy ovasitol it's overpriced!)

Good luck hitting your goal and feeling skinny at the function! I've been counting calories and running a lot and I'm down about 12lbs in 3 weeks. This stuff is lovely.
 
Progress looks great!

0.5mg reta is a great stacking dose, but if you ever transition to reta completely you should probably increase your dose sharply if you want to maintain the appetite suppression and avoid bouncing back.

I'm a fella, and this is anecdotal, but I find that myo and d-chiro inositol in the morning seems to aid in reducing my appetite as well – and I understand it's often suggested for PCOS. (Don't buy ovasitol it's overpriced!)

Good luck hitting your goal and feeling skinny at the function! I've been counting calories and running a lot and I'm down about 12lbs in 3 weeks. This stuff is lovely.
Thank you!

Yes I’m on shitton of supplements for my PCOS. And yes, miyo d-chiro is one of the suppliments.

I feel pretty fine under 0.5mg of Reta.

I think I will up it next week to 1.0mg.
 
48hour update: I don’t feel any side effects except for tender abdominal muscles. It’s most tender in the pin spot. But it’s nothing unbearable or intolerable.
 
Hello,

I will use this thread as a personal blog to record my sema+reta journey.

I am stacking with 2.4mg of wegovy (semaglutide) and 0.5mg retatrutide.

I JUST administered my shot with Reta 20 minutes ago.

I am stacking sema and reta because I don’t want my prescription to go to waste. I am using sema on Monday nights and Reta on Thursday nights.

My starting point is 104.8 lbs (I am 4ft 9in tall.) My goal is to be around 94-96 lbs in four weeks, since I have an event to attend.


1 week update.

My weight is currently 102.8lbs. I lost 2 lbs since last Thursday!

I administered my Wegovy shot on Monday night and I am having gastro issues now. I'm going to the bathroom frequently and flushing a lot. But I welcome it since it's helping to reduce extra water weight.

Tomorrow, I administer by 2nd Reta shot. I will increase my dosage to 1.0mg.
 
That's a great combo should shred some serious weight on it. Are you doing any lifting?
 
That's a great combo should shred some serious weight on it. Are you doing any lifting?
Nope. No exercise or lifting. This is mostly sedentary. The only walking I do is less than 5k steps a day: a commute to-and-from work.

I’m mostly watching my diet.

I’m sticking to mostly one meal a day which consists of a protein source and a soup.
 
Update:

I just administered my 2nd dose of Reta 1.0mg dosage.

My weight right now is 103.6.lbs.

Hopefully I lose 3lbs by next Thursday 🙏
 
Nope. No exercise or lifting. This is mostly sedentary. The only walking I do is less than 5k steps a day: a commute to-and-from work.

I’m mostly watching my diet.

I’m sticking to mostly one meal a day which consists of a protein source and a soup.
Please standby. A mandatory, weekend-warrior gym bro will be assigned to you. Prepare now by drinking a gallon of milk twice a day. Resistance is futile.
 
Please standby. A mandatory, weekend-warrior gym bro will be assigned to you. Prepare now by drinking a gallon of milk twice a day. Resistance is futile.
I'd love that! I am thinking of hiring a calisthenics coach in the New York City area.
 
Update:

I just administered my 2nd dose of Reta 1.0mg dosage.

My weight right now is 103.6.lbs.

Hopefully I lose 3lbs by next Thursday 🙏
UPDATE:

Tomorrow is almost Tuesday and I did not lose te 3lbs. Its is partly my fault. I normally do One meal a day. And yesterday, I had two meals, wich has caused me to remain at 103.6lbs. Otherwise, I would have been 102.0 - 101.8 lbs today.

Since taking 1.0mg of Reta. I'm feeling the side effects now. I feel constipated; my body is finding difficulties to flush. I also have a slight bloated feeling from the constipation.

Due to late eating last night, I plan to complete a 36 hour fast, and only have green juice today to help with the bloat and constipation.

Tonight is my Wegovy dosage. Hopefully that will push things along.
 
FINAL UPDATE.

As of Friday May 14, 2006, I ended this Journey being 100.6 lbs.

I went from 104.8 lbs since April 16, 2026. to 100.6 lbs on May 14, 2026.

That's a total loss of 4.2lbs in 4 weeks.

Honestly, I think I would have gotten better results had I used Tirzepatide with Reta.

Now that I'm back from my vacation, I am now 107.0 lbs.

I have two more syringes of wegovy left under my insurance. I will definitely transition to Terzepatide in two weeks and start a new thread with my new journey of stacking Terz+Reta.
 
Actually, I lied.

I’m going to update this thread a few more times until my semaglutide completely runs out of prescription.

My current weight right now is 102.6lbs.

I think most of the weight from my vacation was just water weight. Hence why I was able to shed it so quickly.

I just need to lose two more pounds to reach my pre-vacation weight, 100.8lbs.
 

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