Killswitch97
GLP-1 Novice
🚫No Source Discussion🚫
Thoughts on filling my syringes of tesa and having them ready for the week? Anyone do this
Pre filling syringes?
- Thread starter Killswitch97
- Start date
GLP-1 Novice
BNLFL
GLP-1 Specialist
Why? Doesn't matter to me, just curious. How many times a week are you pinning?
This is a huge nope, for me. Syringes are not meant to hold things long term. If you choose to do this, it ups your chances of at the very least, ISRs and at the worst infections like cellulitis.
Killswitch97
GLP-1 Novice
🚫No Source Discussion🚫
Just to make night time routine a little faster. Wasn’t sure if the rubber would break down in the syringe. Figured it wouldn’t work was just curious
LabRatts
GLP-1 Enthusiast
What is the mechanism by which one sterile delivery method can become unsterile by “time”, CandyCap? Can you explain your “huge openness” to me like I’m 5?
Tesamorelin is a once daily injection, preferably at night. Off label, people often cycle 5 days on and 2 days off, mostly due to cost.
Killswitch97
GLP-1 Novice
🚫No Source Discussion🚫
Figured as much. Wasn’t sure if the syringe would break down and cause issues. Thanks for the input
LabRatts
GLP-1 Enthusiast
If you’re loading for a short duration I’ve seen zero evidence of that being a poor practice as of yet. If one can load a pen vial with similar rubber stoppers, etc then degradation of that is not any issue.
The notion that prefilled syringes may be dangerous might be shocking news to the likes of Eli Lilly and others who package some of their drugs in PRE-Filled syringes.… 😂🤣🫡
Just out of curiosity, what Eli Lilly product is supplied in a pre-filled insulin syringes? I’ve had Zepbound pens, and that’s definitely not a pre-filled insulin syringe and the delivery mechanism is totally different.
RubbaDubba1
GLP-1 Enthusiast
I've done 2-3 weeks worth of pre-filled syringes and haven't had a problem. I saw on here, someone mentioned to store the needle end upright. I keep them in a labeled Ziploc bag, upright in a coffee cup. I think they're a nurse and they did it themselves.
BNLFL
GLP-1 Specialist
I personally don't think it's a major deal to load the syringe at the pin time. OP, just curious, what's your weapon of choice for the injection?
LabRatts
GLP-1 Enthusiast
Rubber stoppers and plastics abound, what's the exact difference between the formulation of the 30 day use monthly pens from the big pharma folks versus the plastic in an insulin syringe, Grogu?
In the compound tirzepatide subreddit, there are tons of accounts of folks getting their medication supplied to them from their med-spa or doctor's office via insulin syringes. And all have survived, we think 😂. So, although something I personally wouldn't do, it's probably not gonna kill you.
Medivant, a 503b outsourcing facillity, actually has pre-filled syringes, but we're talking apples to oranges as their pre-filled syringes are pretty slick (glass).
MACKMATT HEALTHCARE
SEMAGLUTIDE & TIRZEPATIDE BEVACIZUMAB (AVASTIN®) ORTHOPEDIC DEVICES DERMAL FILLERS
mackmatt.com
bogardbilla
GLP-1 Apprentice
Pre-filling syringes is perfectly fine:
healthy.kaiserpermanente.org
www.healthcentral.com
myhealth.alberta.ca
Storing Insulin and Prefilling Syringes | Kaiser Permanente
Health Article description.
healthy.kaiserpermanente.org
Can You Prefill Insulin Syringes?
Learn if it’s safe to pre-fill insulin syringes, the risks involved, and best practices for storing insulin.
Storing Insulin and Prefilling Syringes
RubbaDubba1
GLP-1 Enthusiast
Even some peptide celebs, will do a couple weeks worth.In the compound tirzepatide subreddit, there are tons of accounts of folks getting their medication supplied to them from their med-spa or doctor's office via insulin syringes. And all have survived, we think 😂. So, although something I personally wouldn't do, it's probably not gonna kill you.
Medivant, a 503b outsourcing facillity, actually has pre-filled syringes, but we're talking apples to oranges as their pre-filled syringes are pretty slick (glass).
MACKMATT HEALTHCARE
SEMAGLUTIDE & TIRZEPATIDE BEVACIZUMAB (AVASTIN®) ORTHOPEDIC DEVICES DERMAL FILLERS
I have no horse in the race, but first, the mechanism that holds the medication, at least for a Zepbound pen, is a glass vial with a pretty substantial plunger. That's definitely different than a cheap .15cent insulin syringe. The syringe and needle is substantial. The green thing is the mechanism that pushes the plunger when the spring is activated. The syringe below is in a used state.
I've never had a multi-use pen, but I'd imagine we're talking about glass and different types of plastics than an insulin syringe, but what do I know, I'm not even from this planet 🤣
Yeah, I'm sure. I definitely don't think it will kill you. To me, it's not a big deal to draw and then inject, but I'm only doing two injections a week. If I was doing more, I'd definitely look into pens first, before prefilling syringes. That's just me. Everyone has different risk tolerances.
LabRatts
GLP-1 Enthusiast
Touche' on the planetary existence thing. Perhaps in a galaxy far far away the plastics are of a differing nature. FWIW, I've had re-usable pens that seemed more poorly made than some insulin one time use syringes... We're all never more than a lil rubber stopper away from a sheer calamity though, agreed? Hang in there, and thanks for the response-
AlexSilver
GLP-1 Enthusiast
Prefilling is a major hassle compared to pens. Pens make it easy and quick.
Another rabbit hole, but eventually will probably go down that hole.... I would like to do tesa at some point and think pens would be easier to deal with on daily basis.
jordekorn
GLP-1 Enthusiast
I pre fill for a couple days to a week, I’m not dead yet. I also fill and let it sit on the nightstand for a few hours so I can inject halfway through my sleep. (3 hours with no food basically, and during a sleep cycle- I like to eat before bed, because I get up at 3am for work and don’t eat breakfast.)
Before I joined here and started learning a lot more about peptides I prefilled my Sema into insulin syringes. I've got quite a few stored up from my compounded stash.
I've not seemed to have been harmed and the pep seems to still be working.
I would change to pre-filling fewer at a time and not 6 weeks worth.
I've not seemed to have been harmed and the pep seems to still be working.
I would change to pre-filling fewer at a time and not 6 weeks worth.
Rolltide61
GLP-1 Enthusiast
I don't think I'd prefill anything w/ GHK in it. I have this vision of the copper breaking down the rubber.
Raptorrunner
GLP-1 Apprentice
it takes under 30 seconds to wipe the stopper, uncap the syringe, draw the units and wipe the stopper again.
You can find an extra 30 seconds in your routine.
randompersonrandom
GLP-1 Specialist
I went down the rabbit hole, and I shouldn't have. I ultimately returned to the V1 pens that I started with, they work fine and I didn't really need to chase that 0.0001% easier unicorn I was after.
skeptick
GLP-1 Enthusiast
Mounjaro comes in pre-filled syringes, 4 to a package, used 1 per week, all dosage levels(2.5mg, 5mg. 7.5mg, 10mg, 12.5mg,15 mg), all use .5ml liquid. Easy to transfer all 4 prefilled syringes to a LurLoc syringe thence into a 3ml cartridge to use in a pen and can adjust/split dosages...
bogardbilla
GLP-1 Apprentice
Also, a reminder that our beloved Hospira BAC water sits in a plastic bottle with a rubber stopper, usually for much longer than 30 days.
woundcarping
GLP-1 Specialist
Comparing what comes from a regulated sterile production environment that’s supplied in sterile packaging to what we do with our alcohol wipes in our homes is laughable.
I don’t have a problem with water based solutions sitting against the plunger… not a fan of doing it with oil based.
Exposing the needle to atmosphere, drawing the solution, then storing it for a period of time before inserting it in the body is a contamination vector. So is the needle exposing the medication to atmosphere (plus degradation). It’s not typically a practical issue for the average healthy immune system short term storage.
I don’t have a problem with water based solutions sitting against the plunger… not a fan of doing it with oil based.
Exposing the needle to atmosphere, drawing the solution, then storing it for a period of time before inserting it in the body is a contamination vector. So is the needle exposing the medication to atmosphere (plus degradation). It’s not typically a practical issue for the average healthy immune system short term storage.
Killswitch97
GLP-1 Novice
🚫No Source Discussion🚫
Thanks for all the info guys. I’ll just take a few extra minutes to prep each evening.
Foggy-Hollow
GLP-1 Enthusiast
Mmm yessss pensssss…. Come over to the dark side!
Seriously, I love mine. Peppens has some beautiful product. Especially with water based, it’s 10/10. My oil based it isn’t quite as easy/nice but I think I need to go up a gauge or two. Water based I’m not looking back.
