308fan
GLP-1 Apprentice
Anyone use Prostamax for BHP? I would like to hear about your experience using this. I take Flomax daily and it works ok but I have some days when it needs more help. I would love a long term solution for this. Thanks!
Prostamax
- Thread starter 308fan
- Start date
Researcher6076
GLP-1 Apprentice
Me to. I just recirved a kit and will start it shortly.
dndgeek
GLP-1 Apprentice
I have been using it for about a week now and I will say my symptoms are the best they have been in months. I need a longer period of time before I really give it the hell yeah thumbs up but I am cautiously hopeful its making a difference. I also am looking into starting vesilute.
where did you order yours from?
Researcher6076
GLP-1 Apprentice
Uther.
Researcher6076
GLP-1 Apprentice
MTSpace
GLP-1 Enthusiast
Very interested in your results, dosage, and protocol.
dndgeek
GLP-1 Apprentice
1mg daily I haven't decided how long my cycle length is quite yet. I have seen protocols online for 20days-4months. But I will at least finish out the month and see where my symptoms are at. I have been doing subq injections but I am going to try IM deltoid injections for the next week and see if I perceive a difference. I had a PSA exam a week before starting with another one scheduled right at a month after starting so I will get to see if it makes any difference there(not sure if I expect it to or not).
While researching prostamax I ran into this article talking about vesilute so now I want to add it in as well. Uther has both and I will probably put in an order tonight, i bought a couple single vials of prostamax from a domestic site to try but not enough to last long term.
Right now I am still in the throwing crap at the walls and see what sticks phase so if you guys run into any better sources of info please share and I will check in and let you know in a week how this is going for me.
Vesilute
peptidescalculator.com
Prostamax
pep-pedia.org
peptidedosages.com
peptidescalculator.com
While researching prostamax I ran into this article talking about vesilute so now I want to add it in as well. Uther has both and I will probably put in an order tonight, i bought a couple single vials of prostamax from a domestic site to try but not enough to last long term.
Right now I am still in the throwing crap at the walls and see what sticks phase so if you guys run into any better sources of info please share and I will check in and let you know in a week how this is going for me.
Vesilute
Peptide Calculator | Free & Accurate Tool for Dosage & Reconstitution
Accurate tool for peptide dosage & reconstitution. Calculate doses instantly.
Prostamax
Prostamax - Dosing, Side Effects, Stacking & Research | Pep-Pedia
Prostamax (Lys-Glu-Asp-Pro/KEDP) is a synthetic tetrapeptide bioregulator from the Khavinson peptide family that demonstrates prostate-specific tissue effect...
pep-pedia.org
Prostamax Dosage Protocol | PeptideDosages.com
Complete Prostamax dosage protocol for the 20 mg vial. Covers reconstitution steps, injection dosing schedule, and prostate peptide research cycle guidelines.
peptidedosages.com
Peptide Calculator | Free & Accurate Tool for Dosage & Reconstitution
Accurate tool for peptide dosage & reconstitution. Calculate doses instantly.
Researcher6076
GLP-1 Apprentice
One more question. Did you pause all other peptides while you are doing prostamax? Some advice is to pause...
dndgeek
GLP-1 Apprentice
I actually didn't see that, I am on a pretty light stack currently just reta and DSIP.
Researcher6076
GLP-1 Apprentice
For sure no reason to pause Glp-1s. They operate on completely different pathways. I'm stacking 8 daily peptides, I might decide to pause some. Not sure. The biology behind Prostamax doesn't seem to require it, but the Khavinson bioregulator peptides are a little handwavey, so it's hard to know. I am not tryobe negative. I believe in Epitalon and Thymalin for sure, just the biological mechanisms are scientifically vague at best.
Hi,
I just completed my 3rd cycle.
1st cycle was in October 2025 -> 2mg daily per 20days
2nd cycle Jenuary 2026 -> 1mg daily per 20days
3rd cycle April 2026 -> 1mg daily per 20days
I had some benefit with my pissing flow, that's the better benefit I had, I decide to used it also in order to reduce my PSA level, but I got a partial benefit. The PSA initial value was 5.9ng/ml and after the second cycle it was 4.9 ng/ml
I just completed my 3rd cycle.
1st cycle was in October 2025 -> 2mg daily per 20days
2nd cycle Jenuary 2026 -> 1mg daily per 20days
3rd cycle April 2026 -> 1mg daily per 20days
I had some benefit with my pissing flow, that's the better benefit I had, I decide to used it also in order to reduce my PSA level, but I got a partial benefit. The PSA initial value was 5.9ng/ml and after the second cycle it was 4.9 ng/ml
Researcher6076
GLP-1 Apprentice
I've been diving deeper into Prostamax. I found some interesting stuff. The ONLY Prostamax doses ever discussed in the IBG/Khavinson research are oral, NEVER SUBQ. They created this and did all the research on it, and they only used it as an oral capsule. Their oral dose was 100 mcg - 800 mcg. My head is exploding. Not sure what to do with this information.
IBG states that cytogens (organ‑specific peptide complexes) like Prostamax are orally bioavailable because: they are absorbed as short fragments!
IBG claims that cytogens like Prostamax are broken into short active fragments that:
Based on this information I think I need to consider finding oral Prostamax.
Thoughts?
IBG states that cytogens (organ‑specific peptide complexes) like Prostamax are orally bioavailable because: they are absorbed as short fragments!
IBG claims that cytogens like Prostamax are broken into short active fragments that:
- Survive digestion
- Enter circulation
- Reach target tissues
- Bind DNA promoter regions (IBG’s proposed mechanism)
Based on this information I think I need to consider finding oral Prostamax.
Thoughts?
lessthanhalf
GLP-1 Specialist
Any unmodified peptide will get shredded in very short periods of time in the gut or in the bloodstream, and that includes very short peptide sequences or longer ones. Most endogenous peptides used as signalling molecules such as GLP-1 and the hundreds of others, have modifications at one end to improve stability but usually have very short half lives of minutes. And this applies to most of the peptides you can buy from china. The body does use these molecules for signalling despite only lasting minutes, but it only works because it can keep producing them for long periods of time, and because they typically are effective at ridiculously tiny concentrations of nanomol/litre, whereas administering peptides by continuous infusion is not exactly practical.
The only reason GLP drugs last a week is they are modified to stop peptidases ( enzymes that cut up peptides ) from working on them as well , and have a big long fat molecule stuck to them, so they get attatched to albumin proteins in the blood which also protects them from being degraded or being removed by the kidneys ( which will filter out just about any peptide fairly quickly )
So both the gut and the blood are full of peptide crunching enzymes, that will destroy peptides fairly quickly. A lot of the doses of peptides used are higher by a factor of 100 or 1000 than naturally occurring levels so it is possible they still have effects by short high intensity pulses, even if it is for a short time.
There is no real way to control this process, presumably some sequences are broken up more quickly than others, but di and tri peptides will still be destroyed quite quickly. I am in general a bit skeptical of the bioregulator research, there is at least some actual human testing at least of some of them , but all being done in one place by one set of people, is not the ideal open, transparent , easily critiqued and replicated process, that produces really reliable research, and very very little of that research has been confirmed by outside replication. That kind of insular research environment can produce some bad research, and unless someone outside does the same experiments and get the same or different results there is no way to know.
I just cannot see how a peptide could be designed to work via its broken up fragments, where most of the breaks would be random, leading to a pile of short , short lived peptide bits that were of random lengths and effects or non effects if injected.
If given orally, then most of any protein or peptide is going to be broken down to individual amino acids before being absorbed, with maybe a few short 2 or 3 peptide bits getting through. But every day you eat thousands of different proteins, that are then broken down into extremely high numbers of random length peptide sequences maybe 10 to the power of 20 different ones. I fail to see how that orally consumed peptide is any different to the ones in food.
There are a very few short peptides that are resistant to gut degradation, that the body uses as antimicrobial agents like kpv or bpc. They still get degraded, but more slowly so there is a chance to have an effect before they are ripped apart. This is the case with KPV ( 3 amino acids ) which has some evidence it works for colitis and is fairly resistant to being degraded, but if given orally it still does not make it to the colon where it would be needed to fix colitis, which is why it is not used and most of the research is about combining it with something else or encapsulating it to improve its survival in the gut
The only reason GLP drugs last a week is they are modified to stop peptidases ( enzymes that cut up peptides ) from working on them as well , and have a big long fat molecule stuck to them, so they get attatched to albumin proteins in the blood which also protects them from being degraded or being removed by the kidneys ( which will filter out just about any peptide fairly quickly )
So both the gut and the blood are full of peptide crunching enzymes, that will destroy peptides fairly quickly. A lot of the doses of peptides used are higher by a factor of 100 or 1000 than naturally occurring levels so it is possible they still have effects by short high intensity pulses, even if it is for a short time.
There is no real way to control this process, presumably some sequences are broken up more quickly than others, but di and tri peptides will still be destroyed quite quickly. I am in general a bit skeptical of the bioregulator research, there is at least some actual human testing at least of some of them , but all being done in one place by one set of people, is not the ideal open, transparent , easily critiqued and replicated process, that produces really reliable research, and very very little of that research has been confirmed by outside replication. That kind of insular research environment can produce some bad research, and unless someone outside does the same experiments and get the same or different results there is no way to know.
I just cannot see how a peptide could be designed to work via its broken up fragments, where most of the breaks would be random, leading to a pile of short , short lived peptide bits that were of random lengths and effects or non effects if injected.
If given orally, then most of any protein or peptide is going to be broken down to individual amino acids before being absorbed, with maybe a few short 2 or 3 peptide bits getting through. But every day you eat thousands of different proteins, that are then broken down into extremely high numbers of random length peptide sequences maybe 10 to the power of 20 different ones. I fail to see how that orally consumed peptide is any different to the ones in food.
There are a very few short peptides that are resistant to gut degradation, that the body uses as antimicrobial agents like kpv or bpc. They still get degraded, but more slowly so there is a chance to have an effect before they are ripped apart. This is the case with KPV ( 3 amino acids ) which has some evidence it works for colitis and is fairly resistant to being degraded, but if given orally it still does not make it to the colon where it would be needed to fix colitis, which is why it is not used and most of the research is about combining it with something else or encapsulating it to improve its survival in the gut
Researcher6076
GLP-1 Apprentice
I 100% agree with the weakness of the evidence for efficacy for all the reasons you mention. What's remarkable to me is that somehow we are injecting something that was developed as oral therapy. That takes the evidence scope to a much lower level.
dndgeek
GLP-1 Apprentice
Its been about 3 weeks now and my urinary symptoms have remained in a really good spot. My flow is pretty decent my ability to hold my urine and not have to try and go to sleep on a completely empty bladder(probably the symptom that affected my life the worst) is gone, I only need to pee 2 or 3 times a day. I was on flomax alone for months and never received any relief like this. I dont know if its the prostamax or not but all I can say is I hope it continues. I get my vesilute shipment today and plan to add it in as well and see if my flow gets any better(but its already good enough to live with comfortably). I get my PSA rechecked and have a meeting with the urologist first week of June.
Current Prostate stack from the last month
Flomax Daily
1mg of prostamax daily
Current Prostate stack from the last month
Flomax Daily
1mg of prostamax daily
Researcher6076
GLP-1 Apprentice
TY so much for the update. When the human data is so thin having these kinds of reports is really useful.
Lloyd
GLP-1 Novice
🚫No Source Discussion🚫
I have BPH, I was on flomax, it didn't seem to help, I been doing some research online and found supplements and a discussion about Prostamax. I'm glad you guys are sharing about this. I found a US supplier and got a vial to try. I had a hard time finding a supplier mentioned above. The information shared here has been very helpful. Thank you.
Lloyd
GLP-1 Novice
🚫No Source Discussion🚫
I'm not sure if it understood correctly so I would love some feedback back on the subject of growth hormone enhancing peptides and prostamax. From what I understood, prostamax works to prevent continued growth of the prostate by reducing growth hormone activity, and if that is correct, would taking growth hormone enhancing peptide counteract what we are trying to do with prostamax?
Researcher6076
GLP-1 Apprentice
Supper complicated question. GH secretagogues don’t arbitrarily make things grow. They enhance the body's own ability to recover, and recovery is growth adjacent. If things are working right in the body GH won’t casuse BPH or cancer.
But, if tumors are present, like cancer, the effects GH marshals, like angiogenesis, can make them worse. That’s why cancer or tumors are strict contraindications for taking GH secretagogues.
BPH is non-cancerous hyperplasia, and IGF-1 (that’s what GH secretagogues stimulate) is directly involved in driving hyperplasia. Elevated IGF-1 cannot cause hyperplasia, but if hyperplasia is present, like in BPH, it can, probably will, make it a worse.
How much worse, or even if it is noticeably worse, is, however, just a guess. We have no actual human data to guide us. So, what’s more important to you, the benefits you are getting from GH secretagogues, or the avoiding worse BPH symptoms?
But, if tumors are present, like cancer, the effects GH marshals, like angiogenesis, can make them worse. That’s why cancer or tumors are strict contraindications for taking GH secretagogues.
BPH is non-cancerous hyperplasia, and IGF-1 (that’s what GH secretagogues stimulate) is directly involved in driving hyperplasia. Elevated IGF-1 cannot cause hyperplasia, but if hyperplasia is present, like in BPH, it can, probably will, make it a worse.
How much worse, or even if it is noticeably worse, is, however, just a guess. We have no actual human data to guide us. So, what’s more important to you, the benefits you are getting from GH secretagogues, or the avoiding worse BPH symptoms?
dndgeek
GLP-1 Apprentice
Another update, all my urinary symptoms have stayed in a good place if not improved slightly in the week since I added vesilute. But the huge deal is that I got my PSA back from a blood test this morning at 4.1ng/ML, 6 weeks ago before adding prostamax I was at 6.25ng/ML
KYRivianMan
GLP-1 Apprentice
Which vendor were you able to order Prostamax? I use to get from Uther. Are they still the vendor of choice ?
Florus2026
GLP-1 Apprentice
I see it on the LN Peptide Catalogue, they have most of those (20MG kit - 95 USD). It is not part of my current order with them, not sure if it is in stock. I have only just received my first order from them, I cannot say anything about their general quality for now.
