Question about weight loss on Reta / GLP-1

[Kyli]

Hey Everyone,

I need a little bit help. Long story short (the long story you can find in my introduction), I'm 178 and my SW was about 145kg. CW is 140kg. Currently I'm in my third week with Reta. I was taking 1mg 2x a Week and the last two injections I increased to 1.5mg, the last injection was 2 days ago. And according to my calculation, the active amount of Reta is currently 3mg.

And with Reta I'm taking 5-Amino-1MQ and SS-31.

Now to my question. On 1mg I sometimes got hunger again. Now on 1.5mg everything seems to be fine. But what I don't understand is the effect of Reta. How people loose wight. Because if something is tasty it's pure will power not to eat it.

What I don't understand is, people say to titrate slowly. But why? If according to the studies most patients started to lose weight in the 2nd or even 3rd month. As far as I understand, even the Glucagon Recepterors are not triggered at a dose below about 4mg, because Reta can dock to the receptors but it's not enough to get the liver start working and cleaning the fat from it.

You know, I compared to the SW I now lost about 5kg. But I'm sure most of it was water, because of the inflammations that are now mostly gone. I'm sure it wasn't fat, that melted.

And currently I'm some kind of stuck. I read everything I can get my hand on. But I don't understand, why in the studies people start loosing the weight, when they were at 4-6-8mg a week. So around 5-10mg on active substance in Body. Than I saw here in the forum, that people are stacking Cagri on top. But according to my research it can cause Gastroparesis.

You know, I started very motivated in the journey. Bur currently I'm some kind confused. I want more in a shorter period of time.

 

[FLglpguy]

It's a marathon, not a race. You will make yourself very sick if you up the dose too soon. As far as will power...you won't have the desire to eat the foods you liked before starting this journey. It won't take any will power at all. Stay the course. Titrate up as scheduled and don't overthink it or overdo it.

I'm on week 5 of Tirz. I have lost 26lbs and feel GREAT! No food noise, inflammation is gone, my skin is clearer, I'm better focused at work and my joint pain has even lessened.

I also take B12, Magnesium Malate, Whey, Casein protein powder and have been eating soups, raw veggies and fresh fruits, nuts, fiber and nut bars and salads. Loving the new foods and not missing the fried junk that clogged me up from head to toe. I don't even think of burgers, or meat filled meals or sweats or treats and none of these foods are even in my home.

 

[Rezwalker]

First thing first its not a miracle weight loss drug (but almost )
You still need to train and diet
reta will help with binge eating at night and usually over eat at every meal
you will get full quicker and stay full longer

but you wont lose 50 pound in 3 months unless your 300lbs + and stop eating drasticly

you need to eat in a deficit and train and do your 12k steps

GLP1 will help mitigate your bing eating thats it
forget the glucacon etc
dont split dose reta you will only get used to it faster
single dose will do more appetite suppresion vs split

Even if its the tastiest treat in front of you reta will help the urge to eat it
always remember the prize and the end
Slim and healthy
if you dont train and eat you will look like Hollywood star atm ultra skelleton slim and look like your about the die

 

[rmhla]

Retatrutide sides can be awful to some like
Aladonia which is basically "goosebumps" cold feeling down your legs, arms, etc. While some like that or dont mind it many hate it.
Then there rapid increase in heart beat (not blood pressure)
So...
By taking your time titrating up you see what you are capable of. Why take 8mg if it works at 3mg... right... but yes most notice more of a difference at 8mg spilt into 4mg shots 2 x weekly.

Also by using other peptides at the same time, you dont actually know which ones working best. Food for thought here..

Like other posters here above its not a race, you spent how many years pigging out with no worries, so why rush losing it all so fast you end up needing a grocery cart to carry your extra skin behind... yup happens allot..

Healthy is 1.2lb to 2lb month as it will stay off then as too rapid weight loss almost always comes back.

Dont keep up with the Jones, do your own thing be patient and just because the scale isnt moving doesnt mean it isn't working...

As for food noise you can drop the other peptides your taking for example and look into Cagrilintide for example..

Also remeber higher doses of Retatrutide come with loss of muscle though not 100% proven in everyone theres more and.morw studies coming out to this effect.


Lastly just because Glps make it easy, its mucb better to excersie even if atleast walking deliberately not counting day to day bill payments or grocery stores runs. Actually out walking for 30mins to an hour.
Eatting also plays a big role reta hates to much fat and you'll feel it, often not talked about.

 

[quicksilver80]

Going too fast can lock up your gastric. Either none at all or everything all the time. I had constipation but some of my friends could have pooped through a screen door and left it spotless. Then comes the whole pancreatitis and other secondary issues from that. Yeah. Be careful buddy.

 

[Kyli]

Thank you for your advice, everyone.
The idea behind stacking the SS-31 and 5-Amino-1MQ was on one hand to fix broken mitochondria and increase the energy level.

And yes, I'm doing sport. I have three dogs. So I walk every day for about 2 hours + the training with the dog. And I also start weightlifting.

I already looked into Cagrilintide. But I don't get it's meaning in combination with Reta. Why it should be better to stack it on top instead of increasing the dosage?

I'm on week 5 of Tirz. I have lost 26lbs and feel GREAT! No food noise, inflammation is gone, my skin is clearer, I'm better focused at work and my joint pain has even lessened.

May I ask, with what kind of dose you are currently in Week 5?

forget the glucacon etc

Why? As I understand, this is the factor, what makes the difference to Trizapetide. It's increasing the total energy, and prevent the metabolism adaptation to a lower callory level.

 

[FLglpguy]

Thank you for your advice, everyone.
The idea behind stacking the SS-31 and 5-Amino-1MQ was on one hand to fix broken mitochondria and increase the energy level.

And yes, I'm doing sport. I have three dogs. So I walk every day for about 2 hours + the training with the dog. And I also start weightlifting.

I already looked into Cagrilintide. But I don't get it's meaning in combination with Reta. Why it should be better to stack it on top instead of increasing the dosage?


May I ask, with what kind of dose you are currently in Week 5?


Why? As I understand, this is the factor, what makes the difference to Trizapetide. It's increasing the total energy, and prevent the metabolism adaptation to a lower callory level.

I'm currently at .50 dose of Tirz. It titrates up every 4wks. I just took shot 6 on Wednesday. I chose Tirz because I want the best appetite suppression. I started at 386lbs. - I'm at 360lbs right now and I'm 6'2" and 55yrs old. I have a long road in front of me to get to my GW of 215lbs, so I wanted as much appetite suppression as possible.

 

[Rezwalker]

Thank you for your advice, everyone.
The idea behind stacking the SS-31 and 5-Amino-1MQ was on one hand to fix broken mitochondria and increase the energy level.

And yes, I'm doing sport. I have three dogs. So I walk every day for about 2 hours + the training with the dog. And I also start weightlifting.

I already looked into Cagrilintide. But I don't get it's meaning in combination with Reta. Why it should be better to stack it on top instead of increasing the dosage?


May I ask, with what kind of dose you are currently in Week 5?


Why? As I understand, this is the factor, what makes the difference to Trizapetide. It's increasing the total energy, and prevent the metabolism adaptation to a lower callory level.

all that mather is how can you hold your diet without binging its there the reta/tirz/sema/etc that shine
steady diet will win over everything or any compound
you will get the glucagon over time but you can acheive fatloss with it
its just a +

 

[NagChamp]

When I was making decisions about which route to choose (GLP vs Reta) I went with GLP (Tirz) because my main aim was to quash food noise, knowing that positive results would flow from this. Reta is known for not managing food noise as effectively as Tirz. You might want to consider either switching or stacking both if food noise is an issue for you.

That said, FLglpguy is right, this is a marathon and not a sprint. Don't let the BS you've seen on Reddit forums trick you into thinking that you can get ripped in 3 months.

 

[gimmeshelter]

You want food intake or eating adherence meaning reta will allow you to be indifferent about most food like wasted cals of snacks and sugar drinks. You don't want to feel sick. I'm 6 5' started at 240lbs. Did .5ml for a month , now on week 10 on 1.8ml. BUT.......

I weigh food to the gram / hard cardio 3 times a week / high protein diet / gym 4 days a week.

I feel normal w my reta dose I can eat w the family I can also skip a meal if I want or eat more getting ready for cardio .