Reconstituted Reta - what's the latest on shelf-life?

[mlke6]

And thats why you dont buy 120 mg Tirza
Recomendation is of course to buy vials that lasts only the time period mentioned

I ended up with a kit of those. If I ever get to them, in 5 to 6 years maybe, I plan on splitting into smaller vials and freezing.

 

[CNCCurrency]

I ended up with a kit of those. If I ever get to them, in 5 to 6 years maybe, I plan on splitting into smaller vials and freezing.

I am not really comfortable freezing reconstituted. Are there any references on freezing?

 

[tubby]

I am not really comfortable freezing reconstituted. Are there any references on freezing?

Don't have a reference handy, but it's going to vary by peptide, with some being more stable than others, so what's true of tirzepatide isn't going to be true for peptides in general. From what I've read, tirzepatide is pretty stable in that regard (freezing after reconstituting), but obviously you wouldn't want to do it that way unless you had a good reason to.

I'd imagine the thought process is that this is more of preparing for a doomsday scenario. If after nuclear war breaks out between China and the US and OP is in one of the regions to survive the initial destruction, somehow obesity is still prevalent, and it's impossible to source tirzepatide, those vials will be worth their weight in gold.

Or in 5 years US customs starts using AI robots to inspect every package 100% of the time and short of smuggling the vials into the country by shoving them up your butt before travelling the gray market ceases to exist.

Most likely neither of those scenarios play out and grays continue to flow cheaply, but in that 1% edge case, you'll sure be kicking yourself that you didn't stock up when you had the chance! 😉

 

[indolent]

I am not really comfortable freezing reconstituted. Are there any references on freezing?

Do a search to find existing discussions on this.

 

[Lyophilized]

I am not really comfortable freezing reconstituted. Are there any references on freezing?

One freezing cycle with reconstituted Tirz will not be a problem...

And if I tell you that in all the samples I already analyzed I find PFAS in all you them and no one discuss it here in the forum?

The analysis I saw from Jano LCMS are only targeted compounds like Tirz or Reta
I never saw a TIC chromatogram from a sample and try to identify unknown peaks..

Most of the people, after a Jano testing, with a "good result" feel comfortable to inject but the truth is that no one knows the amount of unknown compounds that are really there

So, regarding freezing reconstituted Tirz, believe me, It will be the least of the real problems/risks
Just my opinion

 

[tubby]

And if I tell you that in all the samples I already analyzed I find PFAS in all you them and no one discuss it here in the forum?

Are you saying you identified PFAS in some samples, or are you asking the hypothetical of what people would say if PFAS were identified at any significant concentration?

 

[Lyophilized]

Are you saying you identified PFAS in some samples, or are you asking the hypothetical of what people would say if PFAS were identified at any significant concentration?

I identified.
The concentration is small... But it's there..
It's was not PFOA.
But everything that you inject with PFAS will normally stay in body for quite some time. They are very stable and difficult to break
I don't know were could be the source... if it comes from the rubber seal (normally rubber are not suppose to have PFAS) or from the manufacture process (tubbings mostly in contact with solvents during synthesis)

 

[Sid the SeaGull]

Thanx I'm somewhat concerned regarding PFAS. However mindful that they are arguably difficult to get away from in many environments.

More information would be helpful and I'm sure that it will come out over time with further testing