octopusthorpe
GLP-1 Apprentice
50 y/o, 5'10", lost 160lb back in 2016 via low-carb diet, progressive overload strength training, and hiking.
Maintained that weight loss until perimenopause hit in late 2024 - gained almost 20lb in a year despite no changes to diet or training.
Started HRT (estradiol patch and low-dose test-c) which helped with everything but the creeping weight gain.
Weight went from 140-ish to between 157-162lb and would not budge despite all my tried and true fat loss approaches.
Five and a half weeks on reta and I'm down 18.6lb (1mg/week, split into two 0.5 doses) with no impacts to my ability to lift (max bench 130lb, max squat 205lb and max deadlift 305lb) although my weekly hikes took a hit - I typically do anywhere between 20-30 miles every Saturday with around 2k feet elevation gain but recovery from these has taken a dip, so I've been keeping it around 12-15 miles every other week. Light indoor bike for non-hiking days.
RHR and HRV only very mildly impacted (RHR went from 45-50bpm to 51-54bpm). Sleep could be better (still averaging around 6-7 hours per night but the waking up at 4am kinda sucks).
Protein intake: around 160g/day (which is typical for me).
Now that I'm down to 144 I may take the dose down a bit as I don't want to lose too much, just amazed at just how effective this is.

Maintained that weight loss until perimenopause hit in late 2024 - gained almost 20lb in a year despite no changes to diet or training.
Started HRT (estradiol patch and low-dose test-c) which helped with everything but the creeping weight gain.
Weight went from 140-ish to between 157-162lb and would not budge despite all my tried and true fat loss approaches.
Five and a half weeks on reta and I'm down 18.6lb (1mg/week, split into two 0.5 doses) with no impacts to my ability to lift (max bench 130lb, max squat 205lb and max deadlift 305lb) although my weekly hikes took a hit - I typically do anywhere between 20-30 miles every Saturday with around 2k feet elevation gain but recovery from these has taken a dip, so I've been keeping it around 12-15 miles every other week. Light indoor bike for non-hiking days.
RHR and HRV only very mildly impacted (RHR went from 45-50bpm to 51-54bpm). Sleep could be better (still averaging around 6-7 hours per night but the waking up at 4am kinda sucks).
Protein intake: around 160g/day (which is typical for me).
Now that I'm down to 144 I may take the dose down a bit as I don't want to lose too much, just amazed at just how effective this is.
