Reta + Tesa combination

[olehandro]

What are your thoughts on the combination of Reta and Teza?
Has anyone tested this?

 

[Lovedog100]

I do both, If you can afford both it has worked very well for me. Tesamorlin is more expensive monthly than Reta. My weight loss has accelerated. I hate the daily injections though. I'd like to do two or three a week of twice as much. I haven't talked with anyone that has tried it though.

 

[Chopper]

Anecdotaly the Two worked together very well for Visceral fat/flattering stomach area. Wife still on this combo working well. I still have 40-50 to lose for goal but Tesa, then gh have helped me not lose as much muscle with the fat as reported by a bmi scale as well as my Samsung watch. I was originally losing a decent amount of muscle with fat on tirzepatide, then added Reta and backed off on Tirzepatide. That slowed muscle loss dow by those metrics (albeit not necessarily accurate). Adding Tesa actually showed slight muscle gain. Stopped Tesa and started low dose gh muscle seems to react about the same with slightly more water retention, and oddly slightly better glucose control than with Tesa.
The latteray just be a product of better overall health than Tesa vs gh. I may experiment with Tesa again once at goal to see if that remains true for me of if the opposite is true at that point.

 

[Calm Logic]

and oddly slightly better glucose control than with Tesa.

I think @hexagonal had the same experience with HGH vs. tesa, possibly more so.

 

[Chopper]

I think @hexagonal had the same experience with HGH vs. tesa, possibly more so.

Good as I thought I was crazy because everything I read said HGH would raise it more, but I wonder if that's because people get the dosage too high?

 

[Calm Logic]

HGH can burn more fat overall than tesa, so that could be one reason maybe. And:

If your IGF-1 levels get high enough from the 2 IU of HGH, the "insulin-like" effects of the IGF-1 can sometimes override the "anti-insulin" effects of the GH itself, leading to surprisingly stable blood sugar.

Nitric Oxide (NO) is a massive factor in how your body handles sugar, and HGH has a direct, positive influence on it that Tesamorelin may not match as effectively.

If 2 IU of HGH helps you sleep significantly better than 2 mg of Tesamorelin, your morning cortisol levels will be lower. Lower cortisol = less sugar dumped by the liver in the morning (the "Dawn Phenomenon"). For some, the metabolic benefit of better sleep outweighs the direct impact of the HGH.

If HGH boosts your T3 levels more effectively than Tesamorelin, your basal metabolic rate increases. You burn more energy just sitting there, which can help "clear" the extra glucose HGH is creating.

The above is basically a love letter to HGH, haha. I did buy some tesa though as a break from HGH.

 

[CNCCurrency]

Good as I thought I was crazy because everything I read said HGH would raise it more, but I wonder if that's because people get the dosage too high?

yes, its the main reason. Start low and increase after a month or two.

 

[DunningKruger]

What are your thoughts on the combination of Reta and Teza?
Has anyone tested this?

Love the pairing. Highly recommend for body recomposition.

(Small Female)
9 weeks: 17 lb loss
Fat Mass: -9.0%
Lean Mass: +8.6%

Visible muscle gain, noticeable strength gain, and ease with resistance training. I keep both at the starting dose (Reta 2mg, Tesa 1mg) and have never needed to increase over the 9 weeks. I actually decreased the Reta for a couple of weeks to 1mg and still saw fat loss and strength gains, albeit slower. They helped me get to goal while sparing muscle. I can't recommend them enough.

 

[Lovedog100]

Good as I thought I was crazy because everything I read said HGH would raise it more, but I wonder if that's because people get the dosage too high?

Try looking into HGH fragment 176-191. It does not raise glucose that same way HGH (Somatropin) does. 176-191 also doesn't have the muscle building proprieties as regular HGH, yet does burn the fat. Depending if you want loss of fat, muscle building, or both should be your guide as to which one to pick. One will raise Glucose, and the other leaves it unaffected. Those of us over 50 should probably stick with HGH 176-191

 

[Calm Logic]

Those of us over 50 should probably stick with HGH 176-191

What about HGH for preventing muscle loss while on GLPs?

GLPs may also help prevent glucose/insulin issues on HGH, as may Jardiance or even supplements like berberine. Testing also helps, like I would get fasting insulin (and C-Peptide) done in addition to IGF-1 and basic bloodwork like CMP (to get glucose) and an A1C every now and then.

 

[Lovedog100]

What about HGH for preventing muscle loss while on GLPs?

GLPs may also help prevent glucose/insulin issues on HGH, as may Jardiance or even supplements like berberine. Testing also helps, like I would get fasting insulin (and C-Peptide) done in addition to IGF-1 and basic bloodwork like CMP (to get glucose) and an A1C every now and then.

It's just my opinion, which has been influenced by others. I prefer Tesamorlin to HGH. I'm not 30 years old though. Tesamorlin stimulates some HGH release while adding to weight loss. I have stopped taking Jardiance since stacking the two. I'm personally getting better results from Tesamorlin than jardiance. Not taking the Jardiance is paying for the Tesamorlin. That's a win win for me.
While I have berberine, I haven't tried it yet. I do add a teaspoon of ceylon cinnamon to my first cup of coffee in the morning. I started it two weeks before giving up Jardiance. I believe that it's had an effect on helping to keep glucose down. My testing has me believing that I could lower the dose of Metformin as well.

 

[GeraltRedhammer]

Przyjmuję 3 mg Retatrutydu i 1 mg Tesamorelinu z 300 mcg Ipamorelinu raz dziennie – działa synergicznie i wzmacnia działanie Tesy, co jest rzadką sytuacją, gdy 1+1=3.

Ta kombinacja działa u mnie świetnie. Powoli tracę wagę, około 0,5 kg tygodniowo, ale jednocześnie buduję siłę i masę mięśniową. Idealne połączenie dla rekompozycji ciała.

 

[Calm Logic]

Przyjmuję 3 mg Retatrutydu i 1 mg Tesamorelinu z 300 mcg Ipamorelinu raz dziennie – działa synergicznie i wzmacnia działanie Tesy, co jest rzadką sytuacją, gdy 1+1=3.

Ta kombinacja działa u mnie świetnie. Powoli tracę wagę, około 0,5 kg tygodniowo, ale jednocześnie buduję siłę i masę mięśniową. Idealne połączenie dla rekompozycji ciała.

Translation:

I am taking 3 mg of Retatrutide and 1 mg of Tesamorelin with 300 mcg of Ipamorelin once a day—it works synergistically and enhances the effects of the Tesa, which is one of those rare situations where 1 + 1 = 3.

This combination is working great for me. I’m slowly losing weight, about 0.5 kg per week, but at the same time, I’m building strength and muscle mass. It’s the ideal combination for body recomposition.

 

[dirtyharry]

I do both, If you can afford both it has worked very well for me. Tesamorlin is more expensive monthly than Reta. My weight loss has accelerated. I hate the daily injections though. I'd like to do two or three a week of twice as much. I haven't talked with anyone that has tried it though.

"I haven't talked with anyone that has tried it though." I have embraced my new life as a peptide Guinea pig.

 

[UpDownLeftRightAS*]

Works great, especially when you’re close to your goal weight. One thing I can’t stress enough is doing some research on Egrifta dosing (tesamorelin) and the benefits of resistance training, particularly for the abdominal and midsection areas.

Even short sessions help. Try to fit in 15–20 minutes a day of simple combinations ... push-ups, sit-ups, crunches, wall sits, stretching, or whatever movements you can consistently commit to. Consistency matters far more than intensity.

If you’re able to add yoga or Pilates, that can accelerate results significantly by strengthening the core and improving overall muscle engagement.

The key is finding a routine you can realistically stick with every day.

 

[bogardbilla]

Works great, especially when you’re close to your goal weight. One thing I can’t stress enough is doing some research on Egrifta dosing (tesamorelin) and the benefits of resistance training, particularly for the abdominal and midsection areas.

Even short sessions help. Try to fit in 15–20 minutes a day of simple combinations ... push-ups, sit-ups, crunches, wall sits, stretching, or whatever movements you can consistently commit to. Consistency matters far more than intensity.

If you’re able to add yoga or Pilates, that can accelerate results significantly by strengthening the core and improving overall muscle engagement.

The key is finding a routine you can realistically stick with every day.

What's the reasoning behind this claim that one should do resistance training on abdominal and midsection areas? It physically moves the visceral fat around and that helps activating fat loss?