Second month of tirz, first time with reconsituting!

[mintyquinn]

Hello all - so I joined and introduced and then life happened, but I decided to move to tirz from sema due to a friend giving me a stash of 2.5mg for a month. I'm about done with that, and it's working but I think i need at least 5mg tirz now, as I was on 1.7mg sema before. I've been reading online and it sounds like I should maybe go higher than 5mg tirz but I'm slow rolling up, and if 5mg will work well then maybe I can chill there a bit.

My question is - for this next month, i purchased a kit of 20mg vials from nexaph - it was the most affordable I've found so far (and i know there's stuff way way cheaper, but I'm really new to grey and I don't feel comfy using crypto). So I'm hoping this stuff is real and will work. I wanted to check my math on it - if i want 5mg dose, and I have 20 mg vial.....if i use 2 ml bac water into my 20mg vial, is that 4 doses of 5mg? 50 units? i used a calculator and I THINK it makes sense but I feel so unsure of the math because I'm dumb af with numbers.

Also any advice on any of this above is welcome, I'm very nervous about it, esp since I thought I was going to be doing sema for this not tirz! 🙂

 

[indolent]

Welcome! It sounds like you're on a good path, and Nexaph is an excellent choice for you at this stage. Two things:

1. You need to adjust your calculations of how many milligrams are in each vial, based on lab testing of the batch (unless it's within 10% of the nominal mgs). In the case of Nexaph (but not most vendors), I'd be comfortable with the "2nd party" testing which they commissioned. Scan the QR code on the kit box to be linked to the CoA...it might take a week or two for it be produced and linked.
2. Shoot for 20-40 units per dose, aiming for the numbered ticks on your syringes, and use a reverse peptides calculator (linked in my signature; rotate your phone if you don't see it) to do the calculation. Scroll down for mg to mcg converter first. It's much easier to add a non-round amount of bac water--once--at reconstitution time vs trying to gauge weird amounts in an insulin syringe, a few times.

 

[Calm Logic]

I double check everything with AI too.

For example:

Okay, let's redo the math to get a dose between 20 to 40 units on a U-100 insulin syringe. To do this, we'll need to adjust the amount of BAC water you add to your 20mg vial.

First, let's understand what 20-40 units means in terms of milliliters:

• U-100 Insulin Syringe: 100 units = 1 ml
• 20 units: 20 / 100 = 0.2 ml
• 40 units: 40 / 100 = 0.4 ml

So, you want each 5mg dose to be between 0.2ml and 0.4ml.

Now, let's figure out how much BAC water to add to achieve this.

Scenario 1: Aiming for 20 units (0.2 ml) per 5mg dose

If you want 5mg to be 0.2ml, then your concentration needs to be:5mg / 0.2ml = 25mg/ml

To achieve a concentration of 25mg/ml with a 20mg vial, you would add:20mg / 25mg/ml = 0.8 ml of BAC water

• With 0.8ml BAC water:
  
  • Concentration: 20mg / 0.8ml = 25mg/ml
  • Volume for 5mg dose: 5mg / 25mg/ml = 0.2ml
  • Units for 5mg dose (U-100 syringe): 0.2ml * 100 units/ml = 20 units
  • Total doses from vial: 0.8ml (total volume) / 0.2ml (per dose) = 4 doses

Scenario 2: Aiming for 40 units (0.4 ml) per 5mg dose

If you want 5mg to be 0.4ml, then your concentration needs to be:5mg / 0.4ml = 12.5mg/ml

To achieve a concentration of 12.5mg/ml with a 20mg vial, you would add:20mg / 12.5mg/ml = 1.6 ml of BAC water

• With 1.6ml BAC water:
  
  • Concentration: 20mg / 1.6ml = 12.5mg/ml
  • Volume for 5mg dose: 5mg / 12.5mg/ml = 0.4ml
  • Units for 5mg dose (U-100 syringe): 0.4ml * 100 units/ml = 40 units
  • Total doses from vial: 1.6ml (total volume) / 0.4ml (per dose) = 4 doses

Conclusion for 20mg vial, 5mg dose, 20-40 units:

To get a 5mg dose that falls between 20 and 40 units (0.2ml to 0.4ml), you should add between 0.8ml and 1.6ml of BAC water to your 20mg vial.

• If you add 0.8ml of BAC water, each 5mg dose will be 20 units.
• If you add 1.6ml of BAC water, each 5mg dose will be 40 units.

Both scenarios will still give you 4 doses from your 20mg vial. You can choose any amount of BAC water between 0.8ml and 1.6ml, and then calculate the exact units per 5mg dose using the steps above.

 

[mintyquinn]

Welcome! It sounds like you're on a good path, and Nexaph is an excellent choice for you at this stage. Two things:

1. You need to adjust your calculations of how many milligrams are in each vial, based on lab testing of the batch (unless it's within 10% of the nominal mgs). In the case of Nexaph (but not most vendors), I'd be comfortable with the "2nd party" testing which they commissioned. Scan the QR code on the kit box to be linked to the CoA...it might take a week or two for it be produced and linked.
2. Shoot for 20-40 units per dose, aiming for the numbered ticks on your syringes, and use a reverse peptides calculator (linked in my signature; rotate your phone if you don't see it) to do the calculation. Scroll down for mg to mcg converter first. It's much easier to add a non-round amount of bac water--once--at reconstitution time vs trying to gauge weird amounts in an insulin syringe, a few times.

OH MY GOD - the reverse calculator is great. I was definitely getting weirded out by having to make a large draw, esp with how much bigger tirz doses seem to be? So this makes a lot more sense. That said, I am wondering how exact i can be to get the right amount of BAC water, if it's telling me like .84, I don't know if that's easily readable in the syringe when its time to do it? I havent actually done this part yet, so I bought things, just havent opened stuff yet.

 

[mintyquinn]

I double check everything with AI too.

For example:

I didn't even think about using AI for it.....I have avoided AI for many things so I forget it's there as a tool LOL

 

[mintyquinn]

Speaking of the mgs on the tested bastches - so they are a little bit higher than 20mg and there's 3 of them? I wasn't sure how to incorporate that into my dosage. This is from their testing batch:

 

[Calm Logic]

Take the average of the three. But 24 mg in any case really:

Ok, I understand. You have a new vial strength to work with, and you want to use the average of the three listed Tirzepatide measurements from the image.

Let's first calculate the average Tirzepatide amount:

• Tirzepatide measurements: 24.03 mg, 23.88 mg, 23.96 mg
• Average Tirzepatide: (24.03 + 23.88 + 23.96) / 3 = 71.87 / 3 = 23.9567 mg (We'll use approximately 23.96 mg for calculations)

So, your vial contains approximately 23.96 mg of Tirzepatide. Your desired dose is still 5mg, and you want each 5mg dose to be between 20 to 40 units (0.2ml to 0.4ml) on a U-100 insulin syringe.

Let's recalculate the amount of BAC water needed based on this new vial strength.

Scenario 1: Aiming for 20 units (0.2 ml) per 5mg dose

• Desired concentration for a 5mg dose to be 0.2ml: 5mg / 0.2ml = 25mg/ml

To achieve a concentration of 25mg/ml with your 23.96mg vial, you would add:

23.96mg / 25mg/ml = 0.9584 ml of BAC water (approximately 0.96 ml)

• With ~0.96ml BAC water:
  • Concentration: 23.96mg / 0.96ml ≈ 24.96 mg/ml (very close to our target of 25mg/ml)
  • Volume for 5mg dose: 5mg / 24.96mg/ml ≈ 0.2003 ml
  • Units for 5mg dose (U-100 syringe): 0.2003ml * 100 units/ml ≈ 20 units
  • Total doses from vial: 0.96ml (total volume) / 0.2003ml (per dose) ≈ 4.79 doses (You'd get 4 full doses and a partial fifth)

Scenario 2: Aiming for 40 units (0.4 ml) per 5mg dose

• Desired concentration for a 5mg dose to be 0.4ml: 5mg / 0.4ml = 12.5mg/ml

To achieve a concentration of 12.5mg/ml with your 23.96mg vial, you would add:

23.96mg / 12.5mg/ml = 1.9168 ml of BAC water (approximately 1.92 ml)

• With ~1.92ml BAC water:
  • Concentration: 23.96mg / 1.92ml ≈ 12.48 mg/ml (very close to our target of 12.5mg/ml)
  • Volume for 5mg dose: 5mg / 12.48mg/ml ≈ 0.4006 ml
  • Units for 5mg dose (U-100 syringe): 0.4006ml * 100 units/ml ≈ 40 units
  • Total doses from vial: 1.92ml (total volume) / 0.4006ml (per dose) ≈ 4.79 doses (You'd get 4 full doses and a partial fifth)

Conclusion for 23.96mg vial (average), 5mg dose, 20-40 units:

To get a 5mg dose that falls between 20 and 40 units (0.2ml to 0.4ml), you should add between approximately 0.96ml and 1.92ml of BAC water to your vial.

• If you add approximately 0.96ml of BAC water, each 5mg dose will be around 20 units.
• If you add approximately 1.92ml of BAC water, each 5mg dose will be around 40 units.

In both scenarios, you will get approximately 4 full doses and a partial fifth dose from your vial.

 

[indolent]

how exact i can be to get the right amount of BAC water, if it's telling me like .84,

Eyeball it as best you can.

they are a little bit higher than 20mg

20%! That's why the testing is important.