Semax. Works, but not the way I expected.

ultima thule

GLP-1 Enthusiast
Member Since
Mar 25, 2026
Posts
213
Likes Received
435
Location
Ireland
Ireland
Just on the end of the 2nd week on Semax (subq). Started with .5mg the first week, at the second week boosted to 1mg. But it wasn't the best idea. Yesterdays morning right after the shot of 1mg, I was feeling like on the hard core preworkout stuff with a ton of caffeine in it. Kind of brain fvck. Hence today I decided to lower to 750mg and it's much better. But that's what I'm about in this thread. My response to this compound is different than what it supposed to be. So the only sensation regarding Semax for me is a higher energy during the day. Also in the gym I'm a bit like invincible...can workout harder, faster, etc, and feel no fatigue. Do not notice any boost on the focus, better cognitive skills, or memmory etc. Would even say, I'm a bit more distracted recently...in general it's hard for me to say whether I'm happy of Semax or not. On the one hand it is good to be more energetic during the day, and not fatigued after work, when gym is not a chore, but just another easy task of the day. But I wanted to get from it something else. Gonna make it 4 weeks cycle, so it might be changed, but so far I have a mixed feelings.
 
Just on the end of the 2nd week on Semax (subq). Started with .5mg the first week, at the second week boosted to 1mg. But it wasn't the best idea. Yesterdays morning right after the shot of 1mg, I was feeling like on the hard core preworkout stuff with a ton of caffeine in it. Kind of brain fvck. Hence today I decided to lower to 750mg and it's much better. But that's what I'm about in this thread. My response to this compound is different than what it supposed to be. So the only sensation regarding Semax for me is a higher energy during the day. Also in the gym I'm a bit like invincible...can workout harder, faster, etc, and feel no fatigue. Do not notice any boost on the focus, better cognitive skills, or memmory etc. Would even say, I'm a bit more distracted recently...in general it's hard for me to say whether I'm happy of Semax or not. On the one hand it is good to be more energetic during the day, and not fatigued after work, when gym is not a chore, but just another easy task of the day. But I wanted to get from it something else. Gonna make it 4 weeks cycle, so it might be changed, but so far I have a mixed feelings.
So would you say it gave you temporary ADHD type effect where focus worsened but you got a hyperactive energetic state?
 
So would you say it gave you temporary ADHD type effect where focus worsened but you got a hyperactive energetic state?
Maybe not ADHD, that would be exaggeration. After yesterdays shot of 1mg I was feeling realy high. Like I said, a kind of feeling of very strong pre workout, or high amount of caffeine. It just hit instantly after the shot and last for a couple minutes. The rest of the day I was just feeling like having more energy. Didn't get tired. Whole day couldn't wait to finish work to get to the gym. And when I hit the gym, I was flying. Other than that I forgot to add in the first post I could say my mood is better currently. Feeling more relaxed, less stressed. Also finishing today 20 days cycle of Epitalon, but don't think it may have any impact. Tbh do not feel anything special from Epi. So influance of Semax is noticeable, but in a quite confusing manner on my end.
 
I have this type of reaction with Adamax. I am on my second NA cycle and love the stuff. The boost in energy is great but not so much gym energy but talking and focus. I have deep work conversations and the wording of my conversations can surprise me haha. It seem I get good clarity while listening and my responses are higher level. I might try Semax to see the difference as it is cheaper. My second cycle with Selank is proving that I don't respond to it. First cycle was 600mcg NA and this is 1mg daily for 20 days. Adamax is 500mcg NA daily.
 
I have this type of reaction with Adamax. I am on my second NA cycle and love the stuff. The boost in energy is great but not so much gym energy but talking and focus. I have deep work conversations and the wording of my conversations can surprise me haha. It seem I get good clarity while listening and my responses are higher level. I might try Semax to see the difference as it is cheaper. My second cycle with Selank is proving that I don't respond to it. First cycle was 600mcg NA and this is 1mg daily for 20 days. Adamax is 500mcg NA daily.
Well so I miss that kind of focus so far, but the rest of symptoms you describe are quite similar. It is my second week now on that, so maybe it will develope in the focus, sharpness way furthermore...
 
Well so I miss that kind of focus so far, but the rest of symptoms you describe are quite similar. It is my second week now on that, so maybe it will develope in the focus, sharpness way furthermore...
Worth noting that you are taking Semax and subq, I ma with Adamaz with nasal spray. Adamax is considered a stronger version but the effects should be similar. We are all different though 😉
Some people have zero effects like myself with Selank. I also believe after reading a fair amount of anecdotal feedback, these type of peptides can aid people who need to the support. Selank is sometimes used for people who find it difficult to destress or have calm in the later afternoon/evenings. I thought I did but changes are, I am able to do this and not require the support if that makes sense. Good luck on your Semax journey. If you find you like it and it makes a difference, read more then on Adamax.
 
I did a one month cycle of both Semax and Selank. I really like Semax. I do that one in the morning and Selank in the evening. For me, Semax is the much better peptide. It gives me energy, but at the same time, gives me focus, clarity, and calmness. Selank is weird stuff in that I don't really know anything to compare it with. It has an anxiolytic effect for sure, but it's an odd effect that I cannot really describe.

I'll run another cycle of both after I finish my break. I'm doing Oxytocin in the meantime and my reaction to it is sort of unexpected. I do it afternoon and for about the first 7 days, all I felt off it is a strong facial flushing for 5-10 minutes. If you are having constipation on a GLP-1, it also helps with that. But after a little more than a week, I started getting a very noticeable boost in my overall mood. It doesn't last every long, like 20-30 minutes after injection until you go to bed, but in general, gone the next morning.

Semax is now my go to for mental well being, just not sure if taking it all the time is OK, so I am cycling. Don't want to burn out my dopamine receptors. But I bet it will help with the GLP-1 blahs, mild anhedonia.
 
Have cycled blends of semax/selank at 500mcg once a day for 2 months. Was iffy on the results. Switched to doing them individually at 750mcg daily. Still iffy on results. So genius me ordered a kit of each but the NA versions and gonna give that a rip in about another week. I will say when I stop it for a few days then go back to it it does give me an almost flushing feeling. I’m still holding hope because of that that maybe it’s working just not as much as I was hoping for. Maybe the NA versions will have more effect. If not I’m gonna write it off as not for me.
 
Have cycled blends of semax/selank at 500mcg once a day for 2 months. Was iffy on the results. Switched to doing them individually at 750mcg daily. Still iffy on results. So genius me ordered a kit of each but the NA versions and gonna give that a rip in about another week. I will say when I stop it for a few days then go back to it it does give me an almost flushing feeling. I’m still holding hope because of that that maybe it’s working just not as much as I was hoping for. Maybe the NA versions will have more effect. If not I’m gonna write it off as not for me.
I do 500mcg of both. I might move up to 750mcg or so of Semax. I'm only trying the Selank again to see if I think it is worth continuing. I'm injecting and have never tried nasal. I have a source now, but since pinning works, I'll stick with it for now because I already have my new batch.
 
I do 500mcg of both. I might move up to 750mcg or so of Semax. I'm only trying the Selank again to see if I think it is worth continuing. I'm injecting and have never tried nasal. I have a source now, but since pinning works, I'll stick with it for now because I already have my new batch.
I see some protocols get up to dang near a gram a day or more with multiple sub q’s for semax. I’ve never went the nasal route either. Something about sub q feels right to me.
 
Just on the end of the 2nd week on Semax (subq). Started with .5mg the first week, at the second week boosted to 1mg. But it wasn't the best idea. Yesterdays morning right after the shot of 1mg, I was feeling like on the hard core preworkout stuff with a ton of caffeine in it. Kind of brain fvck. Hence today I decided to lower to 750mg and it's much better. But that's what I'm about in this thread. My response to this compound is different than what it supposed to be. So the only sensation regarding Semax for me is a higher energy during the day. Also in the gym I'm a bit like invincible...can workout harder, faster, etc, and feel no fatigue. Do not notice any boost on the focus, better cognitive skills, or memmory etc. Would even say, I'm a bit more distracted recently...in general it's hard for me to say whether I'm happy of Semax or not. On the one hand it is good to be more energetic during the day, and not fatigued after work, when gym is not a chore, but just another easy task of the day. But I wanted to get from it something else. Gonna make it 4 weeks cycle, so it might be changed, but so far I have a mixed feelings.
Following.

Do you mind split testing & journaling lol.
 
Maybe not ADHD, that would be exaggeration. After yesterdays shot of 1mg I was feeling realy high. Like I said, a kind of feeling of very strong pre workout, or high amount of caffeine. It just hit instantly after the shot and last for a couple minutes. The rest of the day I was just feeling like having more energy. Didn't get tired. Whole day couldn't wait to finish work to get to the gym. And when I hit the gym, I was flying. Other than that I forgot to add in the first post I could say my mood is better currently. Feeling more relaxed, less stressed. Also finishing today 20 days cycle of Epitalon, but don't think it may have any impact. Tbh do not feel anything special from Epi. So influance of Semax is noticeable, but in a quite confusing manner on my end.
My experience is basically the same as you describe here, for my second cycle of Semax at least. I am a convert.
I started out on 500mcg subq daily in the morning. Now on 1mg.
Well my first cycle was not as effective. But my second cycle I am using a different vendor and the difference is night and day.
 
My experience is basically the same as you describe here, for my second cycle of Semax at least. I am a convert.
I started out on 500mcg subq daily in the morning. Now on 1mg.
Well my first cycle was not as effective. But my second cycle I am using a different vendor and the difference is night and day.
So what's the difference in particular for you? And btw I find 1mg too high, 750mg is a sweet spot so far.
 
So what's the difference in particular for you? And btw I find 1mg too high, 750mg is a sweet spot so far.
Between the two batches? The first cycle. I kind of felt more awake and alert. But only for brief periods mid morning and aside from that not much at all, if I hadn’t already ordered a kit I wouldn’t have bothered with a second cycle but figured I’d give it another go. Had nothing to lose.
The second cycle with a new batch pretty much exactly as you described it. But not instantly, a bit more of a slow burn. But it kept me going all day. Feeling super productive, tasks I’d been putting off for months are now done. Feeling much less stressed at work (the productivity probably helps). I can focus on tasks.
I was contemplating dropping the dose for the weekend or days when I just want to chill out because today I had got all my housework and tasks done and I wanted to relax but I felt like I just had to keep going haha a little wired.
 
Between the two batches? The first cycle. I kind of felt more awake and alert. But only for brief periods mid morning and aside from that not much at all, if I hadn’t already ordered a kit I wouldn’t have bothered with a second cycle but figured I’d give it another go. Had nothing to lose.
The second cycle with a new batch pretty much exactly as you described it. But not instantly, a bit more of a slow burn. But it kept me going all day. Feeling super productive, tasks I’d been putting off for months are now done. Feeling much less stressed at work (the productivity probably helps). I can focus on tasks.
I was contemplating dropping the dose for the weekend or days when I just want to chill out because today I had got all my housework and tasks done and I wanted to relax but I felt like I just had to keep going haha a little wired.
Gotcha. Yeah sounds very similar to my own experience...but like I said in the first post, not exactly what I was expecting...For all those features I have Mots-c in the freezer, and willing to start next week..
 
Gotcha. Yeah sounds very similar to my own experience...but like I said in the first post, not exactly what I was expecting...For all those features I have Mots-c in the freezer, and willing to start next week..
I’ve tried MOTS-c. I was doing 1mg 3x/week. Didn’t have nearly the same effect. I did feel like it improved my gym sessions but didn’t really help in other aspects like Semax has. Plus the ISRs are annoying. My last injection instantly swelled like a bee sting since decided I’m done with it. That’s just my experience though.
 
Yeah I have. Think will just run this cycle on Semax only, and next time will combine with Selank.
Can you say a little about your thought process on this? Just a whim or are there reasons? I am trying to decide on my cycle.

When you do run them together, do you recon into a single spray, or two?
 

Trending Topics

Forum Statistics

Threads
17,652
Posts
183,187
Members
59,358
Newest
Celia1287
Back
Top Bottom