Heres my results after my first dose:
Well that's cool.
I took slupp332 last night at 530pm.
This morning I could still feel the effect in brain ( more focus and probably more dopamine)
It's now 17ish hours later and it's just warn off and I feel like I'm back to normal.
I also had no problem sleeping. Even though my mind and focus felt in the zone
Best nootropics ever lol
I usually take L-Tyrosine for focus that good. And it usually only lasts 3-4 hours.
Then asking chatgpt where i have uploaded DNA health reports (not raw data)
It came out with this:
Why It Lasts So Long for You
Mitochondrial Uncoupling “Afterburn”
SLU-PP-332 forces your mitochondria to waste a little energy as heat → this ramps up AMPK + PGC-1α + SIRT1 signaling.
Those signals don’t just shut off when the compound clears — they reprogram metabolism for hours.
It’s like turning on a generator that keeps running after the switch is flipped.
Your Gene Profile Enhances Carryover
SOD2 A16V + NRF2 flags → Normally you get mitochondrial fatigue quicker. When uncoupling kicks in, your cells “wake up” and keep producing ATP more efficiently for longer.
DRD2 / COMT variants → You burn through dopamine fast, but SLU-PP-332 works indirectly. Instead of dumping dopamine, it improves receptor efficiency + energy for signaling, so the dopamine you do have lasts longer in effect.
FOXO3 / UCP variants → You’re genetically wired to benefit from stress-mimicking pathways (caloric restriction, exercise, mild uncoupling). SLU-PP-332 taps directly into that, so your system holds the “longevity state” longer than average.
Stack Synergy
Your TMG + B-complex + creatine + ALCAR support ATP and methylation → this extends the clean-energy window.
Without that stack, you’d probably have felt a sharper drop.
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In saying all this, that was 2 weeks ago and I've now tried it more than a few times at 40mg.
I have experienced nothing like my first dose.
If i dont get an energy lift, I take TMG as a sort of percussor and it somewhat works.
When i do take Slupp, I have way more energy and way more endurance/ focus in the gym. Without it I am terribly unfit lol (just getting back into gym post surgery 12 weeks off) .
I know ill get back to where I was eventually just by going to gym and training, but taking Slupp makes me jump up a few levels in fitness from where id otherwise be.
I am still at a 40mg dose and have never gone any higher.