So what is the verdict with reconstituting Cagrilintide then?

[agussie]

Newbie here, recently ordered some reta and cagri from JEEP that should be here by next week.

Now I've done extensive research on reta and I'm comfortable enough in regards to the risks with taking grey market reta.

But I'm very confused in regards to cagrilintide. Between the discussions here and on other forums plus research I've done I initially thought grey market cagri was pretty safe.

I didn't even order any AA and just planned to reconstitute it with normal bac water but all the talk about fibrils and oligomers has me scared a little bit scared if I'm honest so I wanted to have a discussion here.

Alot of the prior discussions are from quite a while ago I imagine with cagrisema likely to hit the market this year we should have a better understanding of how cagrilintide will affect those of us taking grey market.

Look at it this way, if you’re wrong, the Alzheimer’s will make sure you forget about your mistakes.

 

[Bakerskibum87]

I just use BAC. I would be more worried about using not-for-injection AA water than theoretical fibrils.

Same

 

[Lyophilized]

Newbie here, recently ordered some reta and cagri from JEEP that should be here by next week.

Now I've done extensive research on reta and I'm comfortable enough in regards to the risks with taking grey market reta.

But I'm very confused in regards to cagrilintide. Between the discussions here and on other forums plus research I've done I initially thought grey market cagri was pretty safe.

I didn't even order any AA and just planned to reconstitute it with normal bac water but all the talk about fibrils and oligomers has me scared a little bit scared if I'm honest so I wanted to have a discussion here.

Alot of the prior discussions are from quite a while ago I imagine with cagrisema likely to hit the market this year we should have a better understanding of how cagrilintide will affect those of us taking grey market.

Do you know that insulin is also prone to create/form fibrils?
Imagine all the people who have taken insulin all these decades... Do you see them with Alzheimer?
Fibrils that are created in the vial will be "stuck" in your injection site. They are too big to easily migrate, or even if they migrate they don't pass the blood brain barrier.. Too big
The fibrils you have to be afraid of are the ones formed" inside the brain " not on a vial..and the insulin users are proof of this

 

[tncc_rn]

Do you know that insulin is also prone to create/form fibrils?
Imagine all the people who have taken insulin all these decades... Do you see them with Alzheimer?
Fibrils that are created in the vial will be "stuck" in your injection site. They are too big to easily migrate, or even if they migrate they don't pass the blood brain barrier.. Too big
The fibrils you have to be afraid of are the ones formed" inside the brain " not on a vial..and the insulin users are proof of this

Bro, harshing my mellow man! Don't bring logic and biochemical function into this thread.....

 

[Wallydog]

Were did you get cagri and bac?

I know this is a little old but when I was buying through middle man vendor, they sent a 3ml BAC water with the cagri order.

 

[Wallydog]

Bro, harshing my mellow man! Don't bring logic and biochemical function into this thread.....

Moreno Valley? By Lake Elsinore?

 

[Foggy-Hollow]

Fibrils that are created in the vial will be "stuck" in your injection site. They are too big to easily migrate, or even if they migrate they don't pass the blood brain barrier.. Too big

Sooo what happens? "Body has a foreign object" type of programming? Irritation, pus, etc?

 

[Lyophilized]

Sooo what happens? "Body has a foreign object" type of programming? Irritation, pus, etc?

Because English is not my native language, to answer your question I used the search IA. I don't like to use it but it easyer for answering your question

"
Insulin fibrils, which cause firm, palpable subcutaneous lumps known as insulin-derived amyloidoma, occur at common insulin injection sites due to repeated, non-rotated injections. These, often called "insulin balls," typically form in the abdomen, thighs, buttocks, or upper arms

The removal of insulin fibrils—technically known as localized insulin-derived amyloidosis (LIDA) or an "insulin ball"—primarily relies on surgical intervention or strict site rotation. Unlike common lipohypertrophy (soft fatty lumps), amyloidoma fibrils are firm and do not regress quickly on their own"

 

[PAPoots]

I was hoping to find recon tips on this thread.... I'm on 8mg of reta weekly, was 12mg but my sleep was terrible. My sleep is a little better but I've been at 212# for about 3 months and my hunger is outof control. I picked up a 10mg of Cagri to test, but I'm not sure what the easiest way to recon it for starting weekly doses of .125 and .25 mg.

Current history in case it affects dosing or the hope Cagri helps be get in the down slope.
Also on TRT, Tesa, mots-c, nad+ and ipa. The tesa and ipa, most likely are causing my CTS, so I backed of them and the nightly CTS has almost subsided. I thought after the water dropped, I'd are a few pounds drop. Not.

I feel doing with 1ml night be too hard to get the right dose. Even at 3m, it looks odd to me coming out at .75 units on pepcalc.
Hints on the math appreciated

Also, it's bowling night and my thoughts are fuzzy.

 

[Bakerskibum87]

I do 5mg bottle of Cagri with 2 ml BAC and do a 2mg shot every 6 days between Reta pins. 2mg is 80 units so a vial for me is 2.5 pins.

 

[indolent]

I was hoping to find recon tips on this thread.... I'm on 8mg of reta weekly, was 12mg but my sleep was terrible. My sleep is a little better but I've been at 212# for about 3 months and my hunger is outof control. I picked up a 10mg of Cagri to test, but I'm not sure what the easiest way to recon it for starting weekly doses of .125 and .25 mg.

Current history in case it affects dosing or the hope Cagri helps be get in the down slope.
Also on TRT, Tesa, mots-c, nad+ and ipa. The tesa and ipa, most likely are causing my CTS, so I backed of them and the nightly CTS has almost subsided. I thought after the water dropped, I'd are a few pounds drop. Not.

I feel doing with 1ml night be too hard to get the right dose. Even at 3m, it looks odd to me coming out at .75 units on pepcalc.
Hints on the math appreciated

Also, it's bowling night and my thoughts are fuzzy.

Work with the actual mass of your vial, not the nominal one.
Stop trying to do math.
Use the reverse calculator in my signature, not those terrible peptide calculators which might be good for compounded pharma but not for grey.