Some People Lost Too Much Weight With Eli Lilly's Experimental Weight Loss Drug.

Not the worst problem to have haha. But in all seriousness, I can understand being concerned when trying out a new drug and the results being TOO effective. Especially so if they lose muscle mass.
 
One can always stop taking the drug at goal, of course, when one isn’t in the study. I’d like to know if they had any bad effects and why wouldn’t there be a way to keep them in the study without harming them?
Rapid weight loss has been given a bad rep, but studies in the last decade (out of the UK and Australia) showed that rapid weight loss was more beneficial for total weight loss, diabetes, and that it mostly stuck for the three year followup. The assumption is that the person maintains adequate nutritional intake meanwhile.
 
28% in 68 weeks at 12mg doesn't even sound like that much, really -I know many people who are for sure loosing more than that. I'm at 27% in 20 weeks and I wasn't even that fat. (60lb loss) never went above 5mg either.
 
bogardbilla said:
I have a feeling that what really happened was that "Some People Thought They Lost Too Much Weight With Eli Lilly's Experimental Weight Loss Drug"
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That phenomenon is so wild to me. I see it play out on reddit all the time, just random total alarm over "guys I lost too much weight" and they're still really overweight but acting terrified, and maybe ARE terrified and not just internet-performing. I always think "bro, what are you so scared of?" and do not comment because man, that all sounds emotionally messy.
 
sfkid said:
https://share.google/0W874cU62RdlYNJJ3
Interesting that some people dropped out of the trials because they lost too much weight.
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“The answer to the obesity epidemic is not a one-size-fits-all prescription from an online retailer,” said McCoy. “It is a patient and a clinician, working together, choosing the right tool for that specific person at that specific time.”

I actually choked when I read that! My experience has been the EXACT opposite. 25.2% lost in 49 weeks with the online retailer, 4.9% in 30 weeks with a clinician (this last go-round).
 
ambot88 said:
28% in 68 weeks at 12mg doesn't even sound like that much, really -I know many people who are for sure loosing more than that. I'm at 27% in 20 weeks and I wasn't even that fat. (60lb loss) never went above 5mg either.
Click to expand...
It’s an average. Most people’s individual results won’t even be particularly close to that average, you’ll have a bunch of people who lost 40% and a bunch who lost 15% too.
 
This is the wild thing - for most people, even Semaglutide will do the job for most people in terms of weight loss. If you compare the difference between no drug and Sema, Sema and Tirz, and the Tirz and Reta, the gains are now marginal compared to no drug.

We're chasing these kind of incremental improvements where it's not always necessary.

And poor Novo Nordisk, their drugs are effective, but not as effective, and their share price has taken such a hit (good time to buy IMHO!)
 
I understand participants feeling this way… but does the study not require them to find out a healthy weight range for them to stop treatment? I guess the goal is to see whether the medication is working properly or not within the ways they designed it to be, but shouldn’t treatment stop when a participant makes it to an ideal weight range provided by their doctor? I haven’t read much on the study but I would assume that’s how they should be doing it?
 
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