Splitting up a large vial?

[riposte]

Has anyone bought for example a single 100 mg reta vial, and then made their own 10 mg kit out of it? It appears vials and milligram scales are available on Amazon for not much money. Though the “value add” step would seem to make sure you’re maintaining sterility.

 

[soapysnake]

I'm probably extremely naive when it comes to this but I believe it would be pretty difficult to maintain sterility while doing this. Static, moisture and measurement accuracy are all going to be tough as well. You would probably need to spend more money setting up your environment than it costs to just get some high quality gray reta from one of the reputable vendors here... I just got 20 r15 vials for under 200 with shipping

 

[anhydrous]

Yes many people make aliquots but doing so does not involve a scale.

 

[CNCCurrency]

Has anyone bought for example a single 100 mg reta vial, and then made their own 10 mg kit out of it? It appears vials and milligram scales are available on Amazon for not much money. Though the “value add” step would seem to make sure you’re maintaining sterility.

I have not seen anyone offer higher than 60 mg vial? Where did you find 100mg reta?

 

[BNLFL]

I have not seen anyone offer higher than 60 mg vial? Where did you find 100mg reta?

I saw 100's somewhere yesterday looking for Hospira. I can't remember. No way I'd want to mess with splitting that much powder accurately.

 

[GalloB73]

I saw 100's somewhere yesterday looking for Hospira. I can't remember. No way I'd want to mess with splitting that much powder accurately.

You can't split the powder. You can only aliquot a reconstituted vial.

 

[BNLFL]

You can't split the powder. You can only aliquot a reconstituted vial.

I had to look up aliquot.

 

[riposte]

I have not seen anyone offer higher than 60 mg vial? Where did you find 100mg reta?

I can’t discuss sources yet lol. But I think it’s a popular place…

You can't split the powder. You can only aliquot a reconstituted vial.

Why can’t you split powder? My idea is keep the larger sample frozen, pull it out, scoop out a smaller volume and place in a new vial. The parent vial is recapped, evacuated (by syringe) and placed back in the freezer.

While I don’t have access to a glovebox. The idea is open a sterile vial, add powder, bac and recap.

 

[riposte]

I'm probably extremely naive when it comes to this but I believe it would be pretty difficult to maintain sterility while doing this. Static, moisture and measurement accuracy are all going to be tough as well. You would probably need to spend more money setting up your environment than it costs to just get some high quality gray reta from one of the reputable vendors here... I just got 20 r15 vials for under 200 with shipping

You’re probably right, but I’m trying to avoid crypto, so…

 

[CNCCurrency]

I saw 100's somewhere yesterday looking for Hospira. I can't remember. No way I'd want to mess with splitting that much powder accurately.

if you recall please post just for my curiousity

 

[BNLFL]

if you recall please post just for my curiousity

Here you go, no charge. lol

Peptide Test

Peptide Test offers fast, reliable, and accurate peptide testing services and lab supplies. Our tests are performed in Michigan by scientists at our partner lab who are experts in commercial quality control testing of FDA regulated pharmaceuticals.

peptidetest.com

 

[CNCCurrency]

Here you go, no charge. lol

Peptide Test

Peptide Test offers fast, reliable, and accurate peptide testing services and lab supplies. Our tests are performed in Michigan by scientists at our partner lab who are experts in commercial quality control testing of FDA regulated pharmaceuticals.

peptidetest.com

Not the question, he said 100 mg of reta vial not an empty vial? Maybe I'm confused? Thanks anyways

 

[BNLFL]

Not the question, he said 100 mg of reta vial not an empty vial? Maybe I'm confused? Thanks anyways

No, I probably am. I shouldn't read or post without my glasses, and they sit right next to my laptop. I was a 100% wrong, sorry about that.

 

[CNCCurrency]

No, I probably am. I shouldn't read or post without my glasses, and they sit right next to my laptop. I was a 100% wrong, sorry about that.

No worries

 

[CNCCurrency]

I can’t discuss sources yet lol. But I think it’s a popular place…

Why can’t you split powder? My idea is keep the larger sample frozen, pull it out, scoop out a smaller volume and place in a new vial. The parent vial is recapped, evacuated (by syringe) and placed back in the freezer.

While I don’t have access to a glovebox. The idea is open a sterile vial, add powder, bac and recap.

I believe the molecules are attached to the fillers you see in the vial and may not be equally distributed in the powder. So reconstitute then split

 

[Jfrick11]

Has anyone bought for example a single 100 mg reta vial, and then made their own 10 mg kit out of it? It appears vials and milligram scales are available on Amazon for not much money. Though the “value add” step would seem to make sure you’re maintaining sterility.

I would strongly advise against this. There are several major problems with that idea.

First these vials always contain peptide plus excipients/filler, so it's going to be 100mg of Tirz plus an unknown amount of filler. Without validated lab data, you have no way of knowing how much of that powder is actually tirz and how much is filler. So weighing out “10 mg portions” doesn’t mean you’re getting 10 mg of tirzepatide. You’d just be weighing 10 mg of mixed powder.

Second, consumer milligram scales are not reliable enough for that level of precision. Static, humidity, airflow, and transfer loss all affect powder measurements. You could easily end up with inconsistent amounts.

Third, and most importantly, sterility. Redistributing peptide powder into new vials requires sterile pharmaceutical handling. Labs do this in controlled environments with laminar flow hoods and validated sterile technique. Doing this at home introduces contamination risk you can’t see.

So you’d be dealing with three major unknowns:
You don’t know the true peptide content
You can’t reliably portion it accurately
You can’t realistically maintain sterility

If you’re even considering this, it would be wise to spend more time reading about peptide formulation, excipients, and sterile handling first. Injectables are not a place to learn through a bright idea or trial and error.

 

[riposte]

I would strongly advise against this. There are several major problems with that idea.

First these vials always contain peptide plus excipients/filler, so it's going to be 100mg of Tirz us an unknown ant of filler. Without validated lab data, you have no way of knowing how much of that powder is actually tirz and how much is filler. So weighing out “10 mg portions” doesn’t mean you’re getting 10 mg of tirzepatide. You’d just be weighing 10 mg of mixed powder.

Second, consumer milligram scales are not reliable enough for that level of precision. Static, humidity, airflow, and transfer loss all affect powder measurements. You could easily end up with inconsistent amounts.

Third, and most importantly, sterility. Redistributing peptide powder into new vials requires sterile pharmaceutical handling. Labs do this in controlled environments with laminar flow hoods and validated sterile technique. Doing this at home introduces contamination risk you can’t see.

So you’d be dealing with three major unknowns:
You don’t know the true peptide content
You can’t reliably portion it accurately
You can’t realistically maintain sterility

If you’re even considering this, it would be wise to spend more time reading about peptide formulation, excipients, and sterile handling first. Injectables are not a place to learn through a bright idea or trial and error.

I was leaning against at it, but this basically seals it as not being remotely worth it. looks like I should look into crypto…

 

[woundcarping]

The amount you don’t know of what you don’t know should be enough to dissuade you from continuing this line of thought.

 

[dirtyharry]

You’re probably right, but I’m trying to avoid crypto, so…

If you just dont wanna buy crypto for personal reasons then I get it. If not though, I'd be happy to help however I can. Buying Bitcoin is insanely easy now-a-days. Coinbase is a super noob-friendly place to do so.

 

[riposte]

If you just dont wanna buy crypto for personal reasons then I get it. If not though, I'd be happy to help however I can. Buying Bitcoin is insanely easy now-a-days. Coinbase is a super noob-friendly place to do so.

I appreciate the offer, but I should just buck up and figure it out. I have a brother who basically speculates in this stuff full-time so I can ask him.

 

[lessthanhalf]

There is also no way to know that the peptide is evenly mixed with the filler, and there is no reason at all that any trouble would have been gone to to ensure this. As it is designed to be dissolved. I do not know if the drug is mixed with filler and then measured to put in the vials or if the drug is added and then filler added to each vial, in the second case it would be distributed very unevenly. And you could end up with one vial having most of the drug in it if you divide the powder in 10 , scales accurate to less than 5mg are not cheap as well.
Also sterility is impossible to maintain if dealing with the powder.
Trying to do it with powder has higher risks of dose inaccuracy and contamination.
There are no real disadvantages of dissolving the contents in bac, as much as fits in the vial ?3ml, dividing it by 10 -0.3ml in each new sterile vial. then dilute that to what concentration you want to use.
Generally freezing reconstituted peptides is not ideal due to peptide degradation , but in this case if you are on very low doses, one or a few percent degradation is of no consequence from a single freeze thaw cycle. And is a much better option than leaving them in the fridge for many months due to the risk of degradation and bacterial or fungal growth.
So reconstitute , dilute into multiple vials, dosing accuracy is maintained, use one freeze the rest.
or buy smaller dosage vials, the difference in cost is not huge and a lot less stuffing around.

 

[skeptick]

Has anyone bought for example a single 100 mg reta vial, and then made their own 10 mg kit out of it? It appears vials and milligram scales are available on Amazon for not much money. Though the “value add” step would seem to make sure you’re maintaining sterility.

gotta agree with those who are saying to scrap the dividing of powder idea but the adding of a known amount of BAC is doable provided good sterile methods are used. Congratulations on thinking like a "MAD SCIENTIST". Gets most everybody...

 

[WLBLD]

Not sure if it would still be good, but cant you recon w/ bac water, split into pen cartridges or vials & freeze the ones not using yet?

 

[soapysnake]

I appreciate the offer, but I should just buck up and figure it out. I have a brother who basically speculates in this stuff full-time so I can ask him.

Was in the same boat and just did my first crypto transaction. Bought SOL on Kraken pro, sent to Exodus wallet, converted to USDT and then sent to Vendor and it wasn't bad at all.