SRY

I wonder how many people complaiing about this stuff have cats in their house and are fine with the fact they now have toxoplasmosis, but are freaking out about little specks in their Tirz like it’s the end of the world. I will pay $1 for your contaminated vials!
 
To my knowledge, we don't know for sure what the SRY and Nexa particles were in the first place, except with the Nexa cardboard issue. They are certainly another reason to filter, which most do not. And I would hate to wait group-buy waiting times to get something from SRY, only to have a lackluster-looking product.

But yes, it would probably be fine, at least after being filtered (to filter out the material itself as well as the more likely presence of bacteria).

SRY is also the same vendor who shipped reta as tirz. So there are bigger concerns as well (with any vendor since SRY learned the hard way):

Personally, I wouldn’t suggest to buy from that company. One of the kits was labeled Tirzepatide and it was Retatrutide. I take 15mg Tirzepatide a week, imagine what 15mg of Reta would do to me!
Probably give me a heart attack or stroke!
Very dangerous miss labeling of the viles.
 
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SRY seems to be really dropping the ball in many ways.

  • Every rep has different rules for payment/ordering/stock.
  • Incredibly long ship times of upwards of 6+ weeks with freight being stopped, rerouted from Fedex, switched to USPS.
  • Surprise tariff/customs fees after the fact (like I ain't paying that - get bent).
  • Crazy underfills (at least they are admitting it and discounting pricing ) or crazy overfills (not saying so you and you might get a whollop of a shot- recently tested semax vial was like 10mg over).
For me, after six orders (the last one being a pain), I am ready to branch out and try some new places. I am placing orders with QYC and WBS this week for a few things. Gonna need to spread my wings.
This order with Lucy was going great until it got to the US. I cant pay the duty fees because they used a phone number with DHL that is not mine and you need to get a one time passcode. Lucy said she would look into it but its been 4 days and she's not responding to me trying to get an update. So now the order is just stuck in some wearhouse. I am guessing its just a loss at this point. Just frustrating though. However I did make an order with LISA from the US warehouse a few days after my order with Lucy and it went just fine. 🤷‍♂️
 
SRY's US Warehouse was very attractive to me because I was doing one-kit orders and didn't want to pay for shipping.
 
This order with Lucy was going great until it got to the US. I cant pay the duty fees because they used a phone number with DHL that is not mine and you need to get a one time passcode. Lucy said she would look into it but its been 4 days and she's not responding to me trying to get an update. So now the order is just stuck in some wearhouse. I am guessing its just a loss at this point. Just frustrating though. However I did make an order with LISA from the US warehouse a few days after my order with Lucy and it went just fine. 🤷‍♂️
Out of an act of desperation and no comms from Lucy. I called the courier directly and told them I had a package that needed duty fees to be paid but the vendor provided the incorrect phone number to get passcode. After some back and forth they let me make the payment eventually. Crisus averted but I would be reluctant to try again. Definitely not with Lucy though. Nice person though just absent in communication when needed.i hope this helps others.
 
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I just learned SSA also offers free shipping for single kits from their US Warehouse. I confirmed just now with one of their reps.
 
I just learned SSA also offers free shipping for single kits from their US Warehouse. I confirmed just now with one of their reps.
Not according to their post here in the Vendor Connection 39 minutes ago...MOQ 2 kits.

I totally believe you were told that though...

 
Thanks. Another rep on their Discord just said they won't ship only one kit from their US warehouse, even if you offer to pay for shipping. At least now I know which rep understands English better (Tansy, not Ada).
 
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I just got my first order from SRY. Two T40 kits, green caps.
Fast shipping from the US warehouse.
After examination of one kit, I noticed black specks at the shoulder of 3 of the vials. I am not sure if it's a vial problem or a peptide quality problem. I am contacting SRY to discuss further. And I will be examining my other kit today.
Many people have had problems with " bugs" in there vials from SRY lately.
These T40s tested great by 2 sources. ( not me) but in the testing groups , no mention of black spots/imperfections. View attachment 6443
Thanks again for this picture you posted in April.

According to Google Gemini, black specks are most likely to due environmental contaminants rather than due rubber stoppers of a different color:

Given that the rubber cap is gray, here's a revised assessment of the likely culprits for black specks, focusing on "during manufacturing":

  1. Environmental Contaminants (Highly Likely):
    • Dust/Dirt: This becomes a very strong candidate. Dust particles can be black or dark gray, especially in an industrial environment.
    • Fibers: Dark fibers from clothing (even cleanroom garments, if a dark underlayer is worn), wipes, or other materials can be present in the air and settle into open vials during filling.
    • How it happens: During the period the vials are open for filling, airborne particulates can easily enter.
    • Appearance: Varies. Dust can be irregular, fibers might be elongated.
  2. Manufacturing Equipment Residue (Highly Likely):
    • Metallic Abrasion: As previously mentioned, wear and tear on metal parts of the filling machinery (e.g., augers, nozzles, conveyors) can generate tiny dark metallic flakes.
    • Carbonized Residue/Lubricants: Burnt-on organic material, carbon deposits from heating elements, or dark lubricants/greases used on machinery can flake off.
    • How it happens: Direct contact or close proximity of the equipment to the open vial or product stream.
    • Appearance: Metallic might be shiny, carbonized could be flaky, lubricants might appear smudged.
  3. Contamination from the Gray Stopper (Still Possible, but with caveats):
    • While the bulk of the stopper is gray, it's possible that:
      • Surface Discoloration: The surface of the stopper, particularly if it's been exposed to heat or certain chemicals during processing, might have developed localized dark spots that then flake off.
      • Inclusions: Very rarely, manufacturing defects in the rubber itself could lead to dark inclusions that become exposed and detach.
      • Carbon Black: Many rubber formulations use carbon black as a filler to enhance properties. While the overall stopper might appear gray due to other components, it's conceivable that in very tiny, pure fragments, the carbon black could make them appear darker. This is less common if the stopper appears uniformly gray.
  4. Raw Material Contamination (Less likely for just black specks, but possible):
    • If the original white powder itself contained black impurities, these would be present throughout the batch. Quality control on raw materials should ideally catch this.
  5. Insects/Pest Contamination (Low, but still a concern for GMP failure):
    • As discussed, in a compromised cleanroom environment, tiny insect fragments could appear as black specks. This would be a significant quality control breach.
In summary, if the stopper is gray:
  • Environmental dust/fibers and manufacturing equipment residue (metallic or carbonized) become the most probable causes for black specks during the manufacturing process.
  • The rubber stopper itself becomes a less likely direct source of black specks, unless there's a specific discoloration or inclusion issue.
Regardless of the source, any foreign particulate matter in a pharmaceutical product is unacceptable and requires immediate investigation and corrective action to prevent recurrence.

At legit facilities, rubber stopper particulates are the most likely cause if the stoppers were the same color:

1. Rubber Stopper Particulates (Highly Likely during manufacturing):

  • How it happens: During the filling and stoppering process, rubber stoppers are mechanically inserted into the vials. This mechanical action can cause tiny fragments of the stopper material to shed, especially if the stoppers are not perfectly clean, if the machinery is not optimally aligned, or if the rubber is of a lower quality. These fragments would fall directly into the vial with the powder.
  • Appearance: Typically small, irregular, and black or dark gray. This remains a very strong candidate.
2. Environmental Contaminants (Possible during manufacturing):

  • Dust/Dirt: Even in controlled environments (like cleanrooms), airborne particulates can exist. If air filtration systems aren't perfectly efficient, or if there's a momentary breach in containment, dust or dirt particles can settle into open vials during the filling process.
  • Fibers: Clothing fibers from operators (even in cleanroom suits), wiping cloths, or packaging materials can become airborne and settle into vials.
  • How it happens: Vials are typically open for a period during the filling process before the stopper is applied. This is the window of opportunity for airborne contaminants to enter.
  • Appearance: Varies widely depending on the contaminant. Fibers might be elongated, dust can be irregular.
3. Manufacturing Equipment Residue (Possible during manufacturing):

  • Metallic Abrasion: If the filling machinery (e.g., augers for powder, nozzles) experiences wear, tiny metallic particles can abrade off. These could be dark and appear as specks.
  • Carbon/Grease/Oil: Lubricants used on machinery, or carbonized residues from heating elements or motors, could potentially flake off and enter the product. These would often be black or dark brown.
  • How it happens: Directly from the equipment coming into contact with or in close proximity to the open vial or the product stream.
  • Appearance: Metallic particles might be shiny or crystalline. Grease/oil could be irregular or smudged.
4. Raw Material Contamination (Less likely for just black specks, but possible):

  • If the raw white powder itself was contaminated before it entered the manufacturing process, those contaminants would be present. However, raw materials usually undergo quality checks to prevent this. If the specks are only found after processing, it points to a contamination during the manufacturing steps.
5. Insects/Pest Contamination (Low, but not Zero, if GMP is compromised during manufacturing):

  • How it happens: In a properly controlled pharmaceutical manufacturing environment (which operates under strict Good Manufacturing Practices - GMP), the risk of insects entering open vials is extremely low. Facilities have rigorous pest control programs, sealed environments, airlocks, positive pressure, and air filtration.
  • However, if GMP is compromised:
    • Breaches in Containment: If a cleanroom door is left open, or if there are cracks/gaps in walls, insects could potentially enter the facility.
    • Poor Housekeeping/Sanitation: Accumulation of waste, standing water, or uncleaned areas can attract pests.
    • Unscreened Intakes: If air intake vents are not properly screened, insects could enter.
    • Contaminated Raw Materials (Less common for visible insects): Rarely, bulk raw materials might have insect fragments, but typically these would be filtered or identified before reaching the final filling stage.
  • Appearance: This is where it gets trickier. A whole fly would be obvious. But tiny insect fragments (legs, antennae, chitinous bits) could appear as small black specks. These would often be irregular in shape and might have specific morphological features if viewed under magnification.
Summary for "During Manufacturing":

  • Most Probable: Rubber stopper particulates are still the front-runner.
  • Very Possible: Environmental dust/fibers and manufacturing equipment residue.
  • Possible (but indicates a serious GMP failure): Insect fragments. For visible "specks" in a vial, it's more likely to be inert debris than a whole insect unless the specks are larger and clearly identifiable as biological.
Ultimately, identifying the precise nature of the black specks would require laboratory analysis (e.g., microscopy, spectroscopy) of the specks themselves. This is a standard procedure in quality control for pharmaceutical products whenever foreign matter is detected.
 
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To my knowledge, we don't know for sure what the SRY and Nexa particles were in the first place, except with the Nexa cardboard issue. They are certainly another reason to filter, which most do not. And I would hate to wait group-buy waiting times to get something from SRY, only to have a lackluster-looking product.

But yes, it would probably be fine, at least after being filtered (to filter out the material itself as well as the more likely presence of bacteria).

SRY is also the same vendor who shipped reta as tirz. So there are bigger concerns as well (with any vendor since SRY learned the hard way):
The reta-tirz mix up is what I circle back around to whenever I start eyeing them. No thanks.
 

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