Stalled

[brooke0620]

Hey guys,

So I started S in October. I have lost 45 lbs. I was on the max dose and have been stalled for a month. I switched to T at 2.5 mg. That did nothing and food noise is back. I did 2.5 more midweek and started Saturday on 5. Still talked, still hungry, still having craving and food noise. I have tried every trick. More water, more calories/less calories , changing injection sites. I’m losing hope. Please help!!

 

[jaestar]

From what I have read, Semaglutide has a lot more food noise reduction than tirzepatide. How long was your stall? I know some people add a small dose of sema if the food noise suppression wears off on tirz or reta.

 

[FrankTdog]

Going from the max dose of Sema to the minimum dose of tirz could be a factor as well. It may not hurt to go ahead and bump up to 5 and see how that treats you.

 

[Skidude]

Most of the posts I have seen when changing from one GLP-1 to another, they continue current dosing, slightly decreasing, while titrating up on new GLP-1
This might also benefit you.
Those that use Tirz also sometimes add a sprinkle of sema

 

[Calm Logic]

There is also possibly more variability with how one's body responds after losing a lot of weight already.

 

[Iamnew2this]

Hey guys,

So I started S in October. I have lost 45 lbs. I was on the max dose and have been stalled for a month. I switched to T at 2.5 mg. That did nothing and food noise is back. I did 2.5 more midweek and started Saturday on 5. Still talked, still hungry, still having craving and food noise. I have tried every trick. More water, more calories/less calories , changing injection sites. I’m losing hope. Please help!!

If you were on the max dose of sema, it might be probable to increase your dose of tirz again. 5mg isn't a therapeutic dose. You might have to go to 7.5mg or even 10mg. You should be feeling it by then. It wouldn't hurt to try as long as, you don't have many bad side effects at 5mg.

 

[Calm Logic]

I remember someone saying somewhere (in other words, don't quote me), that 7.5mg of tirz is like the max dose of sema. I don't know if that's true, but it may be true for someone.

Like everyone else, I agree with upping the tirz (or whatever else you want to up). I have only been on tirz, and I went up 2.5 mg each week until I reached 10 mg.

When you were stalling with the sema, how did the food noise/cravings compare to now? In other words, are you eating more now (or wishing you were) than when you were stalling on the sema? Or are the stalls similar, including with the scale (or blood sugar or whatever)?

Something I plan to do if/when I stall for weeks is to try continuous glucose monitoring, which has always seemed interesting to me anyway (despite costing $90 a month or so). Other options include adding a non-GLP medication like phentermine or metformin. Another way to manage a stall (mostly from the world of "bro science" but it applies to women too) is to focus on gaining muscle (focusing on body composition rather than weight).

 

[Skidude]

It is also my understanding, not verified, that Tirz has less blocking of food noise but has more feelings of satiety.
It has been my experience when I absolutely kill my goal of 1200 calories, and feel like I am cheating like an animal at a feast, my calories remain between 1800-2000, but I am full.
Also, anecdotally, when I have gained a few pounds, it has not been when I over ate, and I am baffled as to why-

 

[Calm Logic]

A study equating 5 mg of tirz to the efficacy of 2 mg sema:

"HbA1c and weight reductions were significantly greater for tirzepatide 10 and 15 mg versus semaglutide 2 mg and were similar for tirzepatide 5 mg versus semaglutide 2 mg."