For me, and I think for most researchers, Retatrutide provides noticeably better appetite suppression than Tirzepatide does. Reta is not near the level of Semaglutide or Cagrilintide in this respect but is significantly better than Tirz.
Reta is NOT Adderall. There is no Reta 'boost' so-called but it does not create any fatigue. On Tirz I was accustomed to an afternoon nod or nap every day. With Reta I don't need it. You should note that I am 72 years old and a nap would seem a likely feature of every day
Just as Sema does Tirzepatide has side effects. They are typically 'half' or less than that of Sema but Tirz DOES have them. Being dose dependent they increased at the higher dosages I required.
Retatrutide has sides as well but roughly half as much as Tirz - very few actually.
Food noise is minimal with either peptide but it has soon required 10-12mg weekly to keep it low. Reta is very pleasant - dosed correctly I experience no actual hunger UNLESS my wife starts roasting peppers or sweating onions and I can smell it. Even then it is something of an intellectual exercise - "Am I hungry? I guess I could be but nah, not right now I'd rather do (whatever)."
It isn't anhedonia. Put a well-prepared meal in front of me and I will certainly enjoy every bite I take. It won't be too many bites however
I hope this communicates something useful to you Smokey. I feel I waffle too much with these subjective feelings.
Dennis