Stopping GLP-1 Drugs Triggers Weight Regain 4x Faster Than Ending Exercise

[ThatNextGril]

Yes my eating habits changed. The food off switch was broken again. Exercise habits stayed the same: Swimming more than 6 miles per week and hiking 1000 foot ascent hikes 1 or 2 x per week. Sprinkle in a little cycling and weight training. You are correct the caloric intake drastically increased.

This would be me if I were to stop taking them. I've come to accept that for me, I can handle being hungry as well as not necessarily feeling "full" during or right after a meal, and I've always been active enough and love the gym. It's completely about the food noise itself. Even now, I will get legit hungry, and know I need to eat, but it's been so absolutely freeing not needing to give into it immediately. I can finish whatever task I'm on, and sometimes even get distracted by another, and then remember I need to eat. The decades of my life of thinking about food taking the top spot in my brain every day are behind me - and I'm kinda pissed that these drugs and grey market purchases weren't available then! - and I will not go back to that misery. I use tirz because it was better than sema for the food noise, but if by the time I'm in maintenance or even just down the road there is an API that just targets food noise, I'll probably take that. But, then again, tirz is tirzing and I've got 4 years of it in my freezer so maybe it'll just be that to the end.

 

[swimmer]

What is so bad about taking something the rest of your life that reduces heart attacks, strokes, risk of dementia etc. People take vitamins and supplements with the hope of a fraction of the benefit of a glp1.

 

[jw717us]

What is so bad about taking something the rest of your life that reduces heart attacks, strokes, risk of dementia etc. People take vitamins and supplements with the hope of a fraction of the benefit of a glp1.

Not to mention the concept of food noise. My spouse has had her eye’s opened to what she describes as “How normal people relate to food”. She always struggled with the background noise and, while successful, it was an ongoing struggle. Add the reduction of THAT mental load to all of the potential benefits? For someone like her I can’t see a reason in the world to not continue at a minimum dose!

 

[Foggy-Hollow]

What’s more, few studies were at low risk of bias.

This is very important. Bias in = Biased conclusion out.


Also important: HOW did patients discontinue? Every FDA study I've read jerks the dosage from therapeutic to zero. (Remember, therapeutic doesn't mean max dosage.)

If someone took an SSRI and a doc took them from therapeutic dose to zero, the world would see the doc's malpractice.

Maybe, just MAYBE, some people can discontinue, and some cannot, just like SSRIs. It's not a new concept.

Companies have a vested interest in telling the weight gain story. Why would they even attempt to taper off patients?

We need to be cautious of bias in data. At least this one admits to it.

Edit:
For the record, we need to advocate for ourselves, and if that means you need the med, then please take care of yourself!

My beef is the bias data producing headlines.