On 2.5 and 5 mg I had good results with with weight loss and blood sugar but had a lot of diarrhea. Sometimes going 10 times in a row. Then a few days of constipation. By the time I started at 7.5 mg it tapered off. I had to skip a week for a procedure and the said it was ok to take 7.5 mg again the next week. I got very sick with nonstop diarrhea and threw up a few times. Ended up going to the ER and got an IV of magnesium. The next week I tried 5 mg and same thing happened (not as much diarrhea and didn’t go to ER) but nausea and throwing up. I stopped taking it for 6 weeks now and my appetite is back. If I start up on 2.5 mg again what can I do different? I usually to it in my stomach on Friday mornings. Should I try a different injection. Take a different time? My friend changed hers to nighttime and it seemed to help.