Switching from BAC water to BAC Saline (with reasoning and general impressions)

Camlbacker

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As anyone who has been conducting research in this space in the last several months knows, the Gold Standard Hospira Bac Water has gone up substantially in price and become harder to get. When Amazon pulled all the BAC off their site and demand for Hospira made it pretty scarce for a few weeks and ultimately more costly, I decided to start researching alternatives. Like most people living in 2026, I don't particularly appreciate being price gouged; beyond that there were a few weeks there where people weren't sure where to get a good supply of BAC water to continue their research. This would not do for me. I had gotten a few bottles of Lambda just to see if there was any practical difference between it and the Hospira. For me, there isn't one that I can discern so far into my third bottle, other than that Lambda uses glass vials (quite preferable in my view) and that the bottles are tall and narrow and easy to knock over, which obviously isn't ideal. So once they got their crap together with their credit card processing, I ordered a bunch more Lambda, just in case the BAC water shit really hit the fan.

Like a lot of you, I find some peps to be spicy. For me, Mots-C is the worst of the worst in this regard; but also for me it's some of the most valuable research I do on an ongoing basis, so it behooves me to find a way to minimize ISRs. Higher dilution ratios do improve things, however even a 10mg/ml dilution using 4ml for a 40mg vial doesn't remove ISRs entirely with regular BAC. I could go up to 8, but under the current circumstances I would prefer to conserve BAC. I've been hearing a lot about BAC Saline in recent weeks and how and why it seems to improve ISRs, and it's definitely cheaper: I just bought some for less than $7 a bottle, and you can get a case of 24 for around $100.

Today began my research using BAC Saline for reconstituting Mots-C and Korean Glutathione (the pink Glutaone for the initiated). I reconned the Mots at 2ml per 40mg. It reconned crystal clear and dissolved completely in a couple of minutes. For the Gluta, I started with 3ml for a 1200mg vial; when that took awhile to dissolve, I added 1ml and that took care of the issue. Dissolved crystal clear. I don't have much if any issue with Gluta straight into the ventral glute, and if anything, it's even cleaner using BAC Saline. 1st dose was .5ml for a total of 150mg. Uneventful. The Mots-C is a bit more nuanced. The ISR is pretty minor so far (less than it would be with regular BAC, I think), and I will have a better sense of that tomorrow morning and over the next few days as I continue my work. I will recon the next vial with 4ml to see if that further reduces the ISR or eliminates it entirely.

If there is an interest in the community for this particular subject matter, I will be glad to update with any new and relevant information. If you have any questions about anything, feel free to ask. My understanding is that Reta and Tesa/Ipa are not compatible with BAC Saline, so at least for now, I'm not going to try those. I will be attempting with SS-31, Klow and its individual components, NAD, and probably a couple of others once I have adequate stock to sacrifice a vial to the research gods if it comes to that. As always, please keep the discourse non-violent, and thanks so much for reading.
 
You know, I'd love to see more robust discussions on this. My mom does klow, epitalon, and tirz. She'll never use reta because she'll never need it. She's got five bottles of bac water and that'll last her at least a year, but the price just keeps going up and up. I have two cases, and she'll never run out on my watch, but I was thinking about how I don't actually know if those three (six of you count the individual components of klow) would be just fine to use with saline.
 
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YES! Thanks for this detailed info! I got myself into a righteous tizzy earlier today related to reconstitution, pH and spicy shots, so this is exactly the kind of info I’m looking for (plus I have some NaCl BAC on order for the NAD+/SS-31/MOTS-C protocol). Watching this thread.
 
As anyone who has been conducting research in this space in the last several months knows, the Gold Standard Hospira Bac Water has gone up substantially in price and become harder to get. When Amazon pulled all the BAC off their site and demand for Hospira made it pretty scarce for a few weeks and ultimately more costly, I decided to start researching alternatives. Like most people living in 2026, I don't particularly appreciate being price gouged; beyond that there were a few weeks there where people weren't sure where to get a good supply of BAC water to continue their research. This would not do for me. I had gotten a few bottles of Lambda just to see if there was any practical difference between it and the Hospira. For me, there isn't one that I can discern so far into my third bottle, other than that Lambda uses glass vials (quite preferable in my view) and that the bottles are tall and narrow and easy to knock over, which obviously isn't ideal. So once they got their crap together with their credit card processing, I ordered a bunch more Lambda, just in case the BAC water shit really hit the fan.

Like a lot of you, I find some peps to be spicy. For me, Mots-C is the worst of the worst in this regard; but also for me it's some of the most valuable research I do on an ongoing basis, so it behooves me to find a way to minimize ISRs. Higher dilution ratios do improve things, however even a 10mg/ml dilution using 4ml for a 40mg vial doesn't remove ISRs entirely with regular BAC. I could go up to 8, but under the current circumstances I would prefer to conserve BAC. I've been hearing a lot about BAC Saline in recent weeks and how and why it seems to improve ISRs, and it's definitely cheaper: I just bought some for less than $7 a bottle, and you can get a case of 24 for around $100.

Today began my research using BAC Saline for reconstituting Mots-C and Korean Glutathione (the pink Glutaone for the initiated). I reconned the Mots at 2ml per 40mg. It reconned crystal clear and dissolved completely in a couple of minutes. For the Gluta, I started with 3ml for a 1200mg vial; when that took awhile to dissolve, I added 1ml and that took care of the issue. Dissolved crystal clear. I don't have much if any issue with Gluta straight into the ventral glute, and if anything, it's even cleaner using BAC Saline. 1st dose was .5ml for a total of 150mg. Uneventful. The Mots-C is a bit more nuanced. The ISR is pretty minor so far (less than it would be with regular BAC, I think), and I will have a better sense of that tomorrow morning and over the next few days as I continue my work. I will recon the next vial with 4ml to see if that further reduces the ISR or eliminates it entirely.

If there is an interest in the community for this particular subject matter, I will be glad to update with any new and relevant information. If you have any questions about anything, feel free to ask. My understanding is that Reta and Tesa/Ipa are not compatible with BAC Saline, so at least for now, I'm not going to try those. I will be attempting with SS-31, Klow and its individual components, NAD, and probably a couple of others once I have adequate stock to sacrifice a vial to the research gods if it comes to that. As always, please keep the discourse non-violent, and thanks so much for reading.
Please do! Very interesting assessment.
 
Yes!! I’ve got bac saline to try with mots-c because I’m scared, lol…Klow gave me ISR for 84 hours!! Please update with your progress.
 
@randompersonrandom In my meanderings through TG I came across this PDF that seems to contradict some of the other stuff I've read here and on TG about which peps are compatible with BAC Saline and which aren't. I've read that Tirz is fine, but Reta is not. According to this, all GLPs and Cagri/Elora are the highest risk of any peptides, and that Epitalon, which I also intend to use regularly going forward is in the lowest risk category. All of the components of Klow are in the lower risk categories, but it doesn't address Klow itself and whether the blend might be more inherently unstable than the individual peps (the age-old pep debate rages back into the fore whether we like it or not) and thus problematic for your mom. I do intend to try BAC Saline with Klow at some point in the future once I procure a more substantial supply unless, as with Reta and Tesa, I have strong evidence to believe that it won't work. Like you, I have enough BAC to last me awhile if this experiment turns out to be star-crossed. If I can use BAC Saline for Mots-C and SS-31 that would be a win for me; anything else would be a bonus.

Bacteriostatic Saline vs "Naked" Lypholized Pucks

For my part, I definitely want to keep ISRs and costs to a minimum and keep control of my supply for the items I use regularly. Those are my main considerations here. This doesn't have any citations, so for all I know this person pulled this chart out of their armpit and dressed it up with some chemistry mumbo jumbo that is above my pay grade. Anyone with more knowledge in this area can feel free to weigh in on it.

@Alc23 Regarding ISR with Klow: I had a lot of issues with this as well when I first started using it, including ISRs that lasted several days. I've eliminated any injection site reactions with Klow and would suggest the following, in order of importance (in my sense of it anyway, your mileage may vary a bit): 1) Inject at a 90 degree angle into the ventral glute (side-butt). It doesn't seem like needle length matters for me, but I also don't use anything shorter than 8mm. I also don't use anything long enough that it would technically be considered intramuscular. I have noticed that with Klow, deeper is better, thus the 90 degree angle recommendation. (With Mots-C, FYI, I studiously avoid risk of anaphlaxis by using the shortest needle and keeping the injection as close to the skin surface as possible.) 2) Use a lot of BAC Water ie: 5ml for a vial of Klow 80 3) Let the mixture warm up close to room temperature before you inject and 4) Adding extra KPV if need be. Klow is one of the best tools in this space for the people who need it, so I hate to see people not use it because of ISRs. I feel the same way about Mots-C, just the injection technique I use is different as I discussed above.
 

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