Swollen legs on reta?

sunnygirl

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I’ve noticed that my feet have been slightly more swollen since I started taking retatrutide, 0.5 mg. Nothing too concerning, but socks that never used to leave marks around my ankles now do deeper than before.

I’ve tried looking for information about leg swelling while taking GLP-1 medications, but everything seems pretty contradictory. Some sources say it’s not a normal side effect, while others say it can happen.

Has anyone else experienced swelling or is currently dealing with swollen feet or legs while taking retatrutide?
 
I’ve noticed that my feet have been slightly more swollen since I started taking retatrutide, 0.5 mg. Nothing too concerning, but socks that never used to leave marks around my ankles now do deeper than before.

I’ve tried looking for information about leg swelling while taking GLP-1 medications, but everything seems pretty contradictory. Some sources say it’s not a normal side effect, while others say it can happen.

Has anyone else experienced swelling or is currently dealing with swollen feet or legs while taking retatrutide?
Interesting, everyone in my group taking it has had their inflammation go down.
 
Are you less active with the caloric deficit? Moving around more should keep the lymph moving.
 
Yes! I just noticed the other day I had some swelling in my legs for the first time. Im a pretty active person and on my feet for 10-12 hours per day. I cant quite pin it on the reta yet. Going to try a couple different things to see if I can figure out what's causing it.
 
Yes! I just noticed the other day I had some swelling in my legs for the first time. Im a pretty active person and on my feet for 10-12 hours per day. I cant quite pin it on the reta yet. Going to try a couple different things to see if I can figure out what's causing it.
Please let us know!
 
Are you less active with the caloric deficit? Moving around more should keep the lymph moving
Im keeping the same routine before staring reta. Ill try to add more walks to see if helps
 
I’ve noticed that my feet have been slightly more swollen since I started taking retatrutide, 0.5 mg. Nothing too concerning, but socks that never used to leave marks around my ankles now do deeper than before.

I’ve tried looking for information about leg swelling while taking GLP-1 medications, but everything seems pretty contradictory. Some sources say it’s not a normal side effect, while others say it can happen.

Has anyone else experienced swelling or is currently dealing with swollen feet or legs while taking retatrutide?
Swollen feet/ankles is not a known side effect and the dose is very low to be doing much at all. I would wonder if it is unrelated. Depending on age and overall health it might be worth a medical opinion. It is more common in women, and with varicose veins, and with age , and with prolonged standing at work, but there are less harmless causes as well.
 
No swelling here. Swelling is blood pooling in tissue around ankles, not pulled up by the hearth. Google the possible causes. Need to drink more water on GLP1. Blood thicker than usual? Get medical checkup. The conditions I got in past two years (dry eyes, NAION, kidney stones, etc) could be related to getting older. Unable to prove any was glp1. Read up on ABI test to check Ankle Brachial Index, to measure blood pressure difference between your ankles and your arms.
 
No swelling here. Swelling is blood pooling in tissue around ankles, not pulled up by the hearth. Google the possible causes. Need to drink more water on GLP1. Blood thicker than usual? Get medical checkup. The conditions I got in past two years (dry eyes, NAION, kidney stones, etc) could be related to getting older. Unable to prove any was glp1. Read up on ABI test to check Ankle Brachial Index, to measure blood pressure difference between your ankles and your arms.
What's that now? Hearth is around my fireplace.
 
Makes me wonder whether it's even reta. 🤔 Sounds like edema, although that’s usually a side effect of GH secretagogues. Only recently, I’ve seen vials turning out during the testing to be mislabeled.
 
I’ve noticed that my feet have been slightly more swollen since I started taking retatrutide, 0.5 mg. Nothing too concerning, but socks that never used to leave marks around my ankles now do deeper than before.

I’ve tried looking for information about leg swelling while taking GLP-1 medications, but everything seems pretty contradictory. Some sources say it’s not a normal side effect, while others say it can happen.

Has anyone else experienced swelling or is currently dealing with swollen feet or legs while taking retatrutide?
are you eating and moving enough? when i had an ed my legs got really swollen from malnutrition + not getting enough movement due to low energy.
 
Care to tell the story of the NAION? You’re the first, first hand experience I’ve seen.
re NAION: after one year on Tirz, down 60#, I suddenly lost vision in left eye: bottom half went blank, like a curtain pulled up, for about 4-5 minutes. I was outside, soldering a few wires. Nothing extraneous. Eye doctor called it NAION, and told me to stop Tirz (I did not). According to her, this was a known side effect. I had no comorbidities except still being 50# overweight. I search medical journals but "a definitive causal link has not been established'. Because there is a lot of tracking/reporting on GLP1, it is easy to point fingers. Bigger probability, IMO, is rapid weight loss, dehydration, not glp1. I am now down 104#, retired, and in better health then when I was 25. I suspect doctors are covering their behind.... I do nutritional blood tests every 4-5 months and nothing abnormal except for slightly high Ketones as I focus on eating proteins.
 
re NAION: after one year on Tirz, down 60#, I suddenly lost vision in left eye: bottom half went blank, like a curtain pulled up, for about 4-5 minutes. I was outside, soldering a few wires. Nothing extraneous. Eye doctor called it NAION, and told me to stop Tirz (I did not). According to her, this was a known side effect. I had no comorbidities except still being 50# overweight. I search medical journals but "a definitive causal link has not been established'. Because there is a lot of tracking/reporting on GLP1, it is easy to point fingers. Bigger probability, IMO, is rapid weight loss, dehydration, not glp1. I am now down 104#, retired, and in better health then when I was 25. I suspect doctors are covering their behind.... I do nutritional blood tests every 4-5 months and nothing abnormal except for slightly high Ketones as I focus on eating proteins.

What was the outcome of the NAION for you?

Can you expound on the nutritional blood tests?
 
What was the outcome of the NAION for you?

Can you expound on the nutritional blood tests?
Vision came back after 4-5minutes. Was told I was lucky as it could have been permanent. Quest has common cmp/cbc tests, lipid, etc and also thyroid markers (TSH, T3, and T4), nutrition markers (ferritin, vitamin D, vitamin B12, and folate) and others you can request. Doctors only prescribe 1, maybe 2 such sets in a year. I add my own.
 
Vision came back after 4-5minutes. Was told I was lucky as it could have been permanent. Quest has common cmp/cbc tests, lipid, etc and also thyroid markers (TSH, T3, and T4), nutrition markers (ferritin, vitamin D, vitamin B12, and folate) and others you can request. Doctors only prescribe 1, maybe 2 such sets in a year. I add my own.

Fantastic that it didn’t kill nerve endings!


I thought you were talking about some blood tests I hadn’t came across yet.

I enjoy discounted blood work, even better when it goes on sale and I can stock up!😂

1782438828146.webp
 
Vision came back after 4-5minutes. Was told I was lucky as it could have been permanent. Quest has common cmp/cbc tests, lipid, etc and also thyroid markers (TSH, T3, and T4), nutrition markers (ferritin, vitamin D, vitamin B12, and folate) and others you can request. Doctors only prescribe 1, maybe 2 such sets in a year. I add my own.
do you happen to know your cup to disc ratio (eyes)? any bp meds? this is so scary and is the reason im coming off of tirz, even though i have no co-morbidities other than high bmi (normal a1c, no bp meds, unknown cup to disc ratio) i think 🙁
 
no cup to disk ratio number. No med's for anything. A good old friend had similar eye event in his 30's. Doc said he needed to stop smoking, as it kept his blood too thick. NAION is a sort of small blood clot/lack of oxygen. "is often called an "eye stroke" because it results from a sudden loss of blood flow to the optic nerve". Was I dehydrated? possible. Blood pressure drop? possible as bp is now ~100/60 (was 145/90). I will never know the answer.
 

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