Thinking about switching to Sema from Reta

[kagami00]

Hi, right now I am using Reta (3mg per week) and at the beginning (1mg) everything was great, I was able to edge my weightloss results so long!! But now it feels like if I am not feeling anything at all, thats why I am thinking about titrating to 4mg per week.

But my resting heart rate went up so much, by like 20 and I dont want that. Thats why I am thinking about switching to Sema, when I start my next diet. Which dosage should I start with, and what can I expect from Sema compared to Reta?

Thanks in advance!!

 

[HereKittyKitty]

I hope you receive helpful guidance. No experience with Rita so I don't have anything to offer except support.

 

[5byfive]

I'm not the biggest fan of Reta overall, it is hard on the system and I think more than most people need. It has its place, but I feel that Tirz is probably better for most people. Going to Sema does not make sense. More sides and less effect. Swapping to Tirz seems like the move. You may get some HR increase (or in this case not quite a return to base) but it is much less than Reta and studies seem to show it returning to base over around six months. Tirz will almost definitly give you less sides than Sema.

I would start low, appetite suppression will start at a much lower does than with Reta. If I were making that switch, I'd probably start with dropping my Reta down to 1mg again and adding 1mg of Tirz and go from there. You could keep the low doses of both if it works for you (I do think Reta can work well in a stack) or continue to drop Reta as you come up on Tirz.

 

[5byfive]

I hope you receive helpful guidance. No experience with Rita so I don't have anything to offer except support.

Who's this Rita chick and what does she have to do with anything? 😛

 

[rmhla]

Grok says,

Typical patterns:

First few weeks after a dose increase: heart rate may rise noticeably.

After several weeks to a few months: many people see the increase lessen.

Some people: continue to have a resting heart rate that stays a few beats per minute higher than before treatment.

When I first used reta it was 2mg and my heart rate increased by 17 , i stayed the course and after 7 to 10 days it went to 4 or 5 abive ny normal. (I track everything with monitor abs record it, now directly into Grok)

Sure you can bounce to sema but tons of sides with it, Trizepatide as poster above stated much less sides and works well for many.

Personally id stick with Retatrutide at 2mg for 2 weeks then move to 3 for 2 weeks. See what happens and at the same time record your heart...

Many people dont want to wait. Its not a race theres no need to keep up with tic tok or IG.

Great post!

 

[BrightCandle]

I don't see the point of sema now for most people, its not really cheaper and its half as effective as Tirz. About the only reason to use it is issues with GIP agonism, which for some might be interrupting the effectiveness of the contraceptive pill although the data isn't clear yet.

 

[gusterbuster]

Maybe another route is to stack reta with sema. Reta at a tolerable dose for metabolic goodies and add sema for appetite suppression. Reta is a weak GLP, but strong GIP with Glucagon. Sema is a strong GLP.

 

[FunkyOtter]

Maybe another route is to stack reta with sema. Reta at a tolerable dose for metabolic goodies and add sema for appetite suppression. Reta is a weak GLP, but strong GIP with Glucagon. Sema is a strong GLP.

That is actually what brought me here and I am glad to hear you say that. I have done sema and love the appetite suppression of it. I would consider slowly adding R to try to get the best of both worlds, but wasn't sure if it was doubling up on the GLP unnecessarily.