Tiny bit remaining in vial

[Approach]

Is it recommended - to use the remaining drops of the the peptide solution in the vile? Or, throw it away and start a new vile?

Basically, I'm wondering if the concentration of the GLP1 solution would be too strong (bottom of vile)? Ty!

 

[RedSkip]

I just cut the lid off mine and used an extra syringe to pull from the corner of the vial this morning.

I don’t believe the concentration is any higher than previous doses. Each time I gently swirl the vial to “mix” before drawing a dose. Therefore it’s unlikely that the bottom is more concentrated as the volume is drawn down.

 

[brentm]

I don't think the remainder is any less/more strong than the rest.

I always try to use it all. Either by removing the lid or pulling the syringe out just enough to gobble it up on the draw. Usually end up with a bunch of air to flick/push out of the syringe.

 

[dionysos]

I don't think the remainder is any less/more strong than the rest.

I always try to use it all. Either by removing the lid or pulling the syringe out just enough to gobble it up on the draw. Usually end up with a bunch of air to flick/push out of the syringe.

Same method here! I bought a vial de-capper, used it once or twice and found it annoying.
Using only a little care I back the syringe needle out half its length and truly get the last drops out of every vial.

 

[moonpies4misfits]

pulling the syringe out just enough to gobble it up on the draw.

This is what works for me. The amount left over when doing this is negligible.

 

[Bacchus]

Pulling the cap off to get an additional couple units makes sense if you are buying brand name medicine paying an absurd price per mg. But for research peptides and china import, it seems like more work that it’s worth

 

[brentm]

Same method here! I bought a vial de-capper, used it once or twice and found it annoying.
Using only a little care I back the syringe needle out half its length and truly get the last drops out of every vial.

That and I think I dulled the needle hitting the bottom of the vial popping the top off.

 

[mostlydamp]

That and I think I dulled the needle hitting the bottom of the vial popping the top off.

Yep I've dulled it doing that before and injecting felt like jabbing a stick through my skin. I still did it but it was not a fun experience

 

[Gwenhwyfar227]

I personally angle the needle a bit to the side. Pull it way down and get the last out🤷‍♀️

 

[Sheldor]

Pulling the cap off to get an additional couple units makes sense if you are buying brand name medicine paying an absurd price per mg. But for research peptides and china import, it seems like more work that it’s worth

I don't agree that is not wortk. Depending what you take and how many vials you have, you can save over time a little bit. Times are hard, nothing to give away 😄

 

[Gwenhwyfar227]

I don't agree that is not wortk. Depending what you take and how many vials you have, you can save over time a little bit. Times are hard, nothing to give away 😄

Right!! I agree...i am not throwing my money away! Lol

 

[SLZRdad]

I take vial lids off with this

 

[Approach]

Right!! I agree...i am not throwing my money away! Lol

I agree about the money - but, my main point was about the peptide solution iteself. ie, Is the remaining solution a higher concentration? ie) Do some ingredients "settle" on the bottom of the vile? "If" so, then the this dose is different (higher concentration) than previous injections from the same vile. The majority of you think it's a negligible difference. I'm happy to hear this.

 

[Bacchus]

I agree about the money - but, my main point was about the peptide solution iteself. ie, Is the remaining solution a higher concentration? ie) Do some ingredients "settle" on the bottom of the vile? "If" so, then the this dose is different (higher concentration) than previous injections from the same vile. The majority of you think it's a negligible difference. I'm happy to hear this.

The drug and filler is designed to dissolve evenly. Kinda like how there probably is a negligible difference in the amount of sugar in a glass of coke from a newly opened bottle vs a half full one that has been in the fridge for a couple days 😉

 

[Gwenhwyfar227]

I agree about the money - but, my main point was about the peptide solution iteself. ie, Is the remaining solution a higher concentration? ie) Do some ingredients "settle" on the bottom of the vile? "If" so, then the this dose is different (higher concentration) than previous injections from the same vile. The majority of you think it's a negligible difference. I'm happy to hear this.

No it is not any different from what I have experienced. If anything i would think it is lower. As time goes it loses some of its potency

 

[Bacchus]

No it is not any different from what I have experienced. If anything i would think it is lower. As time goes it loses some of its potency

Potency loss is a lot slower than people tend to think. It’s more like a practical excuse for suppliers to be able to blame shipping/storage (in the case of sema tirz and reta). Some peptides, like hgh degrades significantly faster

 

[dionysos]

I agree @Bacchus , reconstituted peptides under refrigeration last quite a long time. I've used 90-day old Semaglutide with no perceptible diminution in effectiveness compared with freshly reconned Sema from the same batch.

An experiment I once read measured UN-REFRIGERATED reconstituted peptides for efficacy at 30, 60 & 90 days. The loss at 30 days of ROOM TEMPERATURE was less than 1%, at 60 days it lost 6%, and at 90 days the sample measured an efficacy loss of 16% - certainly THAT last would be very noticeable.

It is reasonable to assume that REFRIGERATED reconned short chain peptides would degrade far less than that. I've not yet found a proper study that is relevant to our particular use case however.

 

[Bacchus]

I agree @Bacchus , reconstituted peptides under refrigeration last quite a long time. I've used 90-day old Semaglutide with no perceptible diminution in effectiveness compared with freshly reconned Sema from the same batch.

An experiment I once read measured UN-REFRIGERATED reconstituted peptides for efficacy at 30, 60 & 90 days. The loss at 30 days of ROOM TEMPERATURE was less than 1%, at 60 days it lost 6%, and at 90 days the sample measured an efficacy loss of 16% - certainly THAT last would be very noticeable.

It is reasonable to assume that REFRIGERATED reconned short chain peptides would degrade far less than that. I've not yet found a proper study that is relevant to our particular use case however.

From what I know, 120days refrigerated after reconstitution should be close to no loss in potency (unless it’s contaminated) - something like a couple %

 

[dionysos]

From what I know, 120days refrigerated after reconstitution should be close to no loss in potency (unless it’s contaminated) - something like a couple %

That is consistent with what I have seen for myself Bacchus.

I don't recommend that researchers deliberately store reconned peptides that long;
I also don't believe they should be concerned about refrigerated peptide storage longer than 60 or 90 days.