Tirz was fine, Lost 60 lb, Tried reta...

J Arbey

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Tirz was fine ( even up to 15mg/week ), Lost 60 lb in just over a year; Tried Reta for a month --> Can't get quality sleep.

I waited until I was 10 days past my Tirz dose and pinned 1mg Reta, then waited 3 days, pinned 1mg Reta.

Pinned a total of 5mg split up over 2.5 weeks, then pinned 4mg... Definite food noise suppression, slightly more nausea than Tirz for me...
But sleeping was not good, I would wake up at 2-3AM feeling wired, and I only have 2 cups of coffee in the AM, max.

Decided Reta didn't like me; 2 weeks after last Reta I went back to Tirz at 8mg. Have been sleeping much better the last few days. Only a few more pounds to go.

This is research. Sometimes you get great results, sometimes not so good. Everyone can be different.

YMMV

Be safe all.
 
That sucks. I love Reta. So much better. I use a little Tirz still too. I love how vascular Reta makes me and especially during my lifting. Crazy.

Bill
 
I think Reta raises your resting heart rate. My dr. told me that. I think Tirz does it also, but less. Could that be causing your sleep issue?
 
I found on a YouTube a guy said he had to have carbs before bed and it fixed the Reta sleep issues

I now have a snack when I wake up at night. Pumpkin seeds and peanut butter on bread.

Little carbs, little magnesium.

So far so good
 
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I ran out of compounded sema in December, got my first gray reta in Februaray. I was having hair loss over the two years I took official wegovy and zepbound then compounded. Hair is amazingly growing back now.

As for sleep, I'm a night person, go to sleep around 2am and used to be able to sleep in as long as I wanted. Sleeping until noon was great for me.
Now something wakes me up at 6-8am and there is no way I can fall asleep again.
I get good quality sleep according to my galaxy watch but only 4-5 hours.
I don't feel tired at all, even at bedtime.
 
My assumption is that the glucagon agonism of reta causes a general increase in sympathetic nervous system activity, that causes the increased heart rate and presumably is also responsible for the reports of insomnia from it. The increased heart rate itself is not causing it but the increased adrenaline and noradrenaline activity is.
 
I have awful sleep on Reta. Took me way to long to understand a correlation. I was also getting very ‘down’ and the skin thing also. Was crazy. I didn’t take a shot for almost 20 days and then took a smaller dose. That was 2 days ago.

Hoping to be able to keep it (along with daily GHK-cu & KPV). I like how it works other than that. Like a lot.
 

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