Tirzepatide shown to help reduce sleep apnea severity.

Obstructive sleep apnea often is due to being overweight. So weight loss is likely going to have multiple health related benefits like reduction of OSA.
 
I've used a CPAP successfully for several years to treat my severe sleep apnea.
With CPAP therapy my 62 Obstructive Sleep Apneas per Hour (untreated) is reduced to a very, very low 0.4 OSA/hour.

Semaglutide has enabled me to lose over 20% of my bodyweight in the past year.
Now I use 38% LESS PRESSURE and keep my OSAs NEAR ZERO!
Those who don't use CPAP won't know this but a 38% reduction in mask pressure is a HUGE amount.

I've spent the past month transitioning to Tirzepatide @ 7.5mg weekly.
Will Tirz decrease my OSAs and allow further pressure reductions? I'll keep you updated :)
 
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This is an interesting article, but I'm thinking that it's not so much the tirz that's directly causing fewer OSAs, but the fact that subjects lost 20% of their weight. What I'd really like to see is the same study repeated with subjects who lost that amount of weight via other meds or gastric bypass, etc.
 
I've used a CPAP successfully for several years to treat my severe sleep apnea.
With CPAP therapy my 62 Obstructive Sleep Apneas per Hour (untreated) is reduced to a very, very low 0.4 OSA/hour.

Semaglutide has enabled me to lose over 20% of my bodyweight in the past year.
Now I use 38% LESS PRESSURE and keep my OSAs NEAR ZERO!
Those who don't use CPAP won't know this but a 38% reduction in mask pressure is a HUGE amount.

I've spent the past month transitioning to Tirzepatide @ 7.5mg weekly.
Will Tirz decrease my OSAs and allow further pressure reductions? I'll keep you updated :)
This is a fantastic result - congratulations!
 
HOL UP!
I don't see that this study reveals the effect of Tirzepitide alone on AHI (OSAs)
as distinct from the effect of bodyweight reduction alone on OSAs.

SURMOUNT 2 - CPAP USERSAHI CHANGE 52nd WEEKBODYWEIGHT CHANGE %
Tirzepatide-30.4-20.1
Placebo

-2.3 %

-2.3 %

Quite the contrary finding I think.
SURMOUNT 2 - CPAP USERS
BODYWEIGHT CHANGE %AHI CHANGE %
Tirzepatide-20.1-62.8
Placebo-2.3-6.3

CPAP users who received a Placebo and lost 2.3% of their bodyweight during the study
had a 6.3% reduction in OSA. I would say this study indicates suggests that bodyweight reduction alone reduces AHI.
Certainly Tirzepatide makes weight loss far easier to achieve, and I am grateful for that! However, let's not oversell the benefits.

I'm a CPAP user who lost 20% bodyweight using (primarily) Semaglutide. I doubt that switching to Tirzepatide will provide ADDITIONAL OSA reduction apart from that achieved by further weight loss. There is no evidence in this study to persuade me that it would.

Said differently: IMO at my goal weight, in maintenance at a fixed weight, and experiencing a consistent measured rate of OSAs - switching to Tirzepitide from Semaglutide would cause no reduction in OSAs.
 
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