Tirzepatide + weed — anyone else deal with this?

[gurbert]

Tirz has been a game changer for appetite control — the food noise is basically gone and I rarely think about over-eating. But the second I smoke, all of that goes out the window. Full munchies mode, like the medication isn't even there.


Anyone else experience this? Curious if it's a common thing or just me. And for those who've figured out how to manage it — how are you controlling appetite/cravings when you're high without just white-knuckling it?

 

[AlexSilver]

On Reta I have that, I just eat a couple complex carbs and it goes away. I can fix it with 2 crackers.

 

[Mayostardayonnaise]

That is how it has worked for me so far as well. I’ve been on Tirz for 7 months, using thc gummies for 4 of those months, and smoking in particular for the last month or so. I do want to cut down to twice a week, however I have been able to fix the munchies with healthy snacks/a pretty minimal amount of food compared to being high off of Tirz. Everytime that happens, I have carrot sticks, low cal crackers, anything low cal with a crunch, because I might do a lot of crunchin. It also seems like the munch feeling maybe isn’t as strong as it would be, but it’s definitely still there. It’s occasionally caused me to eat 150 calories or so over what I want to for the day, but I end up eating lighter in the day if I know I’ll have a munch that night.

 

[xgirlmama]

My father-in-law is on Tirz for both diabetes and weight loss and smokes pot every Friday. And every Saturday he tells us he has regrets because the pot overrides the food control and goes hog wild with eating

 

[peppystrings80]

No, but I am a pretty heavy cannabis user and have never really gotten the munchies from it anyway. It just helps with my aches and pains and my mood. I haven't noticed much difference, personally. Maybe you just need to smoke more weed! Lol. Kidding, kind of.

 

[chewonmysac]

I smoke a Pre-roll a day, and it keeps the Dr. away. Weed is the original Peptide.

 

[Ragnar]

This is an interesting study that helps explain the interaction of cannabis and hormones related to appetite. They had a trend for changes with glp1 (p 0.08) related to cannabis use but significance for other hormones.
I won’t list all the findings but the following sums it up “In conclusion, cannabis administration in this study modulated blood concentrations of some appetitive and metabolic hormones, chiefly insulin, in cannabis users”

Effects of oral, smoked, and vaporized cannabis on endocrine pathways related to appetite and metabolism: a randomized, double-blind, placebo-controlled, human laboratory study - PMC

As perspectives on cannabis continue to shift, understanding the physiological and behavioral effects of cannabis use is of paramount importance. Previous data suggest that cannabis use influences food intake, appetite, and metabolism, yet human ...

pmc.ncbi.nlm.nih.gov

 

[libertarianguy]

Tirz has been a game changer for appetite control — the food noise is basically gone and I rarely think about over-eating. But the second I smoke, all of that goes out the window. Full munchies mode, like the medication isn't even there.


Anyone else experience this? Curious if it's a common thing or just me. And for those who've figured out how to manage it — how are you controlling appetite/cravings when you're high without just white-knuckling it?

Ayo waddup Stavvy!

 

[thatkatmat]

I smoked weed for 45 years before I started Tirz (I'm 59), The day I started I stopped smoking. Reading this makes me think I made the right decision. The cool thing about quitting weed while on Tirz is that I have zero cravings for it, (Like Sugar or beer) maybe I'm just lucky, I don't know but, man, I love Tirzepatide!

 

[Romulusguy]

Tirz has been a game changer for appetite control — the food noise is basically gone and I rarely think about over-eating. But the second I smoke, all of that goes out the window. Full munchies mode, like the medication isn't even there.


Anyone else experience this? Curious if it's a common thing or just me. And for those who've figured out how to manage it — how are you controlling appetite/cravings when you're high without just white-knuckling it?

Wow, I was happy to see this post 🙂 I live in California, so marijuana is 100% legal here to purchase, grow, and use. I am a heavy user, and it definitely has led to me being overweight due to the "munchies" and everything tasting so good while buzzed. I was prepared to abstain while on tirz for the duration of my weight loss journey, but........as it turns out, the tirz 100% suppresses the munchies in me, even while buzzed!


Everyone reacts differently to weed AND tirz, but in my case, the munchies while on thc are GONE while using tirz.

 

[RoyGBiv]

Tirz has been a game changer for appetite control — the food noise is basically gone and I rarely think about over-eating. But the second I smoke, all of that goes out the window. Full munchies mode, like the medication isn't even there.


Anyone else experience this? Curious if it's a common thing or just me. And for those who've figured out how to manage it — how are you controlling appetite/cravings when you're high without just white-knuckling it?

Hey I'm a heavy guy I've been on the road for sometime. I'm not on GLP's as of yet but I have been using gummies for some time now to mitigate stress. I was definitely a munch monster with regular THC both Inda and Sati.. however I was introduced to some Inda's that have a 5-1-1 ratio the 5 being CBG and it just helps me relax and makes me want to pass out after about 2 hours and I don't get munchies or over eat at all. Just thought I'd share. Its worth a try.

 

[gurbert]

Wow, I was happy to see this post 🙂 I live in California, so marijuana is 100% legal here to purchase, grow, and use. I am a heavy user, and it definitely has led to me being overweight due to the "munchies" and everything tasting so good while buzzed. I was prepared to abstain while on tirz for the duration of my weight loss journey, but........as it turns out, the tirz 100% suppresses the munchies in me, even while buzzed!


Everyone reacts differently to weed AND tirz, but in my case, the munchies while on thc are GONE while using tirz.

I’m happy for you but at the same time fuck you.

It suppressed hunger for me the first couple times but then it stopped. Tirz works great without weed, but I swear weed has gotten 100x more potent too so there’s that.

 

[gothsoup]

Wow, I was happy to see this post 🙂 I live in California, so marijuana is 100% legal here to purchase, grow, and use. I am a heavy user, and it definitely has led to me being overweight due to the "munchies" and everything tasting so good while buzzed. I was prepared to abstain while on tirz for the duration of my weight loss journey, but........as it turns out, the tirz 100% suppresses the munchies in me, even while buzzed!


Everyone reacts differently to weed AND tirz, but in my case, the munchies while on thc are GONE while using tirz.

I am truly so jealous of you. My munchies never go away. lol

 

[Pepito_Peptide]

Tirz (Mounjaro) isnt working when i vape Weed, i try to fix it with healty options

 

[HoopFan]

My friend keeps complaining that Tirz is not working for her. She is only on month two and is about to bump to 6 mg every five day. She also smokes weed daily and works at a bar with a full kitchen.

Sometimes you just can’t out Tirz the smoke, and gotta pick a side.

 

[gurbert]

My friend keeps complaining that Tirz is not working for her. She is only on month two and is about to bump to 6 mg every five day. She also smokes weed daily and works at a bar with a full kitchen.

Sometimes you just can’t out Tirz the smoke, and gotta pick a side.

I had to put two new holes in my belt, needless to say I've stayed away from weed, not that I smoked a lot anyways....

I just increased to 6mg (3mg monday / 3mg friday), but I'm on my 11th week and this was my first week increasing from 5mg -> 6mg.

 

[jungletech]

Hey I'm a heavy guy I've been on the road for sometime. I'm not on GLP's as of yet but I have been using gummies for some time now to mitigate stress. I was definitely a munch monster with regular THC both Inda and Sati.. however I was introduced to some Inda's that have a 5-1-1 ratio the 5 being CBG and it just helps me relax and makes me want to pass out after about 2 hours and I don't get munchies or over eat at all. Just thought I'd share. Its worth a try.

What strains?

I lose weight when I quit weed, unfortunately.

 

[RoyGBiv]

What strains?

I lose weight when I quit weed, unfortunately.

Hey JT,

Its Mostly Sativa dormant Hybrid Blue I believe they said. Its mostly concentrated on the CBG focus cannabigerol.. its considered the mother of all compounds in weed. I get way les munchies but can during the day. However I mostly use an hour and half before bed now days. It drastically improves my pain while sleeping and keeps me asleep. i used to wake every 2 hours.
I believe the manu is Illicit. Cheers!