To filter or not to filter, that is the question

[hexagonal]

Yep. Purity tests are about looking at the state of the peptide. Degraded aggregates, incomplete synthesis, etc. The way the tests work doesn't allow for it to test for purity in the way people tend to think.

On Peptide Purity | TrustPointe Analytics LLC

Updated: 25-Oct-2024 While identity, quantity, and sterility are straightforward and critical, purity is not something t

trustpointeanalytics.com

 

[Wheatthins]

Wow, not gonna lie. I completely misunderstood how the testing worked. Kinda freaks me out a bit.

 

[penewbie]

Wow, not gonna lie. I completely misunderstood how the testing worked. Kinda freaks me out a bit.

It's a super common misconception, and nobody is born with this knowledge.

 

[raw_oyster_eater]

in reality almost none of us filter. and in my opinion you're more likely to screw something up or dump a vial screwing around.

 

[penewbie]

in reality almost none of us filter. and in my opinion you're more likely to screw something up or dump a vial screwing around.

Is there a forum poll on this matter?

Because I am certain "almost none" is completely wrong.

 

[raw_oyster_eater]

Is there a forum poll on this matter?

Because I am certain "almost none" is completely wrong.

yea, you go grab that.

 

[penewbie]

yea, you go grab that.

Not the man with holes in his stomach being sarcastic about safety precautions.

 

[Yankeegurl_LQJ]

I dont bother filtering. Imo if it's lyophilized it's already filtered and sterile enough for me. Ive done worse. I've already died (twice). I'll take my chances.
☆I respect that that everyone does not feel the same as I do. We are all entitled to our own thoughts opinions.

 

[Wheatthins]

I dont bother filtering. Imo if it's lyophilized it's already filtered and sterile enough for me. Ive done worse. I've already died (twice). I'll take my chances.
☆I respect that that everyone does not feel the same as I do. We are all entitled to our own thoughts opinions.

Thanks for those screenshots, My immediate thought was heavy metals. That eases my mind somewhat but I still might look into filtering. I'm not in the medical field or a chemist so there is a lot I'm still learning.

 

[nonyabizznez]

Liver transplant $878,400+ (I've had one)
Filter .90¢
Tacrolimus for life = low immunity.

I took enough risks destroying my first liver. Personally I'm okay with a cheap precaution.

 

[GimmeABreak]

I am beginning to think that I get fewer ISR's when I filter. I'm trialing this hypothesis with SS31 today, I had to stop pinning it because the ISR's would burn/itch for like a week. They usually hit about a day after I pin. After a two-week break I filtered a fresh vial and hopefully, no ISR tomorrow.

I was limiting filtering to anything I put into a cart because it will be around more than just a few days. I might start filtering everything to see how I fare.

 

[Mr. Smith]

Liver transplant $878,400+ (I've had one)
Filter .90¢
Tacrolimus for life = low immunity.

I took enough risks destroying my first liver. Personally I'm okay with a cheap precaution.

100% with you!!! Why take any additional risk. 90 cents isn't much to pay.

 

[Mr. Smith]

Some new info. Jano filters with .22 before testing.

 

[bguz1200]

I've only been filtering my tirzepatide, because that's what I've read about.

Do you all filter your GLOW? Haven't done enough research to understand if it's OK or not (meaning if using .22 filter will not mess with the compound effectiveness).

 

[raw_oyster_eater]

Some new info. Jano filters with .22 before testing.

i don't like that. test it they way you get it.

 

[penewbie]

i don't like that. test it they way you get it.

They can't.

If there's any (relatively) large particulate matter in the vials it's going to get stuck in the columns and ruin them. It won't show up on the HPLC either way, but this way it will also cost thousands to fix.

(Paraphrasing from memory their explanation, this is the limit of my understanding).

 

[raw_oyster_eater]

OK thanks for the explanation.

 

[ghreid]

Thanks for this post. Had not been filtering but after reading up on the subject due to these posts, I have ordered filters starting asap. small price for peace of mind. As a doc I am always reminded "do no harm".

 

[raw_oyster_eater]

i wonder if cheap filters could actually contaminate your peps.

 

[noggin]

I see some discussion about filtering peptides. If they are 99% pure, then what are you filtering out? One of my worries is introducing a contaminant.

All the testing facilities filter first before testing the purity. Besides that, they are testing the purity out of just the peptides present, not all the substance in there (of which only 1% might be peptides)