Unconstitued Reta Freezing Yes Or No

[Phatmax]

Hi all I'm getting mixed answers on this and now not sure if i have unconstituted raw Reta how is best to store it I've been told to freeze it in Ziplock bags until I need it reconstituted then once its reconstituted keep in fridge?

thanks for your help as always guys.

 

[indolent]

Yes, unreconstituted retatrutide and other GLP-1s are best kept in the freezer (any one, including household ones with autodefrost) for longer and more sterile lifespan. For up to several years. You don't need any special kind of bag or box, although if your area is prone to blackouts a thermal container with icepacks would be helpful to avoid big thaw/freeze swings.

 

[Phatmax]

Yes, unreconstituted retatrutide and other GLP-1s are best kept in the freezer (any one, including household ones with autodefrost) for longer and more sterile lifespan. For up to several years. You don't need any special kind of bag or box, although if your area is prone to blackouts a thermal container with icepacks would be helpful to avoid big thaw/freeze swings.

thank you 👍

 

[byefatlicia]

Hi all I'm getting mixed answers on this and now not sure if i have unconstituted raw Reta how is best to store it I've been told to freeze it in Ziplock bags until I need it reconstituted then once its reconstituted keep in fridge?

thanks for your help as always guys.

When you say "raw" do you mean a lyophilized kit?

 

[Batscout]

Hi all I'm getting mixed answers on this and now not sure if i have unconstituted raw Reta how is best to store it I've been told to freeze it in Ziplock bags until I need it reconstituted then once its reconstituted keep in fridge?

thanks for your help as always guys.

I am not sure how there could be mixed answers as to whether lyophilized peptide vials should be stored in the freezer. The universal answer should be yes. Reconstituted vials with liquid should be refrigerated and is not necessary to freeze a lyophilized vial if you plan to use it in a month or two. Perhaps that is where the mixed signals came from?

 

[latviantower]

When you say "raw" do you mean a lyophilized kit?

Good question! I always assumed “raw” would be pure reta devoid of fillers, which I’ve never seen but if you had a connection at the factory, I suppose it’s theoretically possible! I’m guessing Phatmax is asking regarding what we all know and love - the lyophilized variety ready to recon and pin.

 

[yrrdead]

I am not sure how there could be mixed answers as to whether lyophilized peptide vials should be stored in the freezer. The universal answer should be yes. Reconstituted vials with liquid should be refrigerated and is not necessary to freeze a lyophilized vial if you plan to use it in a month or two. Perhaps that is where the mixed signals came from?

I would guess that they have seen some of the more in depth posts that I have seen regarding acutal storage temperature requirements as they relate to glass transistion temperature. Where depending on your specific peptide and its specific Tg you could be cycling through that value multiple times in a regular freezer, which is a bad thing.

But then you realize that we don't really know enough about our particular peps so we don't even know what the Tg is anyway.

 

[Gohengrin]

Depends. No, if you want to use it the next 1 to 2 years.

 

[byefatlicia]

Depends. No, if you want to use it the next 1 to 2 years.

Can you elaborate?

 

[Phatmax]

Good question! I always assumed “raw” would be pure reta devoid of fillers, which I’ve never seen but if you had a connection at the factory, I suppose it’s theoretically possible! I’m guessing Phatmax is asking regarding what we all know and love - the lyophilized variety ready to recon and pin.

yes that what i was asking sorry not Raw just lyophilized variety ready to recon and pin.

 

[extropy]

In an interview, Janoshik said that he pulled out decades-old peps from a closet and they tested at reasonably high purity still. He added that in the fridge, they'll all last years. In the freezer, it'll be decades.

 

[libertarianguy]

In an interview, Janoshik said that he pulled out decades-old peps from a closet and they tested at reasonably high purity still. He added that in the fridge, they'll all last years. In the freezer, it'll be decades.

Why would this apply to tirzepatide or retatrutide? Surely different peptides will have different shelf-lives

 

[byefatlicia]

Why would this apply to tirzepatide or retatrutide? Surely different peptides will have different shelf-lives

I think in the same Jano interview, He called Tirzepatide the "cockroach" of peptides.

 

[CNCCurrency]

Why would this apply to tirzepatide or retatrutide? Surely different peptides will have different shelf-lives

Hmm?

 

[Chili777]

Why would this apply to tirzepatide or retatrutide? Surely different peptides will have different shelf-lives

Not really from my research. Not in lysophilized form when stored properly anyway There is more variation when reconstituted, but even then the only one I've read that should be used within 30 days is Mots-C. There is a study on the interwebs that shows it can have a slight 7% degradation at 30+ days. There may be more, but I'm still looking.

I've seen no data on GLPs indicating that limitation and many reports of them being effective after 2+ months in reconstituted form, again, properly stored.

 

[Phatmax]

When you say "raw" do you mean a lyophilized kit?

yes 👍

 

[Phatmax]

thanks all for all the replies that clears that up.. so ill keep any I don't plan on using in the freezer then it will last. what about unused BAC water?

 

[Gohengrin]

thanks all for all the replies that clears that up.. so ill keep any I don't plan on using in the freezer then it will last. what about unused BAC water?

Used bac water, storing at room temp in a cleanish room or cabinet. No fridge or freezer. Use it if possible withing 30 days after drawing from it the first time.
Thats what i researched.