wanting to stack sema with reta

seunoia

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would it be suggested to incorporate both sema + reta at low-mod. dosages of each to reap GIP + Glucagon benefits from reta along with appetite suppression from sema?

on 8mg reta currently, and was curious about doing .25mg (or any amount) sema combined with 2-4mg reta for best of both worlds. i’m still ravenous off high reta doses and appetite is an issue. i want to feel satiated and hell, possibly even avoidant of food, because i always end up overeating. sticking to meal plans was always easy for me, even when initially starting reta and dealing with major suppression. i just ate less and didn’t have a single thought about another bite or a snack in-between.

i’m currently 190 lbs looking to drop 10-12lbs more.

reasons why:
-on my current reta dose and higher dosages, im still able to outeat my damn deficit.
-haven’t been able to sleep on my current reta dose. cortisol is sky high presumably due to RHR increase and glucagon, even with diet breaks.
-slept wonky on tirz aswell.
-reta at high doses (10-12) isn’t the best cost wise long term, and i have a script for ozempic anyways so sema is basically on hand and dirt cheap for me.
-Reta hasn’t given me that true app. suppression. i enjoy the glucagon benefits and also love the 9x stronger GIP factor on it compared to tirz. stacking it with tirz seemed pointless to me
-cagri made me fall asleep behind the wheel and hit a stop sign. NEVER touching it again. calling me a poor responder to it would be an understatement, lol

any advice from people who’ve experimented with stacked GLPs is appreciated. thank you.
 
I wouldn't stack glps, mostly because I don't know enough about it. But if you're looking to speed up weight loss and have better appetite suppression, try adding cagri with reta. A little goes a long way. I'm only running .5mg but it packs a punch
 
would it be suggested to incorporate both sema + reta at low-mod. dosages of each to reap GIP + Glucagon benefits from reta along with appetite suppression from sema?

on 8mg reta currently, and was curious about doing .25mg (or any amount) sema combined with 2-4mg reta for best of both worlds. i’m still ravenous off high reta doses and appetite is an issue. i want to feel satiated and hell, possibly even avoidant of food, because i always end up overeating. sticking to meal plans was always easy for me, even when initially starting reta and dealing with major suppression. i just ate less and didn’t have a single thought about another bite or a snack in-between.

i’m currently 190 lbs looking to drop 10-12lbs more.

reasons why:
-on my current reta dose and higher dosages, im still able to outeat my damn deficit.
-haven’t been able to sleep on my current reta dose. cortisol is sky high presumably due to RHR increase and glucagon, even with diet breaks.
-slept wonky on tirz aswell.
-reta at high doses (10-12) isn’t the best cost wise long term, and i have a script for ozempic anyways so sema is basically on hand and dirt cheap for me.
-Reta hasn’t given me that true app. suppression. i enjoy the glucagon benefits and also love the 9x stronger GIP factor on it compared to tirz. stacking it with tirz seemed pointless to me
-cagri made me fall asleep behind the wheel and hit a stop sign. NEVER touching it again. calling me a poor responder to it would be an understatement, lol

any advice from people who’ve experimented with stacked GLPs is appreciated. thank you.
That's what I've been doing. Here's a link to where I discussed my journey so far including my dosing schedule. ---> here <---

Although in hindsight I do think that my very first dose of reta was .5mg and the following week I upped it to 1mg. My food noise was controlled from the very beginning and I think sema and reta go very well together. You probably don't even need that much and you could drop your reta dose by quite a bit.
 
I wouldn't stack glps, mostly because I don't know enough about it. But if you're looking to speed up weight loss and have better appetite suppression, try adding cagri with reta. A little goes a long way. I'm only running .5mg but it packs a punch
i wish... i mentioned cagri in my post 😅
 
That's what I've been doing. Here's a link to where I discussed my journey so far including my dosing schedule. ---> here <---

Although in hindsight I do think that my very first dose of reta was .5mg and the following week I upped it to 1mg. My food noise was controlled from the very beginning and I think sema and reta go very well together. You probably don't even need that much and you could drop your reta dose by quite a bit.
will read through, thank you!!
 
would it be suggested to incorporate both sema + reta at low-mod. dosages of each to reap GIP + Glucagon benefits from reta along with appetite suppression from sema?

on 8mg reta currently, and was curious about doing .25mg (or any amount) sema combined with 2-4mg reta for best of both worlds. i’m still ravenous off high reta doses and appetite is an issue. i want to feel satiated and hell, possibly even avoidant of food, because i always end up overeating. sticking to meal plans was always easy for me, even when initially starting reta and dealing with major suppression. i just ate less and didn’t have a single thought about another bite or a snack in-between.

i’m currently 190 lbs looking to drop 10-12lbs more.

reasons why:
-on my current reta dose and higher dosages, im still able to outeat my damn deficit.
-haven’t been able to sleep on my current reta dose. cortisol is sky high presumably due to RHR increase and glucagon, even with diet breaks.
-slept wonky on tirz aswell.
-reta at high doses (10-12) isn’t the best cost wise long term, and i have a script for ozempic anyways so sema is basically on hand and dirt cheap for me.
-Reta hasn’t given me that true app. suppression. i enjoy the glucagon benefits and also love the 9x stronger GIP factor on it compared to tirz. stacking it with tirz seemed pointless to me
-cagri made me fall asleep behind the wheel and hit a stop sign. NEVER touching it again. calling me a poor responder to it would be an understatement, lol

any advice from people who’ve experimented with stacked GLPs is appreciated. thank you.
Up until my holiday hiatus a few weeks ago I’ve been consistently pinning .2mg Sema and .7mg Reta per week. I am on Reta because I trust the studies on the neuroprotective effects and Sema to supplement the limited amount of GLP agonist that is present in Reta.

If I increase Sema over .5mg/wk I feel weak and nauseated with horrible sulphuric burps. Adding Reta meant I could drop my Sema dosage. If I could only have 1 if would be Reta due to the comparative binding affinities of GLP, GIP and GCGR. No reason for me to quit Sema though, it helps me keep the Reta low due to the GLP. Stacking is quite common in the longevity and body building community.
 
Up until my holiday hiatus a few weeks ago I’ve been consistently pinning .2mg Sema and .7mg Reta per week. I am on Reta because I trust the studies on the neuroprotective effects and Sema to supplement the limited amount of GLP agonist that is present in Reta.

If I increase Sema over .5mg/wk I feel weak and nauseated with horrible sulphuric burps. Adding Reta meant I could drop my Sema dosage. If I could only have 1 if would be Reta due to the comparative binding affinities of GLP, GIP and GCGR. No reason for me to quit Sema though, it helps me keep the Reta low due to the GLP. Stacking is quite common in the longevity and body building community.
really? such low dosages, i want to stay on low dosages too. how long have you been on both sema and reta?
 
really? such low dosages, i want to stay on low dosages too. how long have you been on both sema and reta?
Beginning of this past August I started Sema, by the end of August I started Reta. I messed up by titrating up too fast a few weeks in not realizing how hard it hits. I got really sick and so I slowed it down. After Thanksgiving I’ll start back at the same dose for Sema and maybe .3 for Reta. I need to gain back about 5 lbs before I start again though. Even though I’ve been off I still find it hard to eat more than a few ounces before I feel full, would like to be able to gorge on Thanksgiving, hopefully my appetite returns by then!
 
Beginning of this past August I started Sema, by the end of August I started Reta. I messed up by titrating up too fast a few weeks in not realizing how hard it hits. I got really sick and so I slowed it down. After Thanksgiving I’ll start back at the same dose for Sema and maybe .3 for Reta. I need to gain back about 5 lbs before I start again though. Even though I’ve been off I still find it hard to eat more than a few ounces before I feel full, would like to be able to gorge on Thanksgiving, hopefully my appetite returns by then!
Some ghrp6 will have you eating the whole turkey lol
 
i wish... i mentioned cagri in my post 😅
Omg I didn't see the last sentence, my bad. So cagri made you crazy tired... There's a potential for that with sema as well. My mom is on sema and she said it makes her brain foggy and she sleeps all the time. It's still worth trying since everyone responds differently.

There's also tesa which a lot of people have said is a godsend as far as jumping that last 10-15 pound hurdle, with some reports of appetite suppression.
 
Some ghrp6 will have you eating the whole turkey lol
😂
Omg I didn't see the last sentence, my bad. So cagri made you crazy tired... There's a potential for that with sema as well. My mom is on sema and she said it makes her brain foggy and she sleeps all the time. It's still worth trying since everyone responds differently.

There's also tesa which a lot of people have said is a godsend as far as jumping that last 10-15 pound hurdle, with some reports of appetite suppression.
currently on tesa, noticed my abs be slightly more visible (im a 12% bf athlete) and it’s definitely helped, but in my case i got hungrier on it lol. i appreciate the suggestions tho!
 
You could try it, why not. If you can't do cag and tirz, then sema is your friend, if you need more glp-1, plus it's cheap.
🙂
going to try it. took my 7mg reta dose yesterday, will add .25 sema midway through the week, and my next weekly reta dose i’ll taper it down to 3-4mg depending on what i see fit. thank you!!
 
I currently stack Reta and Sema - 8mg Reta at the beginning of the week and 1mg Sema before the weekend. I’m a slow responder and started with Sema in February. When I started Reta in July, I titrated Reta up in 4 week intervals while titrating Sema down. I feel like I’ve hit my sweet spot with a consistent 0.75lbs a week loss and good control with minimal side effects. My plan is to keep this up until I plateau, then switch the Sema to Cagri or just increase Reta.
 
Up until my holiday hiatus a few weeks ago I’ve been consistently pinning .2mg Sema and .7mg Reta per week. I am on Reta because I trust the studies on the neuroprotective effects and Sema to supplement the limited amount of GLP agonist that is present in Reta.

If I increase Sema over .5mg/wk I feel weak and nauseated with horrible sulphuric burps. Adding Reta meant I could drop my Sema dosage. If I could only have 1 if would be Reta due to the comparative binding affinities of GLP, GIP and GCGR. No reason for me to quit Sema though, it helps me keep the Reta low due to the GLP. Stacking is quite common in the longevity and body building community.
Want to make sure my reading comprehension is correct, but this is a maintenance dose for you? I have read of others having low maintenance doses for the 'extras' that reta provides. Where as I am taking 6mg a week for weight loss assistance.
 
I currently stack Reta and Sema - 8mg Reta at the beginning of the week and 1mg Sema before the weekend. I’m a slow responder and started with Sema in February. When I started Reta in July, I titrated Reta up in 4 week intervals while titrating Sema down. I feel like I’ve hit my sweet spot with a consistent 0.75lbs a week loss and good control with minimal side effects. My plan is to keep this up until I plateau, then switch the Sema to Cagri or just increase Reta.
how did the initial .25mg of sema feel to you?
 
Want to make sure my reading comprehension is correct, but this is a maintenance dose for you? I have read of others having low maintenance doses for the 'extras' that reta provides. Where as I am taking 6mg a week for weight loss assistance.
No, I started at .25mg Sema and .25mg Reta this August. My BMI was 20-21 when I started, trying like hell to not lose weight but I’ve read countless papers on how GLP, GIP and GCGR agonists can benefit the rest of the body, like being neuroprotective and reducing inflammation. Many in the weight loss community are at war with anybody who wants to titrate down or microdose, insisting it will cause weight gain. I’ve been off for a few weeks and haven’t experienced any of the stuff I was told I would, I’ve heard countless stories like mine as well. I think this is where the “powerless to a disease” group splits off from those who made lifestyle changes and used peptides as a tool to improve health. It’s two completely different groups so they’re going to have a totally different experience.
 
No, I started at .25mg Sema and .25mg Reta this August. My BMI was 20-21 when I started, trying like hell to not lose weight but I’ve read countless papers on how GLP, GIP and GCGR agonists can benefit the rest of the body, like being neuroprotective and reducing inflammation. Many in the weight loss community are at war with anybody who wants to titrate down or microdose, insisting it will cause weight gain. I’ve been off for a few weeks and haven’t experienced any of the stuff I was told I would, I’ve heard countless stories like mine as well. I think this is where the “powerless to a disease” group splits off from those who made lifestyle changes and used peptides as a tool to improve health. It’s two completely different groups so they’re going to have a totally different experience.
yeah. wanting to keep low dose reta year round for the same benefits you mentioned.

BTW is there any advice for initially starting sema that anyone can give? going to add it in within 3 days. wanna make sure i dont have insane nausea or do something wrong off .25mg lol.
 
yeah. wanting to keep low dose reta year round for the same benefits you mentioned.

BTW is there any advice for initially starting sema that anyone can give? going to add it in within 3 days. wanna make sure i dont have insane nausea or do something wrong off .25mg lol.
The only advice I give is start low and titrate slow. If you feel it’s not working then increase the tiniest amount and wait a few days. We all have different responses but you don’t want to over-do it or you’ll be miserable. If you are good at .25mg/wk, stay there until you need more, then I would do a split of .15/.15 every 3-4 days. If you need more do the math and figure out how to bump up slowly by doing smaller and more frequent injections. I thought I was going to pin 2-3mg/wk like a hero and blasted multiple doses a few weeks in - MUCH REGRETS.
 

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