Warning - QSC's NAD+ is bad

TessaM

TessaM

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Multiple users now are reporting that it has a super low pH -- around 2.5, which would be like injecting vinegar. One person could barely weight-bear on their leg for a week after injecting it.

This is not how it should normally be, peptides should be buffered during manufacture. If you inject this shit it will cause intense pain and radiating tissue damage, and that will last weeks+. The only study I could find that tested the injection of super low pH solutions into volunteers stopped at pH 3.0 for ethical reasons. Volunteers rated the pain as "excruciating."

Get litmus strips to test it. If it's acidic, throw it out.

QSC is so far ignoring the problem.
 
I tried it. Yeah. It sucks. Bad injection site reaction. Swelled up really good. SQ super bad. IM better but it still sucks. It’s true. Don’t buy it. I hope they fix it. I’m planning to get a vial from peptide sciences to see what it’s supposed to be like…
 
TessaM said:
Multiple users now are reporting that it has a super low pH -- around 2.5, which would be like injecting vinegar. One person could barely weight-bear on their leg for a week after injecting it.

This is not how it should normally be, peptides should be buffered during manufacture. If you inject this shit it will cause intense pain and radiating tissue damage, and that will last weeks+. The only study I could find that tested the injection of super low pH solutions into volunteers stopped at pH 3.0 for ethical reasons. Volunteers rated the pain as "excruciating."

Get litmus strips to test it. If it's acidic, throw it out.

QSC is so far ignoring the problem.
Click to expand...

NAD+ is acidic either if you brew it or you make it in lyophilised form, it has nothing to do with the process of production, you can mix it with a basific solution instead of bac water to make the pH higher.

That said it's the first time we produce this product, and there is room to improve.

Saying that we are ignoring the problem is stupid, because you were posting about the problem and tagging me where I cannot post, sources cannot post outside the UG forum. Maybe if you contacted me about it or mentionned in my thread, you will get an answer.
 
Qingdao Sigma said:
NAD+ is acidic either if you brew it or you make it in lyophilised form, it has nothing to do with the process of production, you can mix it with a basific solution instead of bac water to make the pH higher.

That said it's the first time we produce this product, and there is room to improve.

Saying that we are ignoring the problem is stupid, because you were posting about the problem and tagging me where I cannot post, sources cannot post outside the UG forum. Maybe if you contacted me about it or mentionned in my thread, you will get an answer.
Click to expand...
It was mentioned in your thread multiple times, starting from the first report months ago. But glad you finally replied here.

Spoke with a medical clinic that offers it and no, they do not need to reconstitute it with anything but saline.

Definitely room for improvement, as that's pretty poor quality control esp for a new batch of something never before offered. Hopefully the next batch won't accidentally hurt or maim people. 👍
 
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Based on what Jano said regarding peptides and ph it sounds like the engineer at QSC might need to tinker around with the buffering of the solution prior to lyophilization to make it less acidic.

I'm curious if anyone has tried any of the highly alkaline BAC that's been discovered recently to see if that results in a more neutral ph after reconstitution.
 
Cool. Will give it a try. I’ve got quite a bit left and I don’t want to throw it away
 
Has anyone heard if anyone getting the NAD+ tested. I tested the PH and it was 3.0.
 
CallieKat said:
I tried it. Yeah. It sucks. Bad injection site reaction. Swelled up really good. SQ super bad. IM better but it still sucks. It’s true. Don’t buy it. I hope they fix it. I’m planning to get a vial from peptide sciences to see what it’s supposed to be like…
Click to expand...
I've used peptide sciences and it is way better. Initially it stings but nothing like the pain from the QSC's NAD+. I did it IM and my entire area and shoulder were killing me. Both SubQ and IM sucked! I'm done with this product. Sadly, they are not refunding or exchanging.
 
ZippityDooDah said:
Pretty much anything that isn't Pfizer/Hospira brand, like everything on Amazon. Probably a good idea to order some good aquarium test strips at the same time.
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What would the PH level be for a highly alkaline bac water? The one I used on Q's NAD+ around 6PH and after mixed it read a ph of 3
 
Over 48 hours no reaction! Not sure what I’m looking for in terms of efficacy though. I’m cycling off Semax/Selank now and I think I feel a little slower…
 
SubQ 25 mg twice a week. So many different protocols out there. I should probably increase next week…
 
Isn't this well known about NAD+ ?? Why would anyone inject before checking the pH or confirming if it was buffered ahead of time. Some people add sodium bicarbonate to buffer at home.

However! There are sellers of already buffered NAD+. Look for them and don't waste your time playing chemist.
 
Most NAD+ has been sold with low pH. I tried three from different vendors and they all have too low pH.

But like others have said, they can buffer the excipients to correct the pH.

PGB NAD+ is buffered and I have no pain or discomfort with it.

This just needs to be way going forward.
 
Vicki said:
Isn't this well known about NAD+ ?? Why would anyone inject before checking the pH or confirming if it was buffered ahead of time. Some people add sodium bicarbonate to buffer at home.

However! There are sellers of already buffered NAD+. Look for them and don't waste your time playing chemist.
Click to expand...
I thought it was. The GBs I've seen for NAD recommended bicarb solution to recon to raise the pH to about 6
 
TessaM said:
Multiple users now are reporting that it has a super low pH -- around 2.5, which would be like injecting vinegar. One person could barely weight-bear on their leg for a week after injecting it.

This is not how it should normally be, peptides should be buffered during manufacture. If you inject this shit it will cause intense pain and radiating tissue damage, and that will last weeks+. The only study I could find that tested the injection of super low pH solutions into volunteers stopped at pH 3.0 for ethical reasons. Volunteers rated the pain as "excruciating."

Get litmus strips to test it. If it's acidic, throw it out.

QSC is so far ignoring the problem.
Click to expand...
Where did you order the nad from
 
CallieKat said:
I tried it. Yeah. It sucks. Bad injection site reaction. Swelled up really good. SQ super bad. IM better but it still sucks. It’s true. Don’t buy it. I hope they fix it. I’m planning to get a vial from peptide sciences to see what it’s supposed to be like…
Click to expand...
Absolutely do not inject an acidic solution into a muscle. It can cause muscle tissue necrosis (death) in addition to severe pain.
 
adria37 said:
Absolutely do not inject an acidic solution into a muscle. It can cause muscle tissue necrosis (death) in addition to severe pain.
Click to expand...
This happened so long ago. As far as I know QSC has addressed this. Not sure why this has been resurrected but again it was a long time ago.

I don’t do anything in the muscle anymore. Not even B12. Not worth worrying about if I’m in the right place.
 
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