What dose is most effective for you?

Chubsbegone98

Chubsbegone98

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Curious as to what dose everyone found best results with? I've noticed it effects everyone super differently in my circle, none of us are on the same doses as eachother despite having similar builds and body weights.

I'm currently down to 175lbs from 197 ~ Diet + intense cardio was added, but i just finally titrated up from 1mg to 1.5mg as i was still fairly happy with the effects.
I haven't noticed side effects, but its probably because I've stayed at a relatively low dose.
I've seen some absolutely insane weekly doses, how many of you guys are taking over 4mg?
 
Chubsbegone98 said:
Curious as to what dose everyone found best results with? I've noticed it effects everyone super differently in my circle, none of us are on the same doses as eachother despite having similar builds and body weights.

I'm currently down to 175lbs from 197 ~ Diet + intense cardio was added, but i just finally titrated up from 1mg to 1.5mg as i was still fairly happy with the effects.
I haven't noticed side effects, but its probably because I've stayed at a relatively low dose.
I've seen some absolutely insane weekly doses, how many of you guys are taking over 4mg?
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Which one are you on?
 
Chubsbegone98 said:
My apologizies i didnt state it in the post above, Just Reta 1.5mg, waiting on my GHK To come in the mail and ill start that soon.
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What's your goal, male or female? That asked, 2mg/4weeks and 4mg/4weeks averaged 2.5lbs/week. Just took my second 6mg pin last Friday and the scale stayed the same. It happens sometimes. We'll see what happens and I'll go from there.
 
I am up to 4mg of reta now once a week. Wednesday will be my 3rd week at that dose. I started at 0.5mg on 1/5 and I have been losing 1-2lbs a week. I still have a lot of exhaustion and my appetite hasn't been that bad, so I plan on staying at 4mg for a while.
 
I just finished my first vial and started at 2mg. Today I started 4mg. Not noticing anything yet but we will see. I didn’t have any terrible side effects with 2mg and it was my first time on a GLP
 
i lost about 60lb last year on 2.5mg of tirz. never needed to go up in dose. stopped for a while before i found this gray market world and recently started back on 1.25mg evry7-8 days.
unlike some i use the peps as an tool. i like to stretch it out a little to feel my hunger come back so i can use that marker to help determine if i am truly hungry the few days after my dose or i am just bored or stuck in my routine. i dont see hunger as the end all be all enemy, or a complete failure of the medication. and at this low dose i am mainly using it to help control my insulin more than anything. i went on a cut and dropped 25lbs at the start of the year without them, then went into a maintaining phase to give myself a break from the cut but with the introduction of the 1.25 i have accidently lost another 5ish pounds just from the assistance to the blood sugar.
 
I think it mainly depends on how overweight you are, if you are trying to lose more than 10 or 15% of your body weight then you will most likely need higher doses eventually. Answering properly I would need to know age , height and what your goal is at least. Start weight was 197 current 175, so you are currently 11% down.
Reta is interesting in that it showed about 9% weight loss over a year at a dose of 1mg per week, but individual responses for weight loss and side effects vary a lot. It sounds like 1mg got you to a bit over that 9%, and I am guessing it took less than a year, so you are probably fairly sensitive to it, and you may not need much higher doses, but it depends on if you are trying to get to 160 or 125 lbs. It also depends a lot on how hungry you were trying to stick to your diet, if it was really hard work then higher doses make more sense.
 
BNLFL said:
What's your goal, male or female? That asked, 2mg/4weeks and 4mg/4weeks averaged 2.5lbs/week. Just took my second 6mg pin last Friday and the scale stayed the same. It happens sometimes. We'll see what happens and I'll go from there.
Click to expand...
Did the scale thing again this morning, down 2.5lbs and .5% BF since Friday. Pretty sure it was water weight doing Liquid IVs (500mg sodium) to get my sodium up. Shit took my BP up as well. wizzed my brains out yesterday evening and up 5 times to go last night. Back normal this morning.
 
Before knowing this site and adding homework, my friend is on Triz and lost a lot of weight over a year. The cost, circa £350, for a month, let me to talk to a friend at the gym who introduced me to Reta. It was sold in a pen with instructions of 2.5mg a week. This was my starting dose with further advice to increase to 4mg after 5 weeks which I did. This did arrive with some horrible sides, lots of air both parts. On part with a strong metallic flavour and the other being multiple trips to the toilet.

Took my food noise away and have lost around 20 pounds in 8 weeks. If I had researched rather than taking the instructions, I would have started at 0.5/1mg a week and adjusted accordingly but now here and will stay at 4mg as it is working and losing about 2 pounds a week. Once at goal loss ( a further 12 pounds) I will experiment with what dose will work for maintenance. I suppose my point is, start low, find a weekly loss that meets your goal and take it from there. As always, there will be some ups and downs with some stalls but this peptide for me isn't just losing weight. It gives me focus, an improved mood and better sleep. I am not able to say anything bad about it 🙂
 
12 weeks in, running at 2mg for the last 4, weight has stalled bouncing up and down the last few weeks. diet and gym have been consistent.

What I would like to understand from the group; why should I bump up? I'm already struggling to eat enough, but I still want to drop at least another 20-30lbs, and targeting fat loss specifically - not just a number....

For the record - 240->218 in 12 weeks (very happy with that), BF from 31% -> 23.5% trendline (not deja), I know things are moving but the last 3-4 weeks have been a bit of a challenge mentally with the scale. and I don't want to titrate up just for the sake of bumping it up...
 
WYSiWYG said:
12 weeks in, running at 2mg for the last 4, weight has stalled bouncing up and down the last few weeks. diet and gym have been consistent.

What I would like to understand from the group; why should I bump up? I'm already struggling to eat enough, but I still want to drop at least another 20-30lbs, and targeting fat loss specifically - not just a number....

For the record - 240->218 in 12 weeks (very happy with that), BF from 31% -> 23.5% trendline (not deja), I know things are moving but the last 3-4 weeks have been a bit of a challenge mentally with the scale. and I don't want to titrate up just for the sake of bumping it up...
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Given the timing - 12 weeks, it is very likely to be fluid balance changes not that weight loss has ceased, assuming the number of calories going in has not changed, and you say you are struggling to eat. The 5 - 15 lbs of fluid lost in the first few weeks does eventually sort itself out to some extent and most likely that is what is happening.
There is no need to increase doses if calorie intake is not an issue and is low enough to support weight loss, and you are not hungry. You may have to increase doses a bit eventually, but 1mg of reta caused 9% weight loss in a year in the studies, and presumably 2mg is a bit better, but there is so much individual variation it is hard to say how well that applies to any one person. You are trying to lose more like 20-25%, so will probably need more than 2mg.
I think higher doses or max doses are a good idea in the context of severe obesity , metabolic syndrome and high cardiovascular risk, but assuming that does not apply reta at lowish doses may be uniquely effective for less severe obesity.
 
I've been taking it for 10 weeks now and I'm doing well with 2 mg; my body fat percentage is still decreasing. I'll increase to 2.5 mg in a week or two. However, my sleep deteriorates every time I increase the dose, and I wake up at 4 or 5 am. Does this happen to anyone else?
 
Omxxl said:
I've been taking it for 10 weeks now and I'm doing well with 2 mg; my body fat percentage is still decreasing. I'll increase to 2.5 mg in a week or two. However, my sleep deteriorates every time I increase the dose, and I wake up at 4 or 5 am. Does this happen to anyone else?
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Oh yes, ye ole forced dawn patrol. How are you waking up? For me, I will jolt awake, there was no gradual opening my eyes and groggily waking up. I was simply awake around 3:30am most mornings. I started having a yogurt cup before bed and that fixed me right up. Sleep straight through the night now.
 
Pinngo said:
Oh yes, ye ole forced dawn patrol. How are you waking up? For me, I will jolt awake, there was no gradual opening my eyes and groggily waking up. I was simply awake around 3:30am most mornings. I started having a yogurt cup before bed and that fixed me right up. Sleep straight through the night now.
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I wake up like this, suddenly and quite energetic. Throughout the day, I feel the effects of only sleeping 5-6 hours.
 
lessthanhalf said:
Given the timing - 12 weeks, it is very likely to be fluid balance changes not that weight loss has ceased, assuming the number of calories going in has not changed, and you say you are struggling to eat. The 5 - 15 lbs of fluid lost in the first few weeks does eventually sort itself out to some extent and most likely that is what is happening.
There is no need to increase doses if calorie intake is not an issue and is low enough to support weight loss, and you are not hungry. You may have to increase doses a bit eventually, but 1mg of reta caused 9% weight loss in a year in the studies, and presumably 2mg is a bit better, but there is so much individual variation it is hard to say how well that applies to any one person. You are trying to lose more like 20-25%, so will probably need more than 2mg.
I think higher doses or max doses are a good idea in the context of severe obesity , metabolic syndrome and high cardiovascular risk, but assuming that does not apply reta at lowish doses may be uniquely effective for less severe obesity.
Click to expand...
Thanks, good view point. Through another thread and research, it became a bit more clear that I most likely need to bump the dose a little, as other signs point to adaptation having occurred. Primarily that my RHR has settled, meaning I'm not taking full advantage of the retatrutide (because there is no such thing as "retatrutide (because there is no such thing as "GLP-3")").

When I say I struggle to eat, I mean that I have to be purposeful about eating - else I look up an it's time for bed and haven't had but maybe 1Kcal's on the day. When I noticed this , I made it intentional to hit a certain mark everyday - and while somedays that feels like a second (a maybe third) job - it has helped my energy overall. I saw a small drop at that point but continue to hover in this 3-4 lb range, up and down week to week.

I have no intent of seeking max dose, what I do want to find is the max effective dose for ME. Reta has been an absolute game changer and I want to maximize that without excess.
 
Omxxl said:
I wake up like this, suddenly and quite energetic. Throughout the day, I feel the effects of only sleeping 5-6 hours.
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Interesting, I'm on the opposite side of this - takes me forever to get to sleep. And then I have no interest in getting up!! I have always been the early riser in my house - not these days
 
Omxxl said:
I've been taking it for 10 weeks now and I'm doing well with 2 mg; my body fat percentage is still decreasing. I'll increase to 2.5 mg in a week or two. However, my sleep deteriorates every time I increase the dose, and I wake up at 4 or 5 am. Does this happen to anyone else?
Click to expand...
I've been waking up at 4 the past 5 days. I'll wake up around 3:30 or so to pee and just can't go back to sleep. I just get up. Retired, so no big deal. I've had a heck of time since this last time change too. Slept good last night though and up at 5:45 which is in my normal range. 5:30-6:30. Dose change to 6mg was 2 weeks ago, but it hasn't been an issue since I started Reta.
 
BNLFL said:
I've been waking up at 4 the past 5 days. I'll wake up around 3:30 or so to pee and just can't go back to sleep. I just get up. Retired, so no big deal. I've had a heck of time since this last time change too. Slept good last night though and up at 5:45 which is in my normal range. 5:30-6:30. Dose change to 6mg was 2 weeks ago, but it hasn't been an issue since I started Reta.
Click to expand...
I woke up at like 5 am again this morning and could not go back to sleep either, didn't really think much of it until you guys commented this yesterday. Its happened a few times now for sure
 
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