What dose of reta are you at?

I know everyone is different but I read a lot of posts where people start at low doses and don't need to titrate up that high of a dose.
I'm curious as to if people go all the way up to 12mg like in the clinical trials, if if they have reaped most benefits at lower doses.

So my question is:
How long have you been taking Reta for?
Where along are you in your journey?
What is your current dosage?
Ive been taking reta for about 6 weeks, 2mg/weekly broken into two doses.
I lift 5x a week as well as 30-50 minutes cardio depending on fatigue.
I'm having great results, 5 meals a day in a caloric deficit and I'm still hungry for breakfast in the am, and have the occasional craving for a "cheat meal" here and there but I'm strict with my protocol and allow myself one cheat meal a week. And I'm doing great, losing weight at a constant, steady rate. 220lbs in the beginning down to 195. Over a 12 week period (half while using reta)
 
2mg. It works for me currently and I don’t see any need to increase as my weight loss is steady and at a good/healthy rate. I didn’t have lots to lose to begin with though.
 
I got my hands on it before I did much research and went up in dose way too quick. Started feeling appatite suppression at about 1mg a week and went up till I hit 4mg/week. I stopped there because the skin sensitivity had me ready to shave my arms and legs because the hairs felt weird on my clothes. Lost about 10lbs in a month and a half and came off. I stay at a comfortable 1mg a week now to squash food noise.
 
I was at 2.5mg for my 1st week ( I have used Reta before just took a break ). And currently at 5mg for 2-3 weeks. Down 13 kilos
 
Here's my updated path so far (6'2"; SW: 286lbs, CW: 283lbs, GW: 185lbs)
  • Week #1: 2mg
  • Week #2: 4mg
  • Week #3: 4mg
Each dose in this first month has been split doses every ~3.5 days. After starting week 1 with split doses I just found that I enjoyed multiple injection days so I kept it up for Month #1.

I've been busting my ass working out 5 days a week (Kettlebells 3x days a week+ Rowing Machine 5x days a week with weekends off), and also I hydrate quite a bit each day, typically drinking 3L per day with electrolytes. I also am eating no more than 1.4k calories each day while also making sure that I'm following my protein macro goals (~137g currently - trying to get to 160g per day).

For the first 3 weeks I didn't see much in terms of weight loss (see screenshot) but just recently saw my first big dip when weighing post-workout, so there's some encouragement. If it weren't for feeling sated after meals, I would suspect I may have a weak kit.

I think being new to the workouts (after being sedentary for years and years) coupled with electrolytes and water-weight has been obscuring my actual weight loss a bit. So I think titrating up right now would be premature. My lowest weight of 281lbs was taken post-workout, which is where I tend to see my best weigh-in numbers.

Plans For Month #2
  • I'm going to switch to shots 1x week - moving away from split dosing to see how that feels in the spirit of research.
  • It's definitely taking patience to not keep titrating up - but I'll plan to stick with 4mg per week for month 2 to give it some time.
  • I have plans to purchase from a different vendor to help rule out weak batch, since that thought has crossed my mind as well.
 

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Just getting started, but did my first dose at 0.5mg with no side effects.

I’m planning to try to maintain at a very low dose, I’ll up it to 1mg next week and reassess after 3 weeks.

I’m pretty close to my goal weight, so I want to keep my doses as low as possible. Might bump up to 2mg depending, but don’t plan on going past that.
 
I know they say start low and go slow, but I came from Tirz high dose. I titrated up over 8 weeks, then I was on 8 mg for 2 months, now down to 6 mg the last 3 weeks, because I got anhedone.
I'm very close to my goal weight, so it's slow weight loss now.

Did your anhedonia improve after going back down? I've gotten significant anhedonia from higher doses of tirz and have been titrating back down to 5 mg because I'm at goal. Anhedonia still hasn't improved
 
I'm on 2.5 mg every 7 days, and I get full very quickly. I have no trouble eating my 2,600 calories and 210 grams of protein. I'll stick with this as long as I don't feel hungry.
 
Started at 2mg a week split into 2 doses. About 6 weeks later increased to 3mg/week as food noise came back.
Now another 3 weeks on I can sense the food noise again so thinking of moving to 4mg/week.
As for weight loss, I haven't lost more than 7 pounds but I didn't have that much to lose, really now it's just belly fat mainly which is hard to lose, i'm in my 50s. I do feel like my body has recompositioned a bit though so pure weight loss doesn't tell the full story and I'm mainly doing this to get down my blood sugar which has actually worked. I already exercised daily but added a bit of extra weight training to head off muscle loss, I eat as much protein as I can.

I really liked the lack of food noise I got initially, it annoys me constantly thinking about food and when I can next eat - so if titrating up reta doesn't bring that back I might add tirz or a very small amount of cag (have never tried either).

Planning to add tesamorelin to help work on the belly fat....
 
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Did 8mg this morning.
This dose is kicking ass. It's two new vials of R50 from a vendors supplier I like, and have got itbefore. Had slowed way down on my 6mg and 7mg was useless. Down 3.2lbs, .5 BMI and .6% BF in 4 days on my Tuesday morning weigh in. I don't recall that much in a weeks yet. It's usually 1-2.5lbs/week.
 
This dose is kicking ass. It's two new vials of R50 from a vendors supplier I like, and have got itbefore. Had slowed way down on my 6mg and 7mg was useless. Down 3.2lbs, .5 BMI and .6% BF in 4 days on my Tuesday morning weigh in. I don't recall that much in a weeks yet. It's usually 1-2.5lbs/week.
Still 4 mg to go to get to the promised land of having to force feed yourself ice cream, haha.
 
I’m leveling off at 7mg/week after starting my bridge from Tirz on 1/10.

View attachment 15470
How did that transition work out for you?
I never went above 5mg of Tirz because the appetite suppression is just too extreme. Hell, I probably should have never titrated up from 2.5 to begin with...
I'm switching over to Reta in the hopes of helping me stay satiated while but allowing some of that food noise back in, as well as some of the added bennies Reta offers.
Currently on 1mg of Reta and 4mg of Tirz...will up reta by 500mcg and down the Tirz to 3 next month when I hit my goal weight
 
How did that transition work out for you?
I never went above 5mg of Tirz because the appetite suppression is just too extreme. Hell, I probably should have never titrated up from 2.5 to begin with...
I'm switching over to Reta in the hopes of helping me stay satiated while but allowing some of that food noise back in, as well as some of the added bennies Reta offers.
Currently on 1mg of Reta and 4mg of Tirz...will up reta by 500mcg and down the Tirz to 3 next month when I hit my goal weight


It’s working out fine, although I didn’t level off😂. No adverse sides.

I started creatine at the beginning of the month after my last DEXA. I’m looking forward to seeing the scale returning to showing results but hope to be rewarded for the patience on the DEXA scan in the coming weeks.
1779287670639.webp
 
Just started this monday, 1mg x 2 a week. For now.
I already feel the effect and I feel cold sometimes..
 
As an update for my higher dose. I recently switched back to doing 15mg once a week instead of 7.5mg twice a week just for convenience and have noticed 0 difference.
 
Have you noticed much of a difference between the lower dose below 4mg and the higher does where the additional glucagon burn is said to kick in ,
I switched from tirz to reta because I wanted to get the glucagon effect. My research said that the glucagon effect kicked in between 3.5-4mg based on the sigmoidal dose curve. I followed this titration approach with the goal of getting to 3.5mg as quickly as possible while still allowing adjustments if I had negative side effects.

1779345290610.webp

I had my first side effect from any GLP a week after hitting 3.5mg. I developed dysesthesia and it is finally lessening after 2 weeks. The other noticeable effect was an increased heart rate that I could feel while working at my desk. Not a negative but obviously there. The heart rate seems to be returning to normal simultaenously with the decreased skin sensation.
 
Did your anhedonia improve after going back down? I've gotten significant anhedonia from higher doses of tirz and have been titrating back down to 5 mg because I'm at goal. Anhedonia still hasn't improved
yes it got better, but over time, not instantly
 
Started a few weeks ago and just did my third pin of 1mg every 6 days, can definitely feel some hunger come back on the last day. So far it's already been working extremely well with little to no side effects. For now happy at the current dose but if it slows down I'll be going up to 2mg.

Now I'm over the initial scare of pinning myself I've got a kit of Reta on the way as well as a few other peptides to experiment with.
 
I know everyone is different but I read a lot of posts where people start at low doses and don't need to titrate up that high of a dose.
I'm curious as to if people go all the way up to 12mg like in the clinical trials, if if they have reaped most benefits at lower doses.

So my question is:
How long have you been taking Reta for?
Where along are you in your journey?
What is your current dosage?
Im currently taking Tirz, but I am putting in an order for Reat today. Plan to start at 1.5 and try to find the sweetspot for my tolerance. Seeing great results from Tirz though.
 
This dose is kicking ass. It's two new vials of R50 from a vendors supplier I like, and have got itbefore. Had slowed way down on my 6mg and 7mg was useless. Down 3.2lbs, .5 BMI and .6% BF in 4 days on my Tuesday morning weigh in. I don't recall that much in a weeks yet. It's usually 1-2.5lbs/week.
There was a green top R50.a couple months ago with 20% overfill. Maybe that's your 'problem'.
 
I started low at 2 mg for the first month then bumped up to 4mg but I’m still Sat king with Tirz as well so I don’t get any food noise. I’ll eventually stop the Tirz if I stall and bump up the Reta
How does the mix of the peptides affect you? Do you fell any side effects?
 
I did 4 months on Tirz going up to 5mg, switched to 2mg of Reta titrating up to 4mg over 4.5 months and I am now experimenting with maintenance dose of 3mg. Total lost 45 lbs. 1x week dose.
Update: now on a 2mg maintenance dose 1x week, keeping steady around 135lbs, happily back to weight lifting to get some of my muscle back.
 

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