What happens when you come off of Tessamorelin?

dorythedoggy

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I was reading that most, if not all, people in the studies who took Tess when cycled off eventually gained back all the visceral fat loss.

However, most people on these forums, I imagine, are on another peptide for weight control; Retratirude/GLP1/Traz/etc.

I was curious if anyone here has any history of take a cycle of Tes with another agonist, and what was their experience after cycling off of it.
 
The studies were done on HIV patients with lipodystrophy due to the medications used to treat it. So it would make sense that they would gain it right back since they were continuing the medication which caused it. I think with changes to ones lifestyle and diet, the fat should stay off. But just like any other weight loss, if no healthy changes are made, then the fat will return.
 
I lose a bunch of water weight when I cycle off. Sometimes I think that the tesa pumps my muscles up with water and makes my scale read lower fat percent…cause it goes up pretty quickly when I cycle off…

Who knows. Either way my body fat percent is great but I wonder if it just plays with the numbers.
 
I lose a bunch of water weight when I cycle off. Sometimes I think that the tesa pumps my muscles up with water and makes my scale read lower fat percent…cause it goes up pretty quickly when I cycle off…

Who knows. Either way my body fat percent is great but I wonder if it just plays with the numbers.
It makes sense because tesa can cause water retention, so when you stop taking it the water weight will come off, and you will be losing pounds without losing fat, so fat will make up a higher percentage of the pounds that remain.
 
Is visceral fat always above muscle?
Good question,I looked this up.
No, visceral fat is not always above muscle—in fact, it's the opposite in the abdominal area.Visceral fat (also called intra-abdominal or organ fat) is located deep inside the abdominal cavity, surrounding internal organs like the liver, intestines, stomach, and kidneys. It sits beneath (deep to) the abdominal muscles and the abdominal wall.
  • Subcutaneous fat is the layer just under the skin (the "pinchable" kind you can grab on your belly, arms, or thighs). This is above (superficial to) the muscles.
  • Visceral fat is deeper, hidden behind/under the firm abdominal muscles and not visible or pinchable from the outside.
This positioning is why visceral fat is harder to "spot-reduce" with exercises like crunches (which mainly target muscle tightening above it) and why it's more linked to health risks like insulin resistance, heart disease, and metabolic issues—its proximity to organs allows it to release fatty acids and inflammatory substances directly into the portal vein to the liver.
 

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Thank you! since being on GLPs, I ran out of pinchable fat in my stomach (used to pin there but it became troublesome) but it still sticks out a bit. I am hoping tesa does the trick.
 

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