What peptides will you never try?

[Chawolf]

I’ve spent a lot of time researching what peptides to try lately and more recently I’ve been looking at ones to stay away from. What peptides are an absolute no for you guys?

Hard no’s for me included the Melanotans. I’ve had melanoma before, so will never touch it.

Adipotide because I’m scared of its reputation and potential kidney damage (even though it’s supposed to reversible.)

I did glow protocol but will not use it anymore due to tb500 and tumor progression promotion. Again, just due to me and my family’s history the benefit does not outweigh the risk.

And any peptide combination that contains ghk-cu. I’ve tried glow and klow and then just copper with KPV. Even purchasing from different sources I’ve never had any positive results. Not much negative though aside from huge welts left from the copper. But it didn’t do anything to improve my skin, so it’s not worth a huge painful welts and bruises it left.

What about you guys, any peptides or regimens that are hard no’s for you?

 

[sheilarae74]

I don't see myself needing anything that isn't fat loss or body recomp related. I do want to try GHK-cu.

 

[Flexon]

I will say almost all of them, but will probably use whatever has any chance of success if I found myself in situation to be desperate.

 

[Grogu]

I purchased some Cargilintide and probably won’t use it. The pH issue and fibrils has me spooked. But I spook quite easily, so it’s about me and not the Cargi 😂

 

[reyqaz]

For me it would be the peptide that's increases hunger, such as Ghrelin. I don't think I'd be needing that ever!

 

[professorpeppy]

I purchased some Cargilintide and probably won’t use it. The pH issue and fibrils has me spooked. But I spook quite easily, so it’s about me and not the Cargi 😂

I am here as well. i have done two doses 0.25mg and 0.5mg the past 2 weeks for the first time ( has been sat in the freezer for months ) and every time i pin im like oh no fibrils infecting my precious brain..

still pinning it though aha maybe its taking over my faculties

 

[Grogu]

I am here as well. i have done two doses 0.25mg and 0.5mg the past 2 weeks for the first time ( has been sat in the freezer for months ) and every time i pin im like oh no fibrils infecting my precious brain..

still pinning it though aha maybe its taking over my faculties

My kit has been in the freezer for months too! Out of sight, out of mind, literally 🤣😂🤣.

I think that the risk is probably very low as I don't think fibrils will travel from the injection site to the brain and that the molecules are probably too large to pass the blood-brain barrier.

Did you do anything about the pH issue?

 

[chewonmysac]

PT-141. Bought it. Will not use. Turns out, when you lose 90lbs, I have to remove the "Closed for the Season" sign from my Penis. Works like I am 20 yrs old again.

 

[randompersonrandom]

I've tried tirz, reta, survo, KLOW, Epitalon, NAD+ (never again), SS-31, and MOTS-C (never again).

I will keep using some glp1 or other for forever, and intend to keep running the KLOW and Epitalon periodically, and am open to SS-31 occasionally.

Everything else, I believe is either unnecessary, likely snake oil, or dangerous. I've reached the end of my own personal "inject all the things and see what happens" journey.

 

[BNLFL]

No desire besides what I'm on now, Reta.

 

[ambot88]

I've tried tirz, reta, survo, KLOW, Epitalon, NAD+ (never again), SS-31, and MOTS-C (never again).

I will keep using some glp1 or other for forever, and intend to keep running the KLOW and Epitalon periodically, and am open to SS-31 occasionally.

Everything else, I believe is either unnecessary, likely snake oil, or dangerous. I've reached the end of my own personal "inject all the things and see what happens" journey.

I literally just ordered MOT-C and NAD+ why do we hate them?

 

[GrandmaJ]

Anything with the potential for tumor growth. It just seems like the risk/reward is not worth it.

 

[Minkster]

I’ve spent a lot of time researching what peptides to try lately and more recently I’ve been looking at ones to stay away from. What peptides are an absolute no for you guys?

Hard no’s for me included the Melanotans. I’ve had melanoma before, so will never touch it.

Adipotide because I’m scared of its reputation and potential kidney damage (even though it’s supposed to reversible.)

I did glow protocol but will not use it anymore due to tb500 and tumor progression promotion. Again, just due to me and my family’s history the benefit does not outweigh the risk.

And any peptide combination that contains ghk-cu. I’ve tried glow and klow and then just copper with KPV. Even purchasing from different sources I’ve never had any positive results. Not much negative though aside from huge welts left from the copper. But it didn’t do anything to improve my skin, so it’s not worth a huge painful welts and bruises it left.

What about you guys, any peptides or regimens that are hard no’s for you?

Pretty much same list and same reasons. But I do want some topical ghkcu. Currently just taking Reta.

 

[SeaGypsy]

Currently running Tirz, HGH, Ss-31, Nad+, MT2. Will start MOTS after the SS. Just completed a KLOW protocol. I will soon start GHK-CU and I am considering a Reta switch but not just yet. I don't have any that I am dead set against. If I'm interested in something I will research it and make the determination if I really feel it would be worth it for me.
I am on the other side with the GHK-CU. I absolutely noticed changes in my skin after the KLOW run, my turkey neck lessened considerably. My skin and hair were in such bad shape tho, still a ways to go but I could see the progress.

 

[SeaGypsy]

I've tried tirz, reta, survo, KLOW, Epitalon, NAD+ (never again), SS-31, and MOTS-C (never again)

Did you have bad reactions to the NAD and Mots? Or did it just do nothing for you?
I'm just curious....

 

[foffspam111]

I like to stay open to any tool that will assist my body on my wellness journey. With that said there is one peptide that I have run across that won’t be on my research list anytime soon if ever.
Dermorphin Peptide

The peptide is a natural opioid that binds as an agonist with high potency and selectivity to mu opioid receptors. Dermorphin is about 30–40 times more potent than morphine.

Something of this nature doesn’t fit with my goals and journey. There might be some that actually need this peptide and it may have a benefit for some. But it is a dangerous road to go down for most.

My recommendation to anyone starting on this path is:
Get your bloodwork done
Have a goal based around your bloodwork and over all health
Research what tools can assist you to get to that goal. (Sleep, diet, exercise, Supplements, peptides, etc.
Then execute the plan and journal your results as you go.

 

[Chili777]

I think those that are angiogenic can stay on the shelf. The rest of the bunch are just ones that I haven't gotten to yet, or don't match my goals.

 

[tubby]

For some reason the title of this post reminded me of the old (circa 2010) chemistry blog "Things I won't work with," which was always amazing to read. I have a chemistry background, but even without that, it was a trip!

 

[sfkid]

Currently running Tirz, HGH, Ss-31, Nad+, MT2. Will start MOTS after the SS. Just completed a KLOW protocol. I will soon start GHK-CU and I am considering a Reta switch but not just yet. I don't have any that I am dead set against. If I'm interested in something I will research it and make the determination if I really feel it would be worth it for me.
I am on the other side with the GHK-CU. I absolutely noticed changes in my skin after the KLOW run, my turkey neck lessened considerably. My skin and hair were in such bad shape tho, still a ways to go but I could see the progress.

My man... you are a petrie dish 💪

 

[vewdew34]

For me one that I will never try again is DSIP, never worked for me.

 

[Coulter1966]

Nothing IM. I am just not ready for that and probably will never be.

 

[FNG33]

I might have missed a couple. Need to check the spreadsheet. 🤔

 

[randompersonrandom]

Did you have bad reactions to the NAD and Mots? Or did it just do nothing for you?
I'm just curious....

I literally just ordered MOT-C and NAD+ why do we hate them?

If you don't mind me asking, what did you hate about nad+ and mots-c? I've been looking at these for a minute.

NAD+ did nothing positive that I could perceive, and it hurt and was a lot of volume, which grosses me out. MOTS-C hurt, MAY have granted some energy, but hurt and left lumps that remained for months (one of which is still there.)

I'll tolerate some hurt because I really do believe KLOW is doing SOMETHING. But if it hurts and doesn't seem to do anything for me, no thanks. And the MOTS-C leaving those for-way-too-long lumps was what made "and there's some risk to this" real for me.

 

[janedoe]

At this point, though I really want to try it..LL37. The Alzheimer’s potential is far greater than my risk tolerance.

 

[AlexSilver]

At this point, though I really want to try it..LL37. The Alzheimer’s potential is far greater than my risk tolerance.

From my notes:
LL37 - Never use - works as described but also causes massive inflammation on several levels, definitely causes and/or accelerates tumor growth, promotes histamine release, and exacerbates arthritis and skin conditions like psoriasis and eczema.

 

[Dos-Dox]

Adipotide, Semaglutide, Orexin A/B because there’s no need to try them.

Too late to say never try on MOTS-c or PT-141, but I wouldn’t plan to run either of them again.

Jury is still out on a lot of the others, but I’m open to most if they fit my needs and risk tolerance.

 

[oldrunnerguy]

I do not intend to try anything except Reta, Tirz, BPC-157, Mots-C, and Epithalon.

 

[Enyola]

When I came here, I promised myself I wouldn’t go beyond GLP-1 agonists. I’m well aware that I can get swept up in the general mood. But I’ve decided to stick to my limit. It would feel wrong to take risks when there isn’t a really strong reason to do so.
So "all except" is my answer.

 

[Calm Logic]

I've tried tirz, reta, survo, KLOW, Epitalon, NAD+ (never again), SS-31, and MOTS-C (never again).

I will keep using some glp1 or other for forever, and intend to keep running the KLOW and Epitalon periodically, and am open to SS-31 occasionally.

Everything else, I believe is either unnecessary, likely snake oil, or dangerous. I've reached the end of my own personal "inject all the things and see what happens" journey.

For the people I know, KPV is their favorite in KLOW. It's at least more feelz for them (in helping their pain), compared to BPC and the rest in KLOW.

 

[AlexSilver]

For the people I know, KPV is their favorite in KLOW. It's at least more feelz for them (in helping their pain), compared to BPC and the rest in KLOW.

Heck, I love KPV all by itself. It's awesome!