What Percentage of Body Weight Have You Lost?

[m100568]

I was looking at the mouse study on Retatrutide and cancer. https://www.nature.com/articles/s44324-025-00054-5 The cancer implications are very interesting on its own, but that is not the purpose of this post. The other thing that caught my eye in the study is that the mice lost 40% to 41% of body weight and stabilized there. We have the Phase II data of 24.2%, but people were still losing weight after 48 weeks. There is no published data on when it plateaus. EL has extended the studies, so it looks like they are trying to find that out.

I have been stacking Tirz and Reta for 8 1/2 months. I have lost 35% of my body weight and I am still losing. I would like to get down to 40% to reach my ideal weight. My question is for people on maintenance or close to maintenance; what percentage of your body weight have you lost? Has anyone hit 40%, or more?

 

[dogmom]

I calculated about 35% from when I started GLPs. From my highest though which was years before I started GLPs, I weigh less than half of what I used to. I don't know the exact percentage.

 

[chmuse]

Down 18% so far. Sema since October, average 1.7lb per week even including stalls.

 

[bbrewer]

27% in 9 months, down to 33 to 23 BMI. Entering maintenance mode now, but still not eating desert. The other crash test dummy in the research facility lost 32%

 

[hexagonal]

about 28% since october

Tirz until Dec, Reta since then. Started on TRT in October as well. Ipa/Tesa for a bit over two months, two month break, 4IU of HGH now.

5 days of fairly serious lifting very consistently every week, very inconsistent cardio.

 

[Galora]

 

[Goreandglitter]

I’m at 41% 15 months on tirz still losing.

 

[spookymarshmallow]

48%! 240 -> 125 on Tirz over about 18 months. I’m pretty happy with where I am currently, and have been trying out maintenance for the last month. But I’d be lying if I said it wasn’t tempting to try to lose 5 more so I could say 50%.

 

[AndyPanda]

48%! 240 -> 125 on Tirz over about 18 months. I’m pretty happy with where I am currently, and have been trying out maintenance for the last month. But I’d be lying if I said it wasn’t tempting to try to lose 5 more so I could say 50%.

That is crazy. Seeing all of the people who are at 40+% makes me ask the question… was that your goal, or did you move the goal posts once you started losing?

 

[Skidude]

226 to 164 since September. Most per week was first 5 weeks now average is diluted.
about 27% but purposely slowed down at 25. have no idea if it helped but the lb per week concerned me at that BMI level.

A very satisfied customer though.

 

[nonyabizznez]

226>152 33% 5'9 male. Moved the goal post for maintenance cush.

 

[DwightTheDelight]

My question is for people on maintenance or close to maintenance; what percentage of your body weight have you lost? Has anyone hit 40%, or more?

Down 45% in 15 months.

That is crazy. Seeing all of the people who are at 40+% makes me ask the question… was that your goal, or did you move the goal posts once you started losing?

Before I began losing weight, there were several arbitrary scale numbers I thought would make me happy, but every time I reach that number, I'm still not happy. I'm hoping to be done soon, but keep saying, "1 more month." I have so much loose skin, you could jump out of a plane with me on your back and safely land a few minutes later.

 

[DwightTheDelight]

about 28% since october

Tirz until Dec, Reta since then. Started on TRT in October as well. Ipa/Tesa for a bit over two months, two month break, 4IU of HGH now.

5 days of fairly serious lifting very consistently every week, very inconsistent cardio.

Has your weight been increasing since starting hgh and trt or have you been able to continue losing?

 

[Int96]

31% in 8 months with a stack of Reta and Sema. Down from 260 to 181 currently.

 

[britt1263]

I’m at 41% 15 months on tirz still losing.

What was your starting weight

 

[tyrus-pgh]

252 > 160: 36% I started tirz on 3/26/2024. Pinning 5.0mg weekly now

 

[Healthmaster]

265-217 so 18%. Couldn’t be happier, just have no idea where to go from here. Never thought I’d be under 230 in my life lol

 

[ruisenor]

243-169 (30%) since September on Reta. I am now at my stretch goal weight and really just focused on getting to an optimal body fat percentage, which may mean another 5-6 lbs to go. Max dose I have taken is 10mg.

 

[hotdog!]

I've lost 24% of my body weight, but I started at 254 so had a lot to lose (80+ lbs). A BMI chart would make me lose 100+ lbs to be a "normal" weight but I could never realistically fit the "normal" BMI labels without looking gaunt and sick.
Mostly lost my weight on Tirz (I'm up to 10mg). But I did try stacking Reta for ~3 months before the side effects made me give up. If I remember I got up to 4mg.

 

[normal]

119lbs / 47% in 10 months.

I'm actually up a few pounds in muscle over the last few weeks. Loving life. Tirz is some amazing stuff